• Istituto di Biologia e Patologia Molecolari

Publications 2011

Colotti G; Ilari A. 
Polyamine metabolism in Leishmania: from arginine to trypanothione. 
Amino acids (Wien, Print);40: 269-285
Zampieri M, Guastafierro T, Calabrese R, Ciccarone F, Bacalini MG, Reale A, Perilli M, Passananti C, Caiafa P. 
ADP-ribose polymers localized on Ctcf-Parp1-Dnmt1 complex prevent methylation of Ctcf target sites. 
Biochemical journal (Lond., 1984)
Salvatori L, Ravenna L, Caporuscio F, Principessa L, Coroniti G, Frati L, Russo MA, Petrangeli E. 
Action of retinoic acid receptor on EGFR gene transactivation and breast cancer cell proliferation: Interplay with the estrogen receptor. 
Biomedicine & pharmacotherapy
Stoppoloni D, Salvatori L, Biroccio A, D'Angelo C, Muti P, Verdina A, Sacchi A, Vincenzi B, Baldi A, Galati R. 
Aromatase inhibitor exemestane has antiproliferative effects on human mesothelioma cells. 
Journal of thoracic oncology
Mangino G, Percario ZA, Fiorucci G, Vaccari G, Acconcia F, Chiarabelli C, Leone S, Noto A, Horenkamp FA, Manrique S, Romeo G, Polticelli F, Geyer M, Affabris E. 
HIV-1 Nef induces proinflammatory state in macrophages through its acidic cluster domain: involvement of TNF alpha receptor associated factor 2. 
PloS one
Anastasi E, Granato T, Coppa A, Manganaro L, Giannini G, Comploj S, Frati L, Midulla C. 
HE4 in the Differential Diagnosis of a Pelvic Mass: A Case Report. 
International journal of molecular sciences (Online);18: 627-632
Lo Monaco E, Tremante E, Cerboni C, Melucci E, Sibilio L, Zingoni A, Nicotra MR, Natali PG, Giacomini P. 
Human leukocyte antigen E contributes to protect tumor cells from lysis by natural killer cells. 
Neoplasia (N.Y.N.Y.)
Rosanò L, Cianfrocca R, Spinella F, Di Castro V, Nicotra MR, Lucidi A, Ferrandina G, Natali PG, Bagnato A. 
Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells. 
Clinical cancer research (Print)
Savino M, Annibali D, Carucci N, Favuzzi E, Cole MD, Evan GI, Soucek L, Nasi S. 
The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy. 
PloS one
Bacalini MG, Di Lonardo D, Catizone A, Ciccarone F, Bruno T, Zampieri M, Guastafierro T, Calabrese R, Fanciulli M, Passananti C, Caiafa P, Reale A. 
Poly(ADP-ribosyl)ation affects stabilization of Che-1 protein in response to DNA damage. 
DNA repair (Print)
Ruberti I; Sessa G; Ciolfi A; Possenti M; Carabelli M; Morelli G.  
Plant adaptation to dynamically changing environment: The shade avoidance response. 
Biotechnology advances
Mottier-Pavie V., Cenci G., Vernì F., Gatti M. and Bonaccorsi S. 
Phenotypic analysis of misato function reveals roles of noncentrosomal microtubules inDrosophila spindle formation. 
Journal of cell science
Damasco C.; Lembo A.; Somma MP.; Gatti M.; Di Cunto F.; and Provero P. 
A signature inferred from Drosophila mitotic genes predicts survival of breast cancer patients. 
PloS one
Raffa GD., Capponi L., Cenci G. and Gatti M. 
Terminin: a protein complex that mediates epigenetic maintenance of Drosophila telomeres. 
Szafer-Glusman E, Fuller MT, Giansanti MG. 
Role of survivin in cytokinesis revealed by a separation-of-function allele. 
Molecular biology of the cell
Mattiuzzo M1; G. Vargiu P1; Totta, M. Fiore1, C. Ciferri, A. Musacchio and F. Degrassi.  
Abnormal Kinetochore-Generated Pulling Forces from Expressing a N-Terminally Modified Hec1. 
PloS one
Romagnoli G, Cundari E, Negri R, Crescenzi M, Farina L, Giuliani A, Bianchi MM. 
Synchronous protein cycling in batch cultures of the yeast Saccharomyces cerevisiae at log growth phase. 
Experimental cell research
Cherubini G, Naim V, Caruso P, Burla R, Bogliolo M, Cundari E, Benihoud K, Saggio I, Rosselli F. 
The FANC pathway is activated by adenovirus infection and promotes viral replication-dependent recombination. 
Nucleic acids research
Silvestri R, La Regina G, Bai R, Rensen W, Coluccia A, Piscitelli F, Gatti V, Bolognesi A, Lavecchia A, Granata I, Porta A, Maresca B, Soriani A, Iannitto ML, Mariani M, Santoni A, Brancale A, Ferlini C, Dondio MG, Varasi M, Mercurio C, Hamel E, Lavia P a.  
Design and Synthesis of 2-Heterocyclyl-3-arylthio-1H-indoles as Potent Tubulin Polymerization and Cell Growth Inhibitors with Improved Metabolic Stability. 
Journal of medicinal chemistry
Asteriti IA, Giubettini M, Lavia P and Guarguaglini G. 
Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces. 
Molecular cancer
Giubettini M, Asteriti IA, Scrofani J, De Luca M, Lindon C, Lavia P and  Guarguaglini G. 
Control of Aurora-A stability through interaction with TPX2. J Cell Sci. 124:113-22. 
Journal of cell science
Trombetta B, Cruciani F, Sellitto D, Scozzari R.  
A new topology of the human Y chromosome haplogroup E1b1 (E-P2) revealed through the use of newly characterized binary polymorphisms. 
PloS one
Cruciani F, Trombetta B, Massaia A, Destro-Bisol G, Sellitto D, Scozzari R.  
A revised root for the human Y chromosomal phylogenetic tree: The origin of patrilineal diversity in Africa. 
American journal of human genetics
Corbo RM, Gambina G, Broggio E, Scacchi R. 
Influence of variation in the follicle-stimulating hormone receptor gene (FSHR) and age at menopause on the development of Alzheimer's disease in women. 
Dementia and geriatric cognitive disorders
Scacchi R, Ruggeri M, Corbo RM. 
Variation of the butyrylcholinesterase (BChE)  and acetylcholinesterase (AChE) genes in coronary artery disease. 
Clinica chimica acta (Print)
Corbo RM, Ulizzi L, Piombo L, Scacchi R. 
Association of ACE I/D polymorphism and recurrent miscarriages in an Italian population with a pre-modern reproductive pattern. 
Annals of human biology
Costanzo G, Pino S, Botta G, Saladino R, Di Mauro E.  
May cyclic nucleotides be a source for abiotic RNA synthesis?. 
Origins of life and evolution of the biosphere
Saladino R, Crestini C, Cossetti C, Di Mauro E, Deamer D.  
Catalytic effects of Murchison material: Prebiotic synthesis and degradation of RNA precursors. 
Origins of life and evolution of the biosphere
Saladino R, Barontini M, Cossetti C, Di Mauro E, Crestini C. 
The effects of borate minerals on the synthesis of nucleic acid bases, amino acids and biogenic carboxylic acids from formamide. 
Origins of life and evolution of the biosphere
Pino S, Costanzo G, Giorgi A, Di Mauro E.  
Sequence Complementarity-Driven Nonenzymatic Ligation  of RNA. 
Biochemistry (Easton)
Caffarelli E, Filetici P.  
Epigenetic regulation in cancer development. 
Frontiers in bioscience (Print)
Orecchia A, Scarponi C, Di Felice F, Cesarini E, Avitabile S, Mai A, Mauro ML, Sirri V, Zambruno G, Albanesi C, Camilloni G, Failla CM.  
Sirtinol treatment reduces inflammation in human dermal microvascular endothelial cells. 
PloS one
Celona B, Weiner A, Di Felice F, Mancuso FM, Cesarini E, Rossi RL, Gregory L, Baban D, Rossetti G, Grianti P, Pagani M, Bonaldi T, Ragoussis J, Friedman N, Camilloni G, Bianchi ME, Agresti  A.  
Substantial Histone Reduction Modulates Genomewide Nucleosomal Occupancy and Global Transcriptional Output. 
PLoS biology
Bastonini E, Verdone L, Morrone S, Santoni A, Settimo G, Marsili G, La Fortezza M, Di Mauro E, Caserta M.  
Transcriptional modulation of a human monocytic cell line exposed to PM(10) from an urban area. 
Environmental research (N. Y. N. Y., Print)
Cacchiarelli D., Incitti T., Martone J., Cesana M., Cazzella V., Santini T., Sthandier O. and Bozzoni I. 
miR-31 modulates dystrophin expression:  novel implications in Duchenne Muscular Dystrophy therapy. 
EMBO reports (Print)
Vincenti S, Brillante N, Lanza V, Bozzoni I, Presutti C, Chiani F, Etna MP, Negri R. 
HUVEC Respond to Radiation by Inducing the Expression of Pro-angiogenic microRNAs. 
Radiation research
Cesana M., Cacchiarelli D.Legnini I., Santini T., Sthandier O., Chinappi M., Tramontano A. and Bozzoni I. 
Key ceRNA role for the long non-codingRNA linc-MD1 in the control of muscle differentiation. 
Cell (Cambridge)
Ilari A., Baiocco P, Messori L, Fiorillo A, Boffi A, Gramiccia M, Di Muccio T, Colotti G. 
A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition. 
Amino acids (Wien, Print);42: 803-811
Ilari A, Alaleona F, Petrarca P, Battistoni A, Chiancone E. 
The X-ray structure of the zinc transporter ZnuA from Salmonella enterica discloses a unique triad of zinc-coordinating histidines. 
Journal of Molecular Biology
Baiocco P; Ilari A; Ceci P; Orsini S; Gramiccia M; Di Muccio T; Colotti G. 
Inhibitory Effect of Silver Nanoparticles on Trypanothione Reductase Activity and Leishmania infantum Proliferation. 
ACS medicinal chemistry letters;2: 230-233
Fiorillo A, Federico R, Polticelli F, Boffi A, Mazzei F, Di Fusco M, Ilari A, Tavladoraki P. 
The structure of maize polyamine oxidase K300M mutant in complex with the natural substrates provides a snapshot of the catalytic mechanism of polyamine oxidation. 
The FEBS journal (Print)
Testa F; Mastronicola D, Cabelli DE, Bordi E, Pucillo P, Sarti P, Saraiva LM, Giuffrè A, Teixeira M. 
The superoxide reductase from the early diverging eukaryote Giardia intestinalis. 
Free radical biology & medicine;51: 1567-1574
Robin S; Arese M; Forte E; Sarti P; Giuffrè A; Soulimane T.  
A sulfite respiration pathway from Thermus thermophilus and the key role of a newly identified cytochrome c550. 
Journal of bacteriology (Print);193: 3988-3997
Borisov VB; Forte E; Sarti P; Giuffrè A. 
Catalytic intermediates of cytochrome bd terminal oxidase at steady-state: ferryl and oxy-ferrous species dominate. 
Biochimica et biophysica acta. Bioenergetics;1807: 503-509
Mastronicola D; Giuffrè A; Testa F; Mura A, Forte E, Bordi E, Pucillo LP, Fiori PL, Sarti P. 
Giardia intestinalis escapes oxidative stress by colonizing the small intestine: a molecular hypothesis. 
IUBMB life (Print);63: 21-25
Ceci, P., Forte, E., Di Cecca, G., Fornara, M., and Chiancone, E. 
The characterization of Thermotoga maritima ferritin reveals an unusual subunit dissociation behavior and efficient DNA protection from iron-mediated oxidative stress. 
Extremophiles (Tokyo, Print)
Ceci, P., Di Cecca, G., Falconi, M., Oteri, F., Zamparelli, C., and E. Chiancone. 
Effect of the charge distribution along the “ferritin-like” pores of Dps proteins on the iron incorporation process. 
Kostiainen, M.A., Ceci, P., Fornara, M., Hiekkataipale, P., Kasyutich, O., Nolte, R.J., Cornelissen, J.J., Desautels, R.D., van Lierop, J. 
Hierarchical self-assembly and optical disassembly for controlled switching of magnetoferritin nanoparticle magnetism. 
ACS nano
Yu Z, Bekker M, Tramonti A, Cook GM, van Ulsen P, Scheffers DJ, de Mattos JT, De Biase D, Luirink J. 
Activators of the glutamate-dependent acid resistance system alleviate deleterious effects of YidC depletion in Escherichia coli. 
Journal of bacteriology (Print)
Perluigi M; Di Domenico F; Fiorini A; Cocciolo A; Giorgi A; Foppoli C; Butterfield DA; Giorlandino M; Giorlandino C; Schininà ME; Coccia R. 
Oxidative stress occurs early in Down syndrome pregnancy: a redox proteomics analysis of amniotic fluid. 
Proteomics. Clinical applications (Print);5: 167-178
Montanari A; De Luca C; Di Micco P; Morea V; Frontali L; Francisci S. 
Structural and functional role of bases 32 and 33 in the anticodon loop of yeast mitochondrial tRNAIle. 
RNA (Camb., Print);17: 1983-1996
Grieco P, Luca V, Auriemma L, Carotenuto A, Saviello MR, Campiglia P, Barra D, Novellino E, Mangoni ML. 
Alanine scanning analysis and structure-function relationships of the frog-skin antimicrobial peptide temporin-1Ta. 
Journal of peptide science (Print)
Marsango S, Bonaccorsi di Patti MC, Barra D, Miele R. 
Evidence that prokineticin receptor 2 exists as a dimer in vivo. 
Cellular and molecular life sciences (Print. ed.)
Ragno R, Gioia U, Laneve P, Bozzoni I, Mai A, Caffarelli E. 
Identification of Small-Molecule Inhibitors of the XendoU Endoribonucleases Family. 
ChemMedChem (Print)
Cacchiarelli D., Legnini I. Martone J., D’Amico A., Bertini E. and Bozzoni I. 
miRNAs as serum biomarkers for Duchenne Muscular Dystrophy. 
EMBO molecular medicine (Print)
Lattao R., Bonaccorsi S., Guan X., Wasserman SA. and Gatti M. 
Tubby-tagged balancers for the Drosophila X and second chromosomes. 
Fly (Austin, Tex.)
Gonzalez L, Corradi S, Thomassen LC, Martens JA, Cundari E, Lison D, Kirsch-Volders M. 
Methodological approaches influencing cellular uptake and cyto-(geno) toxic effects of nanoparticles. 
Journal of biomedical nanotechnology (Print)
Cruciani F, Trombetta B, Antonelli C, Pascone R, Valesini G, Scalzi V, Vona G, Melegh B, Zagradisnik B, Assum G, Efremov GD, Sellitto D, Scozzari R.  
Strong intra- and inter-continental differentiation revealed by Y chromosome SNPs M269, U106 and U152. 
Saladino R., Crestini C., Pino S., Costanzo G., Di Mauro E. 
Formamide and the origin of life. 
Physics of life reviews (Print)
Pino S, Trifonov E, Di Mauro E.  
On the observable transition to living matter. 
Testa F; Giuffrè A; Mastronicola D; Forte E; Sarti P. 
Enzymatic detoxification of O2 and NO in the human parasite Giardia intestinalis: a minireview. 
Indian journal of biotechnology (Print);10: 404-409
Corbo RM, Ulizzi L, Positano L, Scacchi R. 
Association of CYP19 and ESR1 pleiotropic genes with human longevity. 
Pino S, Di Mauro E.  
Consciousness and the Universe. 
Passananti C, Di Certo MG, Onori A, Corbi N.  
Nucleic acid codifying for a utrophin transcription specific regulating protein, codified thereby and uses thereof. 
Silvestri R, La Regina G, Hamel E, Brancale A, Lavia P. and Novellino E. 
Indolic derivatives and use thereof in medical field. 
Fittipaldi, M., Innocenti, C., Ceci, P., Sangregorio, C., Castelli, L., Sorace, L., and Gatteschi, D.  
Looking for quantum effects in magnetic nanoparticles using the molecular nanomagnet approach. 
Sbardella G, Mai A, Bartolini S, Castellano S, Cirilli R, Rotili D, Milite C, Santoriello M, Orlando S, Sciamanna I, Serafino A, Lavia P, Spadafora C. 
Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors. 
Journal of medicinal chemistry;54: 5927-5936
Pino S, Biasiucci M, Scardamaglia M, Gigli G, Betti MG, Mariani C, Di Mauro E.  
Nonenzymatic Ligation of an RNA Oligonucleotide Analyzed by Atomic Force Microscopy.