
Veronica Morea, Allegra Via, Teresa Colombo, Mario Incarnato

Fast, Comprehensive, and User Customizable Macromolecule Interface Analysis with FACE2FACE.
Di Micco P, Incarnato M, Pascarella G, Via A, Morea V. J Chem Inf Model. 2025. doi: 10.1021/acs.jcim.5c00771
Computational tools are developed and applied to study biological macromolecules and systems, with the following aims:
FACE2FACE
a web-based service to analyse interfaces between biological macromolecules

Fast, Comprehensive, and User Customizable Macromolecule Interface Analysis with FACE2FACE.
Di Micco P, Incarnato M, Pascarella G, Via A, Morea V. J Chem Inf Model. 2025. doi: 10.1021/acs.jcim.5c00771
Computational tools are developed and applied to study biological macromolecules and systems, with the following aims:
- elucidate the fundamental principles underlying macromolecule structure, function, folding and evolution, and the mutual relationships among these features;
- build macromolecular models at atomic level;
- predict protein function;
- design proteins variants or short peptides endowed with desired properties;
Genomic, transcriptomic, proteomic and other large scale data (”big data”) are analysed using computational and statistical methods.
In particular, we develop tools in the following areas: