• Istituto di Biologia e Patologia Molecolari

Ahmed Abdelbaki, H. Begum Akman, Marion Poteau, Rhys Grant, Olivier Gavet, Giulia Guarguaglini, Catherine Lindon.
AURKA destruction is decoupled from its activity at mitotic exit but essential to suppress interphase activity.
Journal of cell science (Online)

Kiraga,?., Cerutti,G., Braniewska,A., Strzemecki,D., Sas,Z., Boffi,A., Savino,C., Montemiglio,L.C., Turnham,D., Seaton,G., Bonamore,A., Clarkson,R., Dabkowski,A., Paisey,S.J., Taciak,B., Kucharzewska,P., Rygiel,T.P., Król,M.
Biodistribution PET/CT study of hemoglobin-DFO-89Zr complex in healthy and lung tumor-bearing mice.
International journal of molecular sciences (Print): 4990-5006

Romanelli, Annalisa; Stazi, Giulia; Fioravanti, Rossella; Zwergel, Clemens; Di Bello, Elisabetta; Pomella, Silvia; Perrone, Clara; Battistelli, Cecilia; Strippoli, Raffaele; Tripodi, Marco; del Bufalo, Donatella; Rota, Rossella; Trisciuoglio, Daniela; Mai, Antonello; Valente, Sergio.
Design of First-in-Class Dual EZH2/HDAC Inhibitor: Biochemical Activity and Biological Evaluation in Cancer Cells.
ACS medicinal chemistry letters: 977-983

Naso, Francesco D.; Sterbini, Valentina; Crecca, Elena; Asteriti, Italia A.; Russo, Alessandra D.; Giubettini, Maria; Cundari, Enrico; Lindon, Catherine; Rosa, Alessandro; Guarguaglini, Giulia.
Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.
Cells

Perli, Elena; Pisano, Annalinda; Pignataro, Maria Gemma; Campese, Antonio Francesco; Pelullo, Maria; Genovese, Ilaria; de Turris, Valeria; Ghelli, Anna Maria; Cerbelli, Bruna; Giordano, Carla; Colotti, Gianni; Morea, Veronica; d'Amati, Giulia.
Exogenous peptides are able to penetrate human cell and mitochondrial membranes, stabilize mitochondrial tRNA structures, and rescue severe mitochondrial defects.
The FASEB journal

Tardani F.; Sarti S.; Sennato S.; Leo M.; Filetici P.; Casciardi S.; Schiavi P.G.; Bordi F.
Experimental Evidence of Single-Stranded DNA Adsorption on Multiwalled Carbon Nanotubes.
The journal of physical chemistry. B: 2514-2525

Verrico A.; Rovella P.; Di Francesco L.; Damizia M.; Staid D.S.; Le Pera L.; Schinina M.E.; Lavia P.
Importin-?/karyopherin-?1 modulates mitotic microtubule function and taxane sensitivity in cancer cells via its nucleoporin-binding region.
Oncogene (Basingstoke): 454-468

Di Martile M.; Gabellini C.; Desideri M.; Matraxia M.; Farini V.; Valentini E.; Carradori S.; Ercolani C.; Buglioni S.; Secci D.; Andreazzoli M.; Del Bufalo D.; Trisciuoglio D.
Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells.
Journal of experimental & clinical cancer research (Online)103

Nardella, Caterina; Barile, Anna; di Salvo, Martino L.; Milano, Teresa; Pascarella, Stefano; Tramonti, Angela; Contestabile, Roberto.
Interaction of Bacillus subtilis GabR with the gabTD promoter: role of repeated sequences and effect of GABA in transcriptional activation.
The FEBS journal (Print)

Milazzo, Lisa; Exertier, Cecile; Becucci, Maurizio; Freda, Ida; Montemiglio, Linda Celeste; Savino, Carmelinda; Vallone, Beatrice; Smulevich, Giulietta.
Lack of orientation selectivity of the heme insertion in murine neuroglobin revealed by resonance Raman spectroscopy.
The FEBS journal (Print)

Marzi, Davide; Brunetti, Patrizia; Mele, Giovanni; Napoli, Nadia; Calo, Lorenzo; Spaziani, Erica; Matsui, Minami; De Panfilis, Simone; Costantino, Paolo; Serino, Giovanna; Cardarelli, Maura.
Light controls stamen elongation via cryptochromes, phytochromes and COP1 through HY5 and HYH.
Plant journal (Print)

Tupone, Maria Grazia; D'Aguanno, Simona; Di Martile, Marta; Valentini, Elisabetta; Desideri, Marianna; Trisciuoglio, Daniela; Donzelli, Sara; Sacconi, Andrea; Buglioni, Simonetta; Ercolani, Cristiana; Biagioni, Alessio; Fibbi, Gabriella; Fattore, Luigi; Mancini, Rita; Ciliberto, Gennaro; Blandino, Giovanni; Del Bufalo, Donatella.
microRNA-378a-5p iS a novel positive regulator of melanoma progression.
Oncogenesis

Zwergel, Clemens; Fioravanti, Rossella; Stazi, Giulia; Sarno, Federica; Battistelli, Cecilia; Romanelli, Annalisa; Nebbioso, Angela; Mendes, Eduarda; Paulo, Alexandra; Strippoli, Raffaele; Tripodi, Marco; Pechalrieu, Dany; Arimondo, Paola B.; De Luca, Teresa; Del Bufalo, Donatella; Trisciuoglio, Daniela; Altucci, Lucia; Valente, Sergio; Mai, Antonello.
Novel quinoline compounds active in cancer cells through coupled DNA methyltransferase inhibition and degradation.
Cancers (Basel)

Scarabino D.; Peconi M.; Broggio E.; Gambina G.; Maggi E.; Armeli F.; Mantuano E.; Morello M.; Corbo R.M.; Businaro R.
Relationship between proinflammatory cytokines (Il-1beta, Il-18) and leukocyte telomere length in mild cognitive impairment and Alzheimer's disease.
Experimental gerontology

Cristina Bellisaia, Ilaria Sciamanna, Paola Rovella, Daniela Giovannini, Mirko Baranzini, Giusj Monia Pugliese, Mohammad Salik Zeya Ansari, Ciro Milite, Paola Sinibaldi-Vallebona, Roberto Cirilli, Gianluca Sbardella, Pietro Pichierri, Daniela Trisciuoglio, Patrizia Lavia, Annalucia Serafino, Corrado Spadafora.
Reverse transcriptase inhibitors promote the remodeling of nuclear architecture and induce autophagy in prostate cancer cells.
Cancer letters (Print): 133-145

Isabel Nogués , Angela Tramonti , Sebastiana Angelaccio , Milosz Ruszkowski , Bartosz Sekula , Roberto Contestabile.
Structural and kinetic properties of serine hydroxymethyltransferase from the halophytic cyanobacterium Aphanothece halophytica provide a rationale for salt tolerance.
International journal of biological macromolecules: 517-529

Contestabile, Roberto; di Salvo, Martino Luigi; Bunik, Victoria; Tramonti, Angela; Verni, Fiammetta.
The multifaceted role of vitamin B-6 in cancer: Drosophila as a model system to investigate DNA damage.
Open biology

Licursi, Valerio; