Veronica Morea, Allegra Via, Teresa Colombo, Mario Incarnato
Computational tools are developed and applied to study biological macromolecules and systems, with the following aims:
FACE2FACE
a web-based service to analyse interfaces between biological macromolecules
Computational tools are developed and applied to study biological macromolecules and systems, with the following aims:
- elucidate the fundamental principles underlying macromolecule structure, function, folding and evolution, and the mutual relationships among these features;
- build macromolecular models at atomic level;
- predict protein function;
- design proteins variants or short peptides endowed with desired properties;
Genomic, transcriptomic, proteomic and other large scale data (”big data”) are analysed using computational and statistical methods.
In particular, we develop tools in the following areas: