Laing, Adam G.; Lorenc, Anna; del Molino del Barrio, Irene; Das, Abhishek; Fish, Matthew; Monin, Leticia; Muñoz-Ruiz, Miguel; McKenzie, Duncan R.; Hayday, Thomas S.; Francos-Quijorna, Isaac; Kamdar, Shraddha; Joseph, Magdalene; Davies, Daniel; Davis, Richard; Jennings, Aislinn; Zlatareva, Iva; Vantourout, Pierre; Wu, Yin; Sofra, Vasiliki; Cano, Florencia; Greco, Maria; Theodoridis, Efstathios; Freedman, Joshua; Gee, Sarah; Chan, Julie Nuo En; Ryan, Sarah; Bugallo-Blanco, Eva; Peterson, Pärt; Kisand, Kai; Haljasmägi, Liis; Chadli, Loubna; Moingeon, Philippe; Martinez, Lauren; Merrick, Blair; Bisnauthsing, Karen; Brooks, Kate; Ibrahim, Mohammad A.A.; Mason, Jeremy; Lopez Gomez, Federico; Babalola, Kola; Abdul-Jawad, Sultan; Cason, John; Mant, Christine; Seow, Jeffrey; Graham, Carl; Doores, Katie J.; Di Rosa, Francesca; Edgeworth, Jonathan; Shankar-Hari, Manu; Hayday, Adrian C.
A dynamic COVID-19 immune signature includes associations with poor prognosis.
Nature medicine (Print): 1623-1635
Mascia A; Cirafici AM; Bongiovanni A; Colotti G; Lacerra G; Di Carlo M; Digilio FA; Liguori GL; Lanati A; Kisslinger A;.
A failure mode and effect analysis (FMEA)-based approach for risk assessment of scientific processes in non-regulated research laboratories.
Accreditation and quality assurance
Stefano Sechi, Anna Frappaolo,, Angela Karimpour-Ghahnavieh, Roberta Fraschini and Maria Grazia Giansanti.
A novel coordinated function of Myosin II with GOLPH3 controls centralspindlin localization during cytokinesis in Drosophila.
Journal of cell science (Online)
Di Rienzo L.; Milanetti E.; Testi C.; Montemiglio L.C.; Baiocco P.; Boffi A.; Ruocco G.
A novel strategy for molecular interfaces optimization: The case of Ferritin-Transferrin receptor interaction.
Computational and Structural Biotechnology Journal: 2678-2686
Ahmed Abdelbaki, H. Begum Akman, Marion Poteau, Rhys Grant, Olivier Gavet, Giulia Guarguaglini, Catherine Lindon.
AURKA destruction is decoupled from its activity at mitotic exit but essential to suppress interphase activity.
Journal of cell science (Online)
Kiraga,L., Cerutti,G., Braniewska,A., Strzemecki,D., Sas,Z., Boffi,A., Savino,C., Montemiglio,L.C., Turnham,D., Seaton,G., Bonamore,A., Clarkson,R., Dabkowski,A., Paisey,S.J., Taciak,B., Kucharzewska,P., Rygiel,T.P., Król,M.
Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice.
International journal of molecular sciences (Print): 4990-5006
Parry G.; Provart N.J.; Brady S.M.; Uzilday B.; Adams K.; Araujo W.; Aubourg S.; Baginsky S.; Bakker E.; Barenfaller K.; Batley J.; Beale M.; Beilstein M.; Belkhadir Y.; Mendel G.; Berardini T.; Bergelson J.; Blanco-Herrera F.; Brady S.; Braun H.-P.; Briggs S.; Brownfield L.; Cardarelli M.; Castellanos-Uribe M.; Coruzzi G.; Dassanayake M.; De Jaeger G.; Dilkes B.; Doherty C.; Ecker J.; Edger P.; Edwards D.; El Kasmi F.; Eriksson M.; Exposito-Alonso M.; Falter-Braun P.; Fernie A.; Ferro M.; Fiehn O.; Friesner J.; Greenham K.; Guo Y.; Hamann T.; Hancock A.; Hauser M.-T.; Heazlewood J.; Ho C.-H.; Horak H.; Huala E.; Hwang I.; Iuchi S.; Jaiswal P.; Jakobson L.; Jiang Y.; Jiao Y.; Jones A.; Kadota Y.; Khurana J.; Kliebenstein D.; Knee E.; Kobayashi M.; Koch M.; Krouk G.; Larson T.; Last R.; Lepiniec L.; Li S.; Lurin C.; Lysak M.; Maere S.; Malinowski R.; Maumus F.; May S.; Mayer K.; Mendoza-Cozatl D.; Mendoza-Poudereux I.; Luis Micol J.; Millar H.; Mock H.-P.; Mukhtar K.; Mukhtar S.; Murcha M.; Nakagami H.; Nakamura Y.; Nicolov L.; Nikolau B.; Nowack M.; Nunes-Nesi A.; Palmgren M.; Parry G.; Patron N.; Peck S.; Pedmale U.; Perrot-Rechenmann C.; Pieruschka R.; Pio-Beltran J.; Pires J.C.; Provart N.; Rajjou L.; Reiser L.; Rhee S.; Rigas S.; Rolland N.; Romanowski A.; Savaldi-Goldstein S.; Schmitz R.; Schulze W.; Seki M.; Shimizu K.K.; Slotkin K.; Small I.; Somers D.; Sozzani R.; Spillane C.; Srinivasan R.; Taylor N.; Tello-Ruiz M.-K.; Thelen J.; Tohge T.; Town C.; Toyoda T.; Uzilday B.; Walley J.; Ware D.; Weckwerth W.; Whitelegge J.; Wienkoop S.; Wright C.; Wrzaczek M.; Yamazaki M.; Yanovsky M.; Zarsky V.; Zhong X.; Van De Peer Y.; Van Wijk K.; Von Gillhaussen P.
Current status of the multinational Arabidopsis community.
Plant Direct
Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio.
Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
ACS medicinal chemistry letters: 977-983
Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino.
Discovery of the First Human Arylsulfatase A Reversible Inhibitor Impairing Mouse Oocyte Fertilization.
ACS chemical biology: 1349-1357
Parisi G.; Freda I.; Exertier C.; Cecchetti C.; Gugole E.; Cerutti G.; D'auria L.; Macone A.; Vallone B.; Savino C.; Montemiglio L.C.
Dissecting the cytochrome p450 olep substrate specificity: Evidence for a preferential substrate.
Biomolecules: 1-17
Di Rosa, Francesca.
Editorial: Serafino Zappacosta and the Ceppellini School: A Pioneer Model for Nurturing Education in Immunology.
Frontiers in immunology
Pernarella M.; Piovesana R.; Matera C.; Faroni A.; Fiore M.; Dini L.; Reid A.J.; Dallanoce C.; Tata A.M.
Effects mediated by the ?7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells.
European journal of histochemistry (Testo stamp.): 61-70
Tocci P.; Cianfrocca R.; Sestito R.; Rosano L.; Di Castro V.; Blandino G.; Bagnato A.
Endothelin-1 axis fosters YAP-induced chemotherapy escape in ovarian cancer.
Cancer letters (Print): 84-95
Falvo, Elisabetta; Arcovito, Alessandro; Conti, Giamaica; Cipolla, Giuseppe; Pitea, Martina; Morea, Veronica; Damiani, Verena; Sala, Gianluca; Fracasso, Giulio; Ceci, Pierpaolo.
Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy.
Pharmaceutics
Naso, Francesco D.; Sterbini, Valentina; Crecca, Elena; Asteriti, Italia A.; Russo, Alessandra D.; Giubettini, Maria; Cundari, Enrico; Lindon, Catherine; Rosa, Alessandro; Guarguaglini, Giulia.
Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.
Cells
Perli, Elena; Pisano, Annalinda; Pignataro, Maria Gemma; Campese, Antonio Francesco; Pelullo, Maria; Genovese, Ilaria; de Turris, Valeria; Ghelli, Anna Maria; Cerbelli, Bruna; Giordano, Carla; Colotti, Gianni; Morea, Veronica; d'Amati, Giulia.
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects.
The FASEB journal
Tardani F.; Sarti S.; Sennato S.; Leo M.; Filetici P.; Casciardi S.; Schiavi P.G.; Bordi F.
Experimental Evidence of Single-Stranded DNA Adsorption on Multiwalled Carbon Nanotubes.
The journal of physical chemistry. B: 2514-2525
Antonella De Palma, Giulia Fanelli, Elisabetta Cretella, Veronica De Luca, Raffaele Antonio Palladino, Valentina Panzeri, Valentina Roffia, Michele Saliola, Pierluigi Mauri, Patrizia Filetici.
Gcn5p and Ubp8p Affect Protein Ubiquitylation and Cell Proliferation by Altering the Fermentative/Respiratory Flux Balance in Saccharomyces cerevisiae.
MBio: 1-16
Di Martile M.; Gabellini C.; Desideri M.; Matraxia M.; Farini V.; Valentini E.; Carradori S.; Ercolani C.; Buglioni S.; Secci D.; Andreazzoli M.; Del Bufalo D.; Trisciuoglio D.
Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells.
Journal of experimental & clinical cancer research (Online)103
Nardella, Caterina; Barile, Anna; di Salvo, Martino L.; Milano, Teresa; Pascarella, Stefano; Tramonti, Angela; Contestabile, Roberto.
Interaction of Bacillus subtilis GabR with the gabTD promoter: role of repeated sequences and effect of GABA in transcriptional activation.
The FEBS journal (Print)
Boyko, A. I.; Artiukhov, A. V.; Kaehne, T.; di Salvo, M. L.; Bonaccorsi di Patti, M. C.; Contestabile, R.; Tramonti, A.; Bunik, V. I.
Isoforms of the DHTKD1-Encoded 2-Oxoadipate Dehydrogenase, Identified in Animal Tissues, Are not Observed upon the Human DHTKD1 Expression in Bacterial or Yeast Systems.
Biochemistry (N.Y.): 920-929
Milazzo, Lisa; Exertier, Cecile; Becucci, Maurizio; Freda, Ida; Montemiglio, Linda Celeste; Savino, Carmelinda; Vallone, Beatrice; Smulevich, Giulietta.
Lack of orientation selectivity of the heme insertion in murine neuroglobin revealed by resonance Raman spectroscopy.
The FEBS journal (Print)
Marzi, Davide; Brunetti, Patrizia; Mele, Giovanni; Napoli, Nadia; Calo, Lorenzo; Spaziani, Erica; Matsui, Minami; De Panfilis, Simone; Costantino, Paolo; Serino, Giovanna; Cardarelli, Maura.
Light controls stamen elongation via cryptochromes, phytochromes and COP1 through HY5 and HYH.
Plant journal (Print)
Carla Sappino, ?a Ludovica Primitivo,?ae Martina De Angelis,ae Francesco Righi,a Federica Di Pietro,a Marika Iannoni,a Luciano Pilloni,b Stefano Vecchio Ciprioti,c Lorenza Suber, d Alessandra Ricelli e and Giuliana Righi e.
Linear b-amino alcohol catalyst anchored on functionalized magnetite nanoparticles for enantioselective addition of dialkylzinc to aromatic aldehydes+.
RSC advances: 29688-29695
Cristofaro, Ilaria; Limongi, Chiara; Piscopo, Paola; Crestini, Alessio; Guerriero, Claudia; Fiore, Mario; Conti, Luciano; Confaloni, Annamaria; Tata, Ada Maria.
M2 Receptor Activation Counteracts the Glioblastoma Cancer Stem Cell Response to Hypoxia Condition.
International journal of molecular sciences (Online)
Di Martile M.; Farini V.; Consonni F.M.; Trisciuoglio D.; Desideri M.; Valentini E.; D'aguanno S.; Tupone M.G.; Buglioni S.; Ercolani C.; Gallo E.; Amadio B.; Terrenato I.; Foddai M.L.; Sica A.; Del Bufalo D.
Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages.
Journal for ImmunoTherapy of Cancer
Tupone, Maria Grazia; D'Aguanno, Simona; Di Martile, Marta; Valentini, Elisabetta; Desideri, Marianna; Trisciuoglio, Daniela; Donzelli, Sara; Sacconi, Andrea; Buglioni, Simonetta; Ercolani, Cristiana; Biagioni, Alessio; Fibbi, Gabriella; Fattore, Luigi; Mancini, Rita; Ciliberto, Gennaro; Blandino, Giovanni; Del Bufalo, Donatella.
microRNA-378a-5p iS a novel positive regulator of melanoma progression.
Oncogenesis
Barile, Anna; Nogués, Isabel; di Salvo, Martino L.; Bunik, Victoria; Contestabile, Roberto; Tramonti, Angela.
Molecular characterization of pyridoxine 5'-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy.
Scientific reports (Nature Publishing Group)
Sabrina Venditti, Loredana Verdone, Anna Reale, Valerio Vetriani, Micaela Caserta, and Michele Zampieri.
Molecules of Silence. Effects of meditation on gene expression and epigenetics.
Frontiers in Psychology Frontiers media
Forte, Elena; Giuffrè, Alessandro; Huang, Li Shar; Berry, Edward A.; Borisov, Vitaliy B.
Nitric oxide does not inhibit but is metabolized by the cytochrome bcc-aa<inf>3</inf> supercomplex.
International journal of molecular sciences (Print): 1-12
Zwergel, Clemens; Fioravanti, Rossella; Stazi, Giulia; Sarno, Federica; Battistelli, Cecilia; Romanelli, Annalisa; Nebbioso, Angela; Mendes, Eduarda; Paulo, Alexandra; Strippoli, Raffaele; Tripodi, Marco; Pechalrieu, Dany; Arimondo, Paola B.; De Luca, Teresa; Del Bufalo, Donatella; Trisciuoglio, Daniela; Altucci, Lucia; Valente, Sergio; Mai, Antonello.
Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation.
Cancers (Basel)
Francioso A, Baseggio Conrado A, Blarzino C, Foppoli C, Montanari E, Dinarelli S, Giorgi A, Mosca L, Fontana M.
One- and Two-Electron Oxidations of ?-Amyloid 25-35 by Carbonate Radical Anion (CO 3o-) and Peroxymonocarbonate (HCO 4-): Role of Sulfur in Radical Reactions and Peptide Aggregation.
Molecules (Basel, Online)
Genovese, Ilaria; Carotti, Andrea; Ilari, Andrea; Fiorillo, Annarita; Battista, Theo; Colotti, Gianni; Ivarsson, Ylva.
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome.
Biochimica et biophysica acta. G, General subjects (Print)
Dattilo, Rosanna; Mottini, Carla; Camera, Emanuela; Lamolinara, Alessia; Auslander, Noam; Doglioni, Ginevra; Muscolini, Michela; Tang, Wei; Planque, Melanie; Ercolani, Cristiana; Buglioni, Simonetta; Manni, Isabella; Trisciuoglio, Daniela; Boe, Alessandra; Grande, Sveva; Luciani, Anna Maria; Iezzi, Manuela; Ciliberto, Gennaro; Ambs, Stefan; De Maria, Ruggero; Fendt, Sarah-Maria; Ruppin, Eytan; Cardone, Luca.
Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.
Cancer research (Chic. Ill.): 4087-4102
Scarabino D.; Peconi M.; Broggio E.; Gambina G.; Maggi E.; Armeli F.; Mantuano E.; Morello M.; Corbo R.M.; Businaro R.
Relationship between proinflammatory cytokines (Il-1beta, Il-18) and leukocyte telomere length in mild cognitive impairment and Alzheimer's disease.
Experimental gerontology
Cristina Bellisaia, Ilaria Sciamanna, Paola Rovella, Daniela Giovannini, Mirko Baranzini, Giusj Monia Pugliese, Mohammad Salik Zeya Ansari, Ciro Milite, Paola Sinibaldi-Vallebona, Roberto Cirilli, Gianluca Sbardella, Pietro Pichierri, Daniela Trisciuoglio, Patrizia Lavia, Annalucia Serafino, Corrado Spadafora.
Reverse transcriptase inhibitors promote the remodeling of nuclear architecture and induce autophagy in prostate cancer cells.
Cancer letters (Print): 133-145
Battista T.; Fiorillo A.; Chiarini V.; Genovese I.; Ilari A.; Colotti G.
Roles of sorcin in drug resistance in cancer: One protein, many mechanisms, for a novel potential anticancer drug target.
Cancers (Basel)
Carbone E.; De Felice M.; Di Rosa F.; D'Oro U.; Fontana S.; La Cava A.; Maio M.; Matarese G.; Racioppi L.; Ruggiero G.; Terrazzano G.
Serafino Zappacosta: An Enlightened Mentor and Educator.
Frontiers in immunology
Gabanella, Francesca; Onori, Annalisa; Ralli, Massimo; Greco, Antonio; Passananti, Claudio; Di Certo, Maria Grazia.
SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts.
Scientific reports (Nature Publishing Group)
Genovese I.; Giamogante F.; Barazzuol L.; Battista T.; Fiorillo A.; Vicario M.; D'Alessandro G.; Cipriani R.; Limatola C.; Rossi D.; Sorrentino V.; Poser E.; Mosca L.; Squitieri F.; Perluigi M.; Arena A.; van Petegem F.; Tito C.; Fazi F.; Giorgi C.; Cali T.; Ilari A.; Colotti G.
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.
Cell death and disease
Isabel Nogués , Angela Tramonti , Sebastiana Angelaccio , Milosz Ruszkowski , Bartosz Sekula , Roberto Contestabile.
Structural and kinetic properties of serine hydroxymethyltransferase from the halophytic cyanobacterium Aphanothece halophytica provide a rationale for salt tolerance.
International journal of biological macromolecules: 517-529
Colotti G.; Saccoliti F.; Gramiccia M.; Di Muccio T.; Prakash J.; Yadav S.; Dubey V.K.; Vistoli G.; Battista T.; Mocci S.; Fiorillo A.; Bibi A.; Madia V.N.; Messore A.; Costi R.; Di Santo R.; Ilari A.
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism.
Amino acids (Wien, Print)
Giovanna Costanzo, Judit E. Sponer, Jiri Sponer, Angela Cirigliano, Piero Benedetti, Valeria Giliberti, Raffaella Polito and Ernesto Di Mauro.
Sustainability and Chaos in the Abiotic Polymerization of 3',5' Cyclic Guanosine Monophosphate: The Role of Aggregation.
Chemistry (Weinh., Print): e2000011 1-e2000011 15
Rosanna Sestito, Roberta Cianfrocca, Piera Tocci, Laura Rosanò, Andrea Sacconi, Giovanni Blandino & Anna Bagnato.
Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer.
Communications biology
Battista T.; Colotti G.; Ilari A.; Fiorillo A.
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases.
Molecules (Basel, Online)
Garcia, Leyla; Batut, Berenice; Burke, Melissa L.; Kuzak, Mateusz; Psomopoulos, Fotis; Arcila, Ricardo; Attwood, Teresa K.; Beard, Niall; Carvalho-Silva, Denise; Dimopoulos, Alexandros C.; del Angel, Victoria Dominguez; Dumontier, Michel; Gurwitz, Kim T.; Krause, Roland; McQuilton, Peter; Le Pera, Loredana; Morgan, Sarah L.; Rauste, Paivi; Via, Allegra; Kahlem, Pascal; Rustici, Gabriella; van Gelder, Celia W. G.; Palagi, Patricia M.
Ten simple rules for making training materials FAIR.
PLOS computational biology (Online)
Colotti G.; Rinaldi T.
The central role of gut microbiota in drug metabolism and personalized medicine.
Future medicinal chemistry (Online): 1197-1200
Frappaolo, Anna; Karimpour-Ghahnavieh, Angela; Sechi, Stefano; Giansanti, Maria Grazia.
The Close Relationship between the Golgi Trafficking Machinery and Protein Glycosylation.
Cells
Luciano A.M.; Perciballi E.; Fiore M.; Del Bufalo D.; Tata A.M.
The combination of the m2 muscarinic receptor agonist and chemotherapy affects drug resistance in neuroblastoma cells.
International journal of molecular sciences (Print): 1-16
Esser, Charlotte; Boots, A. Mieke; Caignard, Anne; Ciraci, Ceren; Grcevic, Danka; Knapp, Sylvia; Montoya, Maria; Di Rosa, Francesca; Saksida, Tamara; Stravinskiene, Dovile; Deniz, Guennur.
The impact of COVID-19 lock-downs for European (female) immunologists - our views as members of the EFIS gender and diversity task force.
European Journal of Immunology
Contestabile, Roberto; di Salvo, Martino Luigi; Bunik, Victoria; Tramonti, Angela; Verni, Fiammetta.
The multifaceted role of vitamin B-6 in cancer: Drosophila as a model system to investigate DNA damage.
Open biology
Muñoz-Ruiz, Miguel; Pujol-Autonell, Irma; Rhys, Hefin; Long, Heather M.; Greco, Maria; Peakman, Mark; Tree, Tim; Hayday, Adrian C.; Di Rosa, Francesca.
Tracking immunodynamics by identification of S-G<inf>2</inf>/M-phase T cells in human peripheral blood.
Journal of autoimmunity (Print)
Ferrante C.; Batignani G.; Pontecorvo E.; Montemiglio L.C.; Vos M.H.; Scopigno T.
Ultrafast Dynamics and Vibrational Relaxation in Six-Coordinate Heme Proteins Revealed by Femtosecond Stimulated Raman Spectroscopy.
Journal of the American Chemical Society (Print): 2285-2292
Licursi, Valerio; Anzellotti, Silvia; Favaro, Jessica; Sineri, Serena; Carucci, Nicoletta; Cundari, Enrico; Fiore, Mario; Guarguaglini, Giulia; Pippa, Simone; Nisi, Paola S.; Vernì, Fiammetta; Biagioni, Stefano; Cacci, Emanuele; Amendola, Roberto; Lupo, Giuseppe; Negri, Rodolfo.
X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics.
Scientific reports (Nature Publishing Group)
Caterina Gulìa 1, Fabrizio Signore 2, Marco Gaffi 3, Silvia Gigli 4, Raffaella Votino 2, Roberto Nucciotti 1, Luca Bertacca 5, Simona Zaami 6, Alberto Baffa 2, Edoardo Santini 1, Alessandro Porrello 7 and Roberto Piergentili 8.
Y RNA: An Overview of Their Role as Potential Biomarkers and Molecular Targets in Human Cancers.
Cancers (Basel)
A dynamic COVID-19 immune signature includes associations with poor prognosis.
Nature medicine (Print): 1623-1635
Mascia A; Cirafici AM; Bongiovanni A; Colotti G; Lacerra G; Di Carlo M; Digilio FA; Liguori GL; Lanati A; Kisslinger A;.
A failure mode and effect analysis (FMEA)-based approach for risk assessment of scientific processes in non-regulated research laboratories.
Accreditation and quality assurance
Stefano Sechi, Anna Frappaolo,, Angela Karimpour-Ghahnavieh, Roberta Fraschini and Maria Grazia Giansanti.
A novel coordinated function of Myosin II with GOLPH3 controls centralspindlin localization during cytokinesis in Drosophila.
Journal of cell science (Online)
Di Rienzo L.; Milanetti E.; Testi C.; Montemiglio L.C.; Baiocco P.; Boffi A.; Ruocco G.
A novel strategy for molecular interfaces optimization: The case of Ferritin-Transferrin receptor interaction.
Computational and Structural Biotechnology Journal: 2678-2686
Ahmed Abdelbaki, H. Begum Akman, Marion Poteau, Rhys Grant, Olivier Gavet, Giulia Guarguaglini, Catherine Lindon.
AURKA destruction is decoupled from its activity at mitotic exit but essential to suppress interphase activity.
Journal of cell science (Online)
Kiraga,L., Cerutti,G., Braniewska,A., Strzemecki,D., Sas,Z., Boffi,A., Savino,C., Montemiglio,L.C., Turnham,D., Seaton,G., Bonamore,A., Clarkson,R., Dabkowski,A., Paisey,S.J., Taciak,B., Kucharzewska,P., Rygiel,T.P., Król,M.
Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice.
International journal of molecular sciences (Print): 4990-5006
Parry G.; Provart N.J.; Brady S.M.; Uzilday B.; Adams K.; Araujo W.; Aubourg S.; Baginsky S.; Bakker E.; Barenfaller K.; Batley J.; Beale M.; Beilstein M.; Belkhadir Y.; Mendel G.; Berardini T.; Bergelson J.; Blanco-Herrera F.; Brady S.; Braun H.-P.; Briggs S.; Brownfield L.; Cardarelli M.; Castellanos-Uribe M.; Coruzzi G.; Dassanayake M.; De Jaeger G.; Dilkes B.; Doherty C.; Ecker J.; Edger P.; Edwards D.; El Kasmi F.; Eriksson M.; Exposito-Alonso M.; Falter-Braun P.; Fernie A.; Ferro M.; Fiehn O.; Friesner J.; Greenham K.; Guo Y.; Hamann T.; Hancock A.; Hauser M.-T.; Heazlewood J.; Ho C.-H.; Horak H.; Huala E.; Hwang I.; Iuchi S.; Jaiswal P.; Jakobson L.; Jiang Y.; Jiao Y.; Jones A.; Kadota Y.; Khurana J.; Kliebenstein D.; Knee E.; Kobayashi M.; Koch M.; Krouk G.; Larson T.; Last R.; Lepiniec L.; Li S.; Lurin C.; Lysak M.; Maere S.; Malinowski R.; Maumus F.; May S.; Mayer K.; Mendoza-Cozatl D.; Mendoza-Poudereux I.; Luis Micol J.; Millar H.; Mock H.-P.; Mukhtar K.; Mukhtar S.; Murcha M.; Nakagami H.; Nakamura Y.; Nicolov L.; Nikolau B.; Nowack M.; Nunes-Nesi A.; Palmgren M.; Parry G.; Patron N.; Peck S.; Pedmale U.; Perrot-Rechenmann C.; Pieruschka R.; Pio-Beltran J.; Pires J.C.; Provart N.; Rajjou L.; Reiser L.; Rhee S.; Rigas S.; Rolland N.; Romanowski A.; Savaldi-Goldstein S.; Schmitz R.; Schulze W.; Seki M.; Shimizu K.K.; Slotkin K.; Small I.; Somers D.; Sozzani R.; Spillane C.; Srinivasan R.; Taylor N.; Tello-Ruiz M.-K.; Thelen J.; Tohge T.; Town C.; Toyoda T.; Uzilday B.; Walley J.; Ware D.; Weckwerth W.; Whitelegge J.; Wienkoop S.; Wright C.; Wrzaczek M.; Yamazaki M.; Yanovsky M.; Zarsky V.; Zhong X.; Van De Peer Y.; Van Wijk K.; Von Gillhaussen P.
Current status of the multinational Arabidopsis community.
Plant Direct
Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio.
Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
ACS medicinal chemistry letters: 977-983
Caroselli, Silvia; Zwergel, Clemens; Pirolli, Adele; Sabatino, Manuela; Xu, Zhanjie; Kirsch, Gilbert; Mai, Antonello; Colotti, Gianni; Altieri, Fabio; Canipari, Rita; Valente, Sergio; Ragno, Rino.
Discovery of the First Human Arylsulfatase A Reversible Inhibitor Impairing Mouse Oocyte Fertilization.
ACS chemical biology: 1349-1357
Parisi G.; Freda I.; Exertier C.; Cecchetti C.; Gugole E.; Cerutti G.; D'auria L.; Macone A.; Vallone B.; Savino C.; Montemiglio L.C.
Dissecting the cytochrome p450 olep substrate specificity: Evidence for a preferential substrate.
Biomolecules: 1-17
Di Rosa, Francesca.
