• Istituto di Biologia e Patologia Molecolari

Publications 2010

Sultana, R (Sultana, Rukhsana); Perluigi, M (Perluigi, Marzia)2; Newman, SF (Newman, Shelley F.); Pierce, WM (Pierce, William M.)3,4; Cini, C (Cini, Chiara)2; Coccia, R (Coccia, Raffaella)2; Butterfield, DA (Butterfield, D. Allan)1.  
Redox Proteomic Analysis of Carbonylated Brain Proteins in Mild Cognitive Impairment and Early Alzheimer's Disease.
Antioxidants & redox signalling ;12(3): 327-36

Bellapadrona G, Ardini M, Ceci P, Stefanini S, Chiancone E.
Dps proteins prevent Fenton mediated oxidative damage by trapping hydroxyl radicals within the protein shell.
Free radical biology & medicine;48(2): 292-7

Ceci P, Chiancone E, Kasyutich O, Bellapadrona G, Castelli L, Fittipaldi M, Gatteschi D, Innocenti C, Sangregorio C.
Synthesis of Iron Oxide Nanoparticles in Listeria innocua Dps (DNA-Binding Protein from Starved Cells): A Study with the Wild-Type Protein and a Catalytic Centre Mutant.
Chemistry (Weinh., Print);16(2):709-17.

Mastronicola D; Testa F; Forte E; Bordi E; Pucillo LP; Sarti P; Giuffrè A.
Flavohemoglobin and nitric oxide detoxification in the human protozoan parasite Giardia intestinalis.
Biochemical and biophysical research communications (Print);399(4): 654-8

Montemiglio LC; Gianni S; Vallone B; Savino C.
Azole drugs trap cytochrome P450 EryK in alternative conformational states.
Biochemistry (Easton);49(43): 9199-206

Di Matteo A; Calosci N; Gianni S; Jemth P; Brunori M; Travaglini-Allocatelli C.
Structural and functional characterization of CcmG from Pseudomonas aeruginosa, a key component of the bacterial cytochrome c maturation apparatus.
Proteins (Print) ;78(10): 2213-21

Haq SR, Jürgens MC, Chi CN, Koh CS, Elfström L, Selmer M, Gianni S, Jemth P.
The plastic energy landscape of protein folding: a triangular folding mechanism with an equilibrium intermediate for a small protein domain.
The Journal of biological chemistry (Print) ;285(23): 18051-9

Scaloni F, Federici L, Brunori M, Gianni S.
Deciphering the folding transition state structure and denatured state properties of nucleophosmin C-terminal domain.
Proceedings of the National Academy of Sciences of the United States of America ;107(12): 5447-52

Zamparelli C, Macquaide N, Colotti G, Verzili D, Seidler T, Smith GL, Chiancone E.
Activation of the cardiac Na(+)-Ca(2+) exchanger by sorcin via the interaction of the respective Ca(2+)-binding domains.
Journal of Molecular and Cellular Cardiologyl;49(1): 132-41

Alaleona F, Franceschini S, Ceci P, Ilari A, Chiancone E.
Thermosynechococcus elongatus DpsA binds Zn(II) at a unique three histidine-containing ferroxidase center and utilizes O2 as iron oxidant with very high efficiency, unlike the typical Dps proteins.
The FEBS journal (Print);277(4): 903-17

Chiancone E, Ceci P.
The multifaceted capacity of Dps proteins to combat bacterial stress conditions: Detoxification of iron and hydrogen peroxide and DNA binding.
Biochimica et biophysica acta. G,  General subjects (Print);1800(8): 798-805

Chiancone E, Ceci P.
Role of Dps (DNA-binding proteins from starved cells) aggregation on DNA.
Frontiers in bioscience (Print);15: 122-131

Kasyutich O, Ilari A, Fiorillo A, Tatchev D, Hoell A, Ceci P.
Silver ion incorporation and nanoparticle formation inside the cavity of Pyrococcus furiosus ferritin: structural and size-distribution analyses.
Journal of the American Chemical Society (Print);132(10): 3621-7

Ceci P, Chiancone E, Kasyutich O, Bellapadrona G, Castelli L, Fittipaldi M, Gatteschi D, Innocenti C, Sangregorio C.
Synthesis of iron oxide nanoparticles in Listeria innocua Dps (DNA-binding protein from starved cells): a study with the wild-type protein and a catalytic centre mutant.
Chemistry.;16(2): 709-17

Prastaro A, Ceci P, Chiancone E, Boffi A, Fabrizi G, Cacchi S.
Homocoupling of arylboronic acids and potassium aryltrifluoroborates catalyzed by protein-stabilized palladium nanoparticles under air in water.
Tetrahedron letters;51: 2550-2552

Federici L; Arcovito A; Scaglione GL; Scaloni F; Lo Sterzo C; Di Matteo A; Falini B; Giardina B; Brunori M.
Nucleophosmin C-terminal leukaemia-associated domain interacts with G-rich quadruplex forming DNA.
The Journal of biological chemistry (Print;285(48): 37138-49

Miele R, Lattanzi R, Bonaccorsi di Patti MC, Paiardini A, Negri L, Barra D.
Expression of Bv8 in Pichia pastoris to identify structural features for receptor binding.
Protein expression and purification (Print) ;73(1): 10-4.

Barks, H.(a)  , R. Buckley(a), G A. Grieves(a), E. Di Mauro (b) , N.Hud (a)  and   T. Orlando  (a).  
Guanine, Adenine, and Hypoxanthine Production in UV-Irradiated Formamide Solutions: Relaxation of the Requirements for Prebiotic Purine Nucleobase Formation.
ChemBioChem (Print);11(9): 1240-3

Cossetti C. (1), Crestini C.(2) , Saladino R.(3) , Di Mauro E.(1).  
Borate Minerals and RNA Stability.
Biopolymers (Print) Orig Life Evol Biosph. 2011 Aug;41(4):307-16  

Cesarini E, Mariotti FR, Cioci F, Camilloni G.
RNA polymerase I transcription silences noncoding RNAs at the ribosomal DNA locus in Saccharomyces cerevisiae.
Eukaryot Cell. ;9(2): 325-35.

Gaetano C, Capogrossi M, Fanciulli M, Filetici P, Piaggio G.
Epigenetics in rome: Breaking news from the chromatin remodeling and human disease workshop.
Epigenetics;5(3): 249-25
Laneve P, Gioia U, Andriotto A, Moretti F, Bozzoni I, Caffarelli E.  
A minicircuitry involving REST and CREB controls miR-9-2 expression during human neuronal differentiation.
Nucleic acids research;38(20): 6895-905

Giani Prosseda; Alessia Mazzola; Maria Letizia Di Martino; Denis Tielker; Gioacchino Micheli; Bianca Colonna.  
A temperature-induced narrow DNA curvature range sustains the maximum activity of a bacterial promoter in vitro.
Biochemistry (Easton);49(13): 2778-85

Ruotolo R, Tosi F, Vernarecci S, Ballario P, Mai A, Filetici P, Ottonello S.
Chemogenomic profiling of the cellular effects associated with histone H3 acetylation impairment by a quinoline-derived compound.
Genomics (S. Diego Calif.);96(5): 272-80

Saladino R., Neri V., Crestini C., Costanzo, G., Graciotti, M., And  Di Mauro E.
The role of the Formamide/Zirconia system in the synthesis of nucleobases and biogenic carboxylic acid derivatives.
Journal of molecular evolution;71(2): 100-10

Travers A, Hiriart E, Churcher M, Caserta M, Di Mauro E.
The DNA sequence-dependence of nucleosome positioning in vivo and in vitro.
Journal of biomolecular structure & dynamics ;27(6): 713-24

Vernarecci S; Tosi F; Filetici P.  
Tuning acetylated chromatin with HAT inhibitors: a novel tool for therapy.
Epigenetics;5(2): 105-11

Asteriti IA, Rensen WM, Lindon C, Lavia P and Guarguaglini G.  
The Aurora-A/TPX2 complex: A novel oncogenic holoenzyme?.
Biochimica et biophysica acta, CR. Reviews on cancer;1806(2):2 30-9

Ciciarello M, Roscioli E, Di Fiore B, Di Francesco L, Sobrero F, Bernard D, Mangiacasale R, Harel A, Schininà ME, Lavia P.
Nuclear reformation after mitosis requires downregulation of the Ran GTPase effector RanBP1 in mammalian cells.
Chromosoma (Berl., Print);119(6): 651-68

Palermo V, Cundari E, Mangiapelo E, Falcone C, Mazzoni C.  
Yeast lsm pro-apoptotic mutants show defects in S-phase entry and progression.
Cell cycle (Georget. Tex.);9(19): 3991-6

Meschini R, Berni A, Marotta E, Filippi S, Fiore M, Mancinelli P, Natarajan AT, Palitti F.
DNA repair mechanisms involved in the removal of DBPDE-induced lesions leading to chromosomal alterations in CHO cells.
Cytogenetic and genome research (Print. ed.);128(1-3): 124-30

Filippi S, Palitti F, Martínez-López W, Fiore M, Natarajan A.
Relationship between DNA repair and formation of sister chromatid exchanges and chromatid aberrations under the influence of poly(ADP-ribose) polymerase inhibition by 3-aminobenzamide.
Cytogenetic and genome research (Print. ed.) ;128(1-3): 118-23

Ferretti C;Totta P; Fiore M; Mattiuzzo M; Schillaci T; Ricordy R; Di Leonardo A; Degrassi F;.  
Expression of the kinetochore protein Hec1 during the cell cycle in normal and cancer cells and its regulation by the pRb pathway.
Cell cycle (Georget. Tex.);9(20): 4174-82

Raffa GD, Raimondo D, Sorino C, Cugusi S, Cenci G, Cacchione S, Gatti M, Ciapponi L.
Verrocchio, a Drosophila OB fold-containing protein, is a component of the terminin telomere-capping complex.
Genes & development ;24(15): 1596-601.

Ferretti R, Palumbo V, Di Savino A, Velasco S, Sbroggiò M, Sportoletti P, Micale L, Turco E, Silengo L, Palumbo G, Hirsch E, Teruya-Feldstein J, Bonaccorsi S, Pandolfi PP, Gatti M, Tarone G, Brancaccio M.
Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis.
Developmental cell ;18(3): 486-95

Benna C, Bonaccorsi S, Wülbeck C, Helfrich-Förster C, Gatti M, Kyriacou CP, Costa R, Sandrelli F.
Drosophila timeless2 is required for chromosome stability and circadian photoreception.
Current biology;20(4): 346-52

Piersanti S, Remoli C, Saggio I, Funari A, Michienzi S, Sacchetti B, Gehron Robey P, Riminucci M Bianco P.
Transfer, analysis and reversion of the fibrous dysplasia cellular phenotype in human skeletal progenitors.
Journal of bone and mineral research;25(5): 1103-16

Bianco P, Robey PG, Saggio I, Riminucci M.
Mesenchymal stem cells in human bone marrow (skeletal stem cells) - a critical discussion of their nature, identity, and significance in incurable skeletal disease.
Human gene therapy ;21(9): 1057-66

Bruno T; Desantis A; Bossi G; Di Agostino S; Sorino C; De Nicola F; Iezzi S; Franchitto A; Benassi B; Galanti S; La Rosa F; Floridi A; Bellacosa A; Passananti C; Blandino G; Fanciulli M.
Che-1 promotes tumor cell survival by sustaining mutant p53 transcription and inhibiting DNA damage response activation.
Cancer cell (Print);18(2): 122-34

Anastasi E, Granato T, Marchei GG, Viggiani V, Colaprisca B, Comploj S, Reale MG, Frati L, Midulla C.
Ovarian tumor marker HE4 is differently expressed during the phases of the menstrual cycle in healthy young women.
Tumor biology;31(5): 411-5

Giubettini M, Asteriti IA, Scrofani J, De Luca M, Lindon C, Lavia P, Guarguaglini G.
Control of Aurora-A stability via its interaction with TPX2.
Journal of cell science (Online);124(1): 113-22.

Riminucci M, Gehron Robey P, Saggio I, Bianco P.
Skeletal progenitors and the GNAS gene: fibrous dysplasia of bone read through stem cells.
Journal of molecular endocrinology;45(6): 355-64.

Corbo RM, Ulizzi L, Piombo L, Scacchi R.
Association of ACE I/D polymorphism and recurrent miscarriages in an Italian population with a pre-modern reproductive pattern.
Annals of human biology ;38(1): 102-5

Incitti T., De Angelis F.G., Cazzella V., Sthandier O., Pinnarò C.,  Legnini I., Bozzoni I.
Exon skipping and Duchenne Muscular Dystrophy therapy: selection of the most active U1 snRNA-antisense able to induce dystrophin exon.
Molecular therapy (Print);18(9): 1675-82

Corbo RM, Ulizzi L, Positano L, Scacchi R.
Association of CYP19 and ESR1 Pleiotropic Genes With Human Longevity.
J Gerontol A Biol Sci Med Sci.;66(1): 51-5

Cacchiarelli D.,  Martone J., Girardi E., Cesana M., Incitti T.,  Nicoletti C., Santini T., Sthandier O., Auricchio A., Musarò A., Bozzoni I.
microRNAs Involved in Molecular Circuitries Relevant for the Duchenne Muscular Dystrophy Pathogenesis Are Controlled by the Dystrophin/nNOS Pathway.
Cell metabolism;12(4): 341-51

Perluigi M; Di Domenico F; Blarzino C; Foppoli C; Cini C; Giorgi A; Grillo C; De Marco F; Butterfield DA; Schininà ME; Coccia R.  
Effects of UVB-induced oxidative stress on protein expression and specific protein oxidation in normal human epithelial keratinocytes: a proteomic approach.
Proteome science;8: 13

Gianni, S., Ivarsson, Y., De Simone, A., Travaglini-Allocatelli, C., Brunori, M., Vendruscolo M.
Characterization of the Structure of a Misfolded Intermediate Populated during the Folding Process of a PDZ domain.
Nature structural & molecular biology (Online);17(12): 1431-7

Di Mauro  E.
On the emergence of pre-genetic information.

Rensen WM, Lavia P.  
RAN, member of the RAS oncogene family.

Passananti C; Corbi N; Onori A; Di Certo MG; Mattei E.
Transgenic mice expressing an artificial zinc finger regulator targeting an endogenous gene.
Methods in molecular biology (Clifton N.J.);649: 183-206

Nasi Sergio.  

Nasi Sergio.  
Oncogeni e oncosoppressori.

Cundari E., Soddu S., Chessa L., Prodosmo A.
Metodo per la identificazione in vitro di portatori sani di atassia telangiectasia e relativo  kit.

Silvestri R., La Regina G., Hamel E., Brancale A., Lavia P., Novellino E.
Derivati indolici e loro uso in campo medico.

Di Certo MG1; Corbi N2; Strimpakos G1,7; Onori A2; Luvisetto S3; Severini C1; Guglielmotti A4; Batassa EM2; Pisani C2,7; Floridi A7; Benassi B5,8; Fanciulli M5,8; Magrelli A6; Mattei E1,8; Passananti C2,8.  
The artificial gene Jazz, a transcriptional regulator of utrophin, corrects the dystrophic pathology in mdx mice.
Human molecular genetics (Print);19(5): 752-60.

Francis M.,A. Kohler,C. Murat, R Balestrini, PM. Coutinho, O. Jaillon, B. Montanini, E. Morin,  Noel, R. Percudani, B. Porcel, A. Rubini, A. Amicucci, J. Amselem, V. Anthouard, S. Arcioni, F. Artiguenave, JM. Aury, P. Ballario, A Bolchi, et al.
Périgord black truffle genome uncovers evolutionary origins and mechanisms of symbiosis.
Nature (Lond.);19(5): 752-60

I Ruberti; G Sessa; A Ciolfi;.  
Molecular mechanisms of plant adaptation to canopy shade.
Journal of biotechnology;30(5): 1047-58  supplemento: S112-S113

Isabella Ascone;Carmelinda Savino;Richard Kahn;Roger Fourme.  
Flexibility of the Cu,Zn superoxide dismutase structure investigated at 0.57GPa.
Acta crystallographica. Section D, Biological crystallography.;66(6): 654-63

AM De Leonardis 1; F D'Orso 2; G Morelli 2;     I Ruberti  3; L Cattivelli 1; AM Mastrangelo 1.  
A conserved group of CCCH zinc finger proteins is involved in response to abiotic stresses in durum wheat and Arabidopsis.
Journal of biotechnology;S150: S491-S491

AM De Leonardis*; F D'orso**; G Morelli**; I Ruberti***; L Cattivelli*; R Papa*; AM Mastrangelo*.  
A conserved group of CCCH zinc finger proteins is involved in response to abiotic stresses in durum wheat and Arabidopsis.

Valentina    Forte 1;    Simona    Baima 1;    Marco Felici 1,2; Ida Ruberti 3, Giorgio Morelli 1.  
Identification of a Regulatory Loop Controlling Xylem Production.
Journal of biotechnology;150S: 5493-5493

S.    Salvucci 1;     L.    Farina 2 ;    G.    Morelli 3 ;    I.    Ruberti 1.  
Behavioral dynamic modelling of fast responses: the Escherichia coli SOS system as a case study.
Journal of biotechnology;150S: S524-S524

G Sessa (1); A Ciolfi (1); M Possenti (2); S Salvucci (1); M Carabelli (1); G Morelli (2); I Ruberti (1).  
Regulatory networks in shade avoidance response.

Sultana, R (Sultana, Rukhsana)1,2,3; Di Domenico, F (Di Domenico, Fabio)4; Tseng, M (Tseng, Michael)5; Cai, JA (Cai, Jian)6; Noel, T (Noel, Teresa)7; Chelvarajan, RL (Chelvarajan, R. Lakshman); Pierce, WD (Pierce, William D.)6; Cini, C (Cini, Ciara)4; Bondada, S (Bondada, Subbarao)8; St Clair, DK (St Clair, Daret K.)7; Butterfield, DA (Butterfield, D. Allan)1,2,3.  
Doxorubicin-induced thymus senescence.
Journal of proteome research (Print);9(12): 6232-41

Di Domenico F; Owen JB; Sultana R; Sowell RA ; Perluigi M; Cini C; Cai JA; Pierce WD; Butterfield DA.  
The Wheat Germ Agglutinin-Fractionated Proteome of Subjects With Alzheimer's Disease and Mild Cognitive Impairment Hippocampus and Inferior Parietal Lobule: Implications for Disease Pathogenesis and Progression.
Journal of neuroscience research;88(16): 3566-77

Di Domenico F ; Sultana R; Tiu GF; Scheff NN; Perluigi M; Cini C; Butterfield DA.  
Protein levels of heat shock proteins 27, 32, 60, 70, 90 and thioredoxin-1 in amnestic mild cognitive impairment: An investigation on the role of cellular stress response in the progression of Alzheimer disease.
Brain research;1333: 72-81

Di Domenico, F (Di Domenico, Fabio)1,2,3; Casalena, G (Casalena, Gabriella)1,2,4; Sultana, R (Sultana, Rukhsana)1,2; Cai, JA (Cai, Jian)5; Pierce, WM (Pierce, William M.)5; Perluigi, M (Perluigi, Marzia)3; Cini, C (Cini, Chiara)3; Baracca, A (Baracca, Alessandra)4; Solaini, G (Solaini, Giancarlo)4; Lenaz, G (Lenaz, Giorgio)4; Jia, J (Jia, Jia)6; Dziennis, S (Dziennis, Suzan)6; Murphy, SJ (Murphy, Stephanie J.)6; Alkayed, NJ (Alkayed, Nabil J.)6; Butterfield, DA (Butterfield, D. Allan)1,2.  
Involvement of stat3 in mouse brain development and sexual dimorphism: A proteomics approach.
Brain research;1362: 1-12

Perluigi, M (Perluigi, M.)1; Di Domenico, F (Di Domenico, F.)1; Giorgi, A (Giorgi, A.)1; Schinina, ME (Schinina, M. E.)1; Coccia, R (Coccia, R.)1; Cini, C (Cini, C.)1; Bellia, F (Bellia, F.)2; Cambria, MT (Cambria, M. T.)2; Cornelius, C (Cornelius, C.)2; Butterfield, DA (Butterfield, D. A.)3,4; Calabrese, V (Calabrese, V.)2,5.  
Redox Proteomics in Aging Rat Brain: Involvement of Mitochondrial Reduced Glutathione Status and Mitochondrial Protein Oxidation in the Aging Process.
Journal of neuroscience research;88(16): 3498-507

S Baima*; F Fantasia*; V Forte*;  I Ruberti**; G Morelli*.  
Investigating the role of two small uORFs in the translational control of ATHB8 in Arabidopsis.

AM De Leonardis*; F D'Orso**; G Morelli**;  I Ruberti***;  L Cattivelli*; R Papa*;  AM Mastrangelo*.  
A conserved group of  CCCH zinc finger proteins is involved in response to abiotic stresses  in durum wheat and Arabidopsis.

Gabriele, S.; Rizza, A.; Martone, J.; Circelli, P.; Costantino, P.; Vittorioso, P.
The Dof protein DAG1 mediates PIL5 activity on seed germination by negatively regulating the GA biosynthetic gene AtGA3ox1.
Plant journal (Print);61(2): 312-23

M. Somma, F. Renda, V. Naim, E. Bucciarelli, C. Pellacani, A. Palena, M. Gatti.  
Int6, a New Regulator of Metaphase-Anaphase Transition in Drosophila S2 Cells.
Molecular biology of the cell (Online);21

Mattei E.1, Di Certo MG.1, Corbi N.2, Strimpakos G.1, Luvisetto S.1, Severini C.3, Onori A.2, Pisani C.2, Passananti C.2.  
The artificial gene Jazz, a transcriptional regulator of utrophin, corrects the dystrophic pathology in mdx mice.
Transgenic research;19(5):752-60

Gaetano C, Capogrossi M, Fanciulli M, Filetici P, Piaggio G.  
Epigenetics in rome: Breaking news from the chromatin remodeling and human disease workshop.
Epigenetics;5(3): 249-251