• Istituto di Biologia e Patologia Molecolari

Colotti, Gianni; Fiorillo, Annarita; Ilari, Andrea.  
Metal- and metalloid-containing drugs for the treatment of trypanosomatid diseases. 
Frontiers in bioscience (Online): 954-966
 
De Cola A.; Franceschini M.; Di Matteo A.; Colotti G.; Celani R.; Clemente E.; Ippoliti R.; Cimini A.M.; Dhez A.C.; Vallee B.; Raineri F.; Cascone I.; Destouches D.; De Laurenzi V.; Courty J.; Federici L. 
N6L pseudopeptide interferes with nucleophosmin protein-protein interactions and sensitizes leukemic cells to chemotherapy. 
Cancer letters (Print): 272-282
 
Righi G.; Pelagalli R.; Isoni V.; Tirotta I.; Marini M.; Palagri M.; Dallocchio R.; Dessì A.; Macchi B.; Frezza C.; Forte G.; Dalla Cort A.; Portalone G.; Bovicelli P. 
Synthesis of potential HIV integrase inhibitors inspired by natural polyphenol structures. 
Natural product research (Print): 1893-1901
 
Ardini M.; Howes B.D.; Fiorillo A.; Falvo E.; Sottini S.; Rovai D.; Lantieri M.; Ilari A.; Gatteschi D.; Spina G.; Chiancone E.; Stefanini S.; Fittipaldi M. 
Study of manganese binding to the ferroxidase centre of human H-type ferritin. 
Journal of inorganic biochemistry: 103-112
 
Milano, Teresa; Angelaccio, Sebastiana; Tramonti, Angela; di Salvo, Martino Luigi; Nogues, Isabel; Contestabile, Roberto; Pascarella, Stefano.  
A Comprehensive Computational Analysis of Mycobacterium Genomes Pinpoints the Genes Co-occurring with YczE, a Membrane Protein Coding Gene Under the Putative Control of a MocR, and Predicts its Function. 
Interdisciplinary Sciences: Computational Life Sciences
 
Roberta Ghelli, Patrizia Brunetti, Nadia Napoli, Angelo De Paolis, Valentina Cecchetti, Tomohiko Tsuge, Giovanna Serino, Minami Matsui, Gianmarco Rinaldi, Gianna Aurora Palumbo, Fabrizio Barozzi, Paolo Costantino and Maura Cardarelli.  
A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis. 
The Plant cell (Online): 620-637
 
Capauto, Davide; Colantoni, Alessio; Lu, Lei; Santini, Tiziana; Peruzzi, Giovanna; Biscarini, Silvia; Morlando, Mariangela; Shneider, Neil A; Caffarelli, Elisa; Laneve, Pietro; Bozzoni, Irene.  
A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons. 
Molecular neurobiology
 
Cristofaro I.; Spinello Z.; Matera C.; Fiore M.; Conti L.; De Amici M.; Dallanoce C.; Tata A.M. 
Activation of M2 muscarinic acetylcholine receptors by a hybrid agonist enhances cytotoxic effects in GB7 glioblastoma cancer stem cells. 
Neurochemistry international: 52-60
 
Gulía C, Baldassarra S, Zangari A, Briganti V, Gigli S, Gaffi M, Signore F, Vallone C, Nucciotti R, Costantini FM, Pizzuti A, Bernardo S, Porrello A, Piergentili R. 
Androgen insensitivity syndrome. 
European review for medical and pharmacological sciences: 3873-3887
 
Biscarini S.; Capauto D.; Peruzzi G.; Lu L.; Colantoni A.; Santini T.; Shneider N.A.; Caffarelli E.; Laneve P.; Bozzoni I. 
Characterization of the lncRNA transcriptome in mESC-derived motor neurons: Implications for FUS-ALS. 
Stem cell research (Amsterdam. Print)
 
Folgiero V, Sorino C, Pallocca M, De Nicola F, Goeman F, Bertaina V, Strocchio L, Romania P, Pitisci A, Iezzi S, Catena V, Bruno T, Strimpakos G, Passananti C, Mattei E, Blandino G, Locatelli F, Fanciulli M. 
Che-1 is targeted by c-Myc to sustain proliferation in pre-B-cell acute lymphoblastic leukemia. 
EMBO reports (Print)
 
Porcu C.; Antonucci L.; Barbaro B.; Illi B.; Nasi S.; Martini M.; Licata A.; Miele L.; Grieco A.; Balsano C. 
Copper/MYC/CTR1 interplay: A dangerous relationship in hepatocellular carcinoma. 
Oncotarget: 9325-9343
 
di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo.  
Corrigendum to "Pyridoxine-5?-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g > A (P.·Arg116gln) mutation" [Mol. Genet. Metab. 122/1-2 (2017) 135-142]. 
Molecular genetics and metabolism (Print)
 
Tramonti, Angela; Tramonti, Angela; Paiardini, Alessandro; Paone, Alessio; Bouzidi, Amani; Giardina, Giorgio; Guiducci, Giulia; Magnifico, Maria Chiara; Rinaldo, Serena; McDermott, Lee; Menendez, Javier A.; Menendez, Javier A.; Contestabile, Roberto; Cutruzzolà, Francesca.  
Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes. 
Archives of biochemistry and biophysics (Print): 71-79
 
Scaglione, Antonella; Monteonofrio, Laura; Parisi, Giacomo; Cecchetti, Cristina; Siepi, Francesca; Rinaldo, Cinzia; Giorgi, Alessandra; Verzili, Daniela; Zamparelli, Carlotta; Savino, Carmelinda; Soddu, Silvia; Vallone, Beatrice; Montemiglio, Linda Celeste.  
Effects of Y361-auto-phosphorylation on structural plasticity of the HIPK2 kinase domain. 
Protein science (Print): 725-737
 
A. Stoppacciaro, S. Di Vito and P. Filetici.  
Epigenetic factors and mitochondrial biology in yeast: a new paradigm for the study of cancer metabolism?. 
Frontiers in Pharmacology
 
Bidollari E.; Rotundo G.; Ferrari D.; Candido O.; Bernardini L.; Consoli F.; De Luca A.; Santimone I.; Lamorte G.; Ilari A.; Squitieri F.; Vescovi A.L.; Rosati J. 
Generation of induced pluripotent stem cell line, CSSi004-A (2962), from a patient diagnosed with Huntington's disease at the presymptomatic stage. 
Stem cell research (Amsterdam. Print): 145-148
 
Di Martile, Marta; Desideri, Marianna; Tupone, Maria Grazia; Buglioni, Simonetta; Antoniani, Barbara; Mastroiorio, Carlotta; Falcioni, Rita; Ferraresi, Virginia; Baldini, Nicola; Biagini, Roberto; Milella, Michele; Trisciuoglio, Daniela; Del Bufalo, Donatella.  
Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma. 
Oncogenesis20
 
Loria R.; Laquintana V.; Bon G.; Trisciuoglio D.; Frapolli R.; Covello R.; Amoreo C.A.; Ferraresi V.; Zoccali C.; Novello M.; Del Bufalo D.; Milella M.; Biagini R.; D'Incalci M.; Falcioni R. 
HMGA1/E2F1 axis and NFkB pathways regulate LPS progression and trabectedin resistance. 
Oncogene (Basingstoke): 1-13
 
1 Marco Iuliano, 1 Giorgio Mangino, 2 Maria Vincenza Chiantore, 1 Maria Simona Zangrillo, 3 Rosita Accardi, 3 Massimo Tommasino, 2,4 Gianna Fiorucci, 1 Giovanna Romeo.  
Human Papillomavirus E6 and E7 oncoproteins affect the cell microenvironment by classical secretion and extracellular vesicles delivery of inflammatory mediators. 
Cytokine (Phila. Pa., Print)
 
Giuffre, Alessandro; Vicente, Joao B. 
Hydrogen Sulfide Biochemistry and Interplay with Other Gaseous Mediators in Mammalian Physiology. 
Oxidative medicine and cellular longevity (Online)2018:6290931
 
Cocco, Elisa; Leo, Manuela; Canzonetta, Claudia; Di Vito, Serena; Mai, Antonello; Rotili, Dante; Di Napoli, Arianna; Vecchione, Andrea; De Nunzio, Cosimo; Filetici, Patrizia; Stoppacciaro, Antonella.  
KAT3B-p300 and H3AcK18/H3AcK14 levels are prognostic markers for kidney ccRCC tumor aggressiveness and target of KAT inhibitor CPTH2. 
Clinical epigenetics (Print)
 
Piovesana R.; Melfi S.; Fiore M.; Magnaghi V.; Tata A.M. 
M2 muscarinic receptor activation inhibits cell proliferation and migration of rat adipose-mesenchymal stem cells. 
Journal of cellular physiology (Print): 5348-5360
 
Carla Sappino a, Alessandra Mari a, Agnese Mantineo a, Mauro Moliterno a, Matteo Palagri a, Chiara Tatangelo a, Lorenza Suber b, Paolo Bovicelli c, Alessandra Ricelli c, and Giuliana Righi *c.  
New chiral amino alcohol ligands for catalytic enantioselective addition of diethylzincs to aldehydes. 
Organic & biomolecular chemistry: 1860-1870
 
Vallone C, Rigon G, Gulia C, Baffa A, Votino R, Morosetti G, Zaami S, Briganti V, Catania F, Gaffi M, Nucciotti R, Costantini FM, Piergentili R, Putignani L, Signore F.  
Non-Coding RNAs and Endometrial Cancer. 
Genes (Basel)
 
Iachettini S.; Trisciuoglio D.; Rotili D.; Lucidi A.; Salvati E.; Zizza P.; Di Leo L.; Del Bufalo D.; Ciriolo M.R.; Leonetti C.; Steegborn C.; Mai A.; Rizzo A.; Biroccio A. 
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells. 
Cell death and disease
 
Ardini M.; Howes B.D.; Fiorillo A.; Falvo E.; Sottini S.; Rovai D.; Lantieri M.; Ilari A.; Gatteschi D.; Spina G.; Chiancone E.; Stefanini S.; Fittipaldi M. 
Study of manganese binding to the ferroxidase centre of human H-type ferritin. 
Journal of inorganic biochemistry: 103-112
 
Giardina, Giorgio; Paone, Alessio; Tramonti, Angela; Lucchi, Roberta; Marani, Marina; Magnifico, Maria Chiara; Bouzidi, Amani; Pontecorvi, Valentino; Guiducci, Giulia; Zamparelli, Carlotta; Rinaldo, Serena; Paiardini, Alessandro; Contestabile, Roberto; Cutruzzola, Francesca.  
The catalytic activity of serine hydroxymethyltransferase is essential for denovo nuclear dTMP synthesis in lung cancer cells. 
The FEBS journal (Print): 3238-3253
 
Tramonti, Angela; Tramonti, Angela; Nardella, Caterina; di Salvo, Martino L.; Pascarella, Stefano; Contestabile, Roberto.  
The MocR-like transcription factors: Pyridoxal 5'-phosphate-dependent regulators of bacterial metabolism. 
The FEBS journal (Print)
 
Fiorillo A.; Petrosino M.; Ilari A.; Pasquo A.; Cipollone A.; Maggi M.; Chiaraluce R.; Consalvi V. 
The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme. 
PloS one
 
Capobianco G.; Brunetti P.; Bonifazi G.; Costantino P.; Cardarelli M.; Serranti S. 
The use of micro-energy dispersive X-ray fluorescence spectrometry (µ-XRF) combined with a multivariate approach to determine element variation and distribution in tobacco seedlings exposed to arsenate. 
Spectrochimica acta. Part B, Atomic spectroscopy: 132-140
 
Ilari A.; Genovese I.; Fiorillo F.; Battista T.; De Ionna I.; Fiorillo A.; Colotti G. 
Toward a Drug Against All Kinetoplastids: From LeishBox to Specific and Potent Trypanothione Reductase Inhibitors. 
Molecular pharmaceutics (Print): 3069-3078
 
Leo M.; Fanelli G.; Di Vito S.; Traversetti B.; La Greca M.; Palladino R.A.; Montanari A.; Francisci S.; Filetici P. 
Ubiquitin protease Ubp8 is necessary for S. cerevisiae respiration. 
Biochimica et biophysica acta. Molecular cell research: 1491-1500
 
Di Francesco, Laura; Verrico, Annalisa; Asteriti, Italia Anna; Rovella, Paola; Cirigliano, Pietro; Guarguaglini, Giulia; Schinina, Maria Eugenia; Lavia, Patrizia.  
Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays. 
Scientific reports (Nature Publishing Group)