Editorial: Serafino Zappacosta and the Ceppellini School: A Pioneer Model for Nurturing Education in Immunology.
Frontiers in immunology
Pernarella M.; Piovesana R.; Matera C.; Faroni A.; Fiore M.; Dini L.; Reid A.J.; Dallanoce C.; Tata A.M.
Effects mediated by the ?7 nicotinic acetylcholine receptor on cell proliferation and migration in rat adipose-derived stem cells.
European journal of histochemistry (Testo stamp.): 61-70
Tocci P.; Cianfrocca R.; Sestito R.; Rosano L.; Di Castro V.; Blandino G.; Bagnato A.
Endothelin-1 axis fosters YAP-induced chemotherapy escape in ovarian cancer.
Cancer letters (Print): 84-95
Falvo, Elisabetta; Arcovito, Alessandro; Conti, Giamaica; Cipolla, Giuseppe; Pitea, Martina; Morea, Veronica; Damiani, Verena; Sala, Gianluca; Fracasso, Giulio; Ceci, Pierpaolo.
Engineered Human Nanoferritin Bearing the Drug Genz-644282 for Cancer Therapy.
Pharmaceutics
Naso, Francesco D.; Sterbini, Valentina; Crecca, Elena; Asteriti, Italia A.; Russo, Alessandra D.; Giubettini, Maria; Cundari, Enrico; Lindon, Catherine; Rosa, Alessandro; Guarguaglini, Giulia.
Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.
Cells
Perli, Elena; Pisano, Annalinda; Pignataro, Maria Gemma; Campese, Antonio Francesco; Pelullo, Maria; Genovese, Ilaria; de Turris, Valeria; Ghelli, Anna Maria; Cerbelli, Bruna; Giordano, Carla; Colotti, Gianni; Morea, Veronica; d'Amati, Giulia.
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects.
The FASEB journal
Tardani F.; Sarti S.; Sennato S.; Leo M.; Filetici P.; Casciardi S.; Schiavi P.G.; Bordi F.
Experimental Evidence of Single-Stranded DNA Adsorption on Multiwalled Carbon Nanotubes.
The journal of physical chemistry. B: 2514-2525
Antonella De Palma, Giulia Fanelli, Elisabetta Cretella, Veronica De Luca, Raffaele Antonio Palladino, Valentina Panzeri, Valentina Roffia, Michele Saliola, Pierluigi Mauri, Patrizia Filetici.
Gcn5p and Ubp8p Affect Protein Ubiquitylation and Cell Proliferation by Altering the Fermentative/Respiratory Flux Balance in Saccharomyces cerevisiae.
MBio: 1-16
Di Martile M.; Gabellini C.; Desideri M.; Matraxia M.; Farini V.; Valentini E.; Carradori S.; Ercolani C.; Buglioni S.; Secci D.; Andreazzoli M.; Del Bufalo D.; Trisciuoglio D.
Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells.
Journal of experimental & clinical cancer research (Online)103
Nardella, Caterina; Barile, Anna; di Salvo, Martino L.; Milano, Teresa; Pascarella, Stefano; Tramonti, Angela; Contestabile, Roberto.
Interaction of Bacillus subtilis GabR with the gabTD promoter: role of repeated sequences and effect of GABA in transcriptional activation.
The FEBS journal (Print)
Boyko, A. I.; Artiukhov, A. V.; Kaehne, T.; di Salvo, M. L.; Bonaccorsi di Patti, M. C.; Contestabile, R.; Tramonti, A.; Bunik, V. I.
Isoforms of the DHTKD1-Encoded 2-Oxoadipate Dehydrogenase, Identified in Animal Tissues, Are not Observed upon the Human DHTKD1 Expression in Bacterial or Yeast Systems.
Biochemistry (N.Y.): 920-929
Milazzo, Lisa; Exertier, Cecile; Becucci, Maurizio; Freda, Ida; Montemiglio, Linda Celeste; Savino, Carmelinda; Vallone, Beatrice; Smulevich, Giulietta.
Lack of orientation selectivity of the heme insertion in murine neuroglobin revealed by resonance Raman spectroscopy.
The FEBS journal (Print)
Marzi, Davide; Brunetti, Patrizia; Mele, Giovanni; Napoli, Nadia; Calo, Lorenzo; Spaziani, Erica; Matsui, Minami; De Panfilis, Simone; Costantino, Paolo; Serino, Giovanna; Cardarelli, Maura.
Light controls stamen elongation via cryptochromes, phytochromes and COP1 through HY5 and HYH.
Plant journal (Print)
Carla Sappino, ?a Ludovica Primitivo,?ae Martina De Angelis,ae Francesco Righi,a Federica Di Pietro,a Marika Iannoni,a Luciano Pilloni,b Stefano Vecchio Ciprioti,c Lorenza Suber, d Alessandra Ricelli e and Giuliana Righi e.
Linear b-amino alcohol catalyst anchored on functionalized magnetite nanoparticles for enantioselective addition of dialkylzinc to aromatic aldehydes+.
RSC advances: 29688-29695
Cristofaro, Ilaria; Limongi, Chiara; Piscopo, Paola; Crestini, Alessio; Guerriero, Claudia; Fiore, Mario; Conti, Luciano; Confaloni, Annamaria; Tata, Ada Maria.
M2 Receptor Activation Counteracts the Glioblastoma Cancer Stem Cell Response to Hypoxia Condition.
International journal of molecular sciences (Online)
Di Martile M.; Farini V.; Consonni F.M.; Trisciuoglio D.; Desideri M.; Valentini E.; D'aguanno S.; Tupone M.G.; Buglioni S.; Ercolani C.; Gallo E.; Amadio B.; Terrenato I.; Foddai M.L.; Sica A.; Del Bufalo D.
Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages.
Journal for ImmunoTherapy of Cancer
Tupone, Maria Grazia; D'Aguanno, Simona; Di Martile, Marta; Valentini, Elisabetta; Desideri, Marianna; Trisciuoglio, Daniela; Donzelli, Sara; Sacconi, Andrea; Buglioni, Simonetta; Ercolani, Cristiana; Biagioni, Alessio; Fibbi, Gabriella; Fattore, Luigi; Mancini, Rita; Ciliberto, Gennaro; Blandino, Giovanni; Del Bufalo, Donatella.
microRNA-378a-5p iS a novel positive regulator of melanoma progression.
Oncogenesis
Barile, Anna; Nogués, Isabel; di Salvo, Martino L.; Bunik, Victoria; Contestabile, Roberto; Tramonti, Angela.
Molecular characterization of pyridoxine 5'-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy.
Scientific reports (Nature Publishing Group)
Sabrina Venditti, Loredana Verdone, Anna Reale, Valerio Vetriani, Micaela Caserta, and Michele Zampieri.
Molecules of Silence. Effects of meditation on gene expression and epigenetics.
Frontiers in Psychology Frontiers media
Forte, Elena; Giuffrè, Alessandro; Huang, Li Shar; Berry, Edward A.; Borisov, Vitaliy B.
Nitric oxide does not inhibit but is metabolized by the cytochrome bcc-aa<inf>3</inf> supercomplex.
International journal of molecular sciences (Print): 1-12
Zwergel, Clemens; Fioravanti, Rossella; Stazi, Giulia; Sarno, Federica; Battistelli, Cecilia; Romanelli, Annalisa; Nebbioso, Angela; Mendes, Eduarda; Paulo, Alexandra; Strippoli, Raffaele; Tripodi, Marco; Pechalrieu, Dany; Arimondo, Paola B.; De Luca, Teresa; Del Bufalo, Donatella; Trisciuoglio, Daniela; Altucci, Lucia; Valente, Sergio; Mai, Antonello.
Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation.
Cancers (Basel)
Francioso A, Baseggio Conrado A, Blarzino C, Foppoli C, Montanari E, Dinarelli S, Giorgi A, Mosca L, Fontana M.
One- and Two-Electron Oxidations of ?-Amyloid 25-35 by Carbonate Radical Anion (CO 3o-) and Peroxymonocarbonate (HCO 4-): Role of Sulfur in Radical Reactions and Peptide Aggregation.
Molecules (Basel, Online)
Genovese, Ilaria; Carotti, Andrea; Ilari, Andrea; Fiorillo, Annarita; Battista, Theo; Colotti, Gianni; Ivarsson, Ylva.
Profiling calcium-dependent interactions between Sorcin and intrinsically disordered regions of human proteome.
Biochimica et biophysica acta. G, General subjects (Print)
Dattilo, Rosanna; Mottini, Carla; Camera, Emanuela; Lamolinara, Alessia; Auslander, Noam; Doglioni, Ginevra; Muscolini, Michela; Tang, Wei; Planque, Melanie; Ercolani, Cristiana; Buglioni, Simonetta; Manni, Isabella; Trisciuoglio, Daniela; Boe, Alessandra; Grande, Sveva; Luciani, Anna Maria; Iezzi, Manuela; Ciliberto, Gennaro; Ambs, Stefan; De Maria, Ruggero; Fendt, Sarah-Maria; Ruppin, Eytan; Cardone, Luca.
Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.
Cancer research (Chic. Ill.): 4087-4102
Scarabino D.; Peconi M.; Broggio E.; Gambina G.; Maggi E.; Armeli F.; Mantuano E.; Morello M.; Corbo R.M.; Businaro R.
Relationship between proinflammatory cytokines (Il-1beta, Il-18) and leukocyte telomere length in mild cognitive impairment and Alzheimer's disease.
Experimental gerontology
Cristina Bellisaia, Ilaria Sciamanna, Paola Rovella, Daniela Giovannini, Mirko Baranzini, Giusj Monia Pugliese, Mohammad Salik Zeya Ansari, Ciro Milite, Paola Sinibaldi-Vallebona, Roberto Cirilli, Gianluca Sbardella, Pietro Pichierri, Daniela Trisciuoglio, Patrizia Lavia, Annalucia Serafino, Corrado Spadafora.
Reverse transcriptase inhibitors promote the remodeling of nuclear architecture and induce autophagy in prostate cancer cells.
Cancer letters (Print): 133-145
Battista T.; Fiorillo A.; Chiarini V.; Genovese I.; Ilari A.; Colotti G.
Roles of sorcin in drug resistance in cancer: One protein, many mechanisms, for a novel potential anticancer drug target.
Cancers (Basel)
Carbone E.; De Felice M.; Di Rosa F.; D'Oro U.; Fontana S.; La Cava A.; Maio M.; Matarese G.; Racioppi L.; Ruggiero G.; Terrazzano G.
Serafino Zappacosta: An Enlightened Mentor and Educator.
Frontiers in immunology
Gabanella, Francesca; Onori, Annalisa; Ralli, Massimo; Greco, Antonio; Passananti, Claudio; Di Certo, Maria Grazia.
SMN protein promotes membrane compartmentalization of ribosomal protein S6 transcript in human fibroblasts.
Scientific reports (Nature Publishing Group)
Genovese I.; Giamogante F.; Barazzuol L.; Battista T.; Fiorillo A.; Vicario M.; D'Alessandro G.; Cipriani R.; Limatola C.; Rossi D.; Sorrentino V.; Poser E.; Mosca L.; Squitieri F.; Perluigi M.; Arena A.; van Petegem F.; Tito C.; Fazi F.; Giorgi C.; Cali T.; Ilari A.; Colotti G.
Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.
Cell death and disease
Isabel Nogués , Angela Tramonti , Sebastiana Angelaccio , Milosz Ruszkowski , Bartosz Sekula , Roberto Contestabile.
Structural and kinetic properties of serine hydroxymethyltransferase from the halophytic cyanobacterium Aphanothece halophytica provide a rationale for salt tolerance.
International journal of biological macromolecules: 517-529
Colotti G.; Saccoliti F.; Gramiccia M.; Di Muccio T.; Prakash J.; Yadav S.; Dubey V.K.; Vistoli G.; Battista T.; Mocci S.; Fiorillo A.; Bibi A.; Madia V.N.; Messore A.; Costi R.; Di Santo R.; Ilari A.
Structure-guided approach to identify a novel class of anti-leishmaniasis diaryl sulfide compounds targeting the trypanothione metabolism.
Amino acids (Wien, Print)
Giovanna Costanzo, Judit E. Sponer, Jiri Sponer, Angela Cirigliano, Piero Benedetti, Valeria Giliberti, Raffaella Polito and Ernesto Di Mauro.
Sustainability and Chaos in the Abiotic Polymerization of 3',5' Cyclic Guanosine Monophosphate: The Role of Aggregation.
Chemistry (Weinh., Print): e2000011 1-e2000011 15
Rosanna Sestito, Roberta Cianfrocca, Piera Tocci, Laura Rosanò, Andrea Sacconi, Giovanni Blandino & Anna Bagnato.
Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer.
Communications biology
Battista T.; Colotti G.; Ilari A.; Fiorillo A.
Targeting trypanothione reductase, a key enzyme in the redox trypanosomatid metabolism, to develop new drugs against leishmaniasis and trypanosomiases.
Molecules (Basel, Online)
Garcia, Leyla; Batut, Berenice; Burke, Melissa L.; Kuzak, Mateusz; Psomopoulos, Fotis; Arcila, Ricardo; Attwood, Teresa K.; Beard, Niall; Carvalho-Silva, Denise; Dimopoulos, Alexandros C.; del Angel, Victoria Dominguez; Dumontier, Michel; Gurwitz, Kim T.; Krause, Roland; McQuilton, Peter; Le Pera, Loredana; Morgan, Sarah L.; Rauste, Paivi; Via, Allegra; Kahlem, Pascal; Rustici, Gabriella; van Gelder, Celia W. G.; Palagi, Patricia M.
Ten simple rules for making training materials FAIR.
PLOS computational biology (Online)
Colotti G.; Rinaldi T.
The central role of gut microbiota in drug metabolism and personalized medicine.
Future medicinal chemistry (Online): 1197-1200
Frappaolo, Anna; Karimpour-Ghahnavieh, Angela; Sechi, Stefano; Giansanti, Maria Grazia.
The Close Relationship between the Golgi Trafficking Machinery and Protein Glycosylation.
Cells
Luciano A.M.; Perciballi E.; Fiore M.; Del Bufalo D.; Tata A.M.
The combination of the m2 muscarinic receptor agonist and chemotherapy affects drug resistance in neuroblastoma cells.
International journal of molecular sciences (Print): 1-16
Esser, Charlotte; Boots, A. Mieke; Caignard, Anne; Ciraci, Ceren; Grcevic, Danka; Knapp, Sylvia; Montoya, Maria; Di Rosa, Francesca; Saksida, Tamara; Stravinskiene, Dovile; Deniz, Guennur.
The impact of COVID-19 lock-downs for European (female) immunologists - our views as members of the EFIS gender and diversity task force.
European Journal of Immunology
Contestabile, Roberto; di Salvo, Martino Luigi; Bunik, Victoria; Tramonti, Angela; Verni, Fiammetta.
The multifaceted role of vitamin B-6 in cancer: Drosophila as a model system to investigate DNA damage.
Open biology
Muñoz-Ruiz, Miguel; Pujol-Autonell, Irma; Rhys, Hefin; Long, Heather M.; Greco, Maria; Peakman, Mark; Tree, Tim; Hayday, Adrian C.; Di Rosa, Francesca.
Tracking immunodynamics by identification of S-G<inf>2</inf>/M-phase T cells in human peripheral blood.
Journal of autoimmunity (Print)
Ferrante C.; Batignani G.; Pontecorvo E.; Montemiglio L.C.; Vos M.H.; Scopigno T.
Ultrafast Dynamics and Vibrational Relaxation in Six-Coordinate Heme Proteins Revealed by Femtosecond Stimulated Raman Spectroscopy.
Journal of the American Chemical Society (Print): 2285-2292
Licursi, Valerio; Anzellotti, Silvia; Favaro, Jessica; Sineri, Serena; Carucci, Nicoletta; Cundari, Enrico; Fiore, Mario; Guarguaglini, Giulia; Pippa, Simone; Nisi, Paola S.; Vernì, Fiammetta; Biagioni, Stefano; Cacci, Emanuele; Amendola, Roberto; Lupo, Giuseppe; Negri, Rodolfo.
X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics.
Scientific reports (Nature Publishing Group)
Caterina Gulìa 1, Fabrizio Signore 2, Marco Gaffi 3, Silvia Gigli 4, Raffaella Votino 2, Roberto Nucciotti 1, Luca Bertacca 5, Simona Zaami 6, Alberto Baffa 2, Edoardo Santini 1, Alessandro Porrello 7 and Roberto Piergentili 8.
Y RNA: An Overview of Their Role as Potential Biomarkers and Molecular Targets in Human Cancers.
Cancers (Basel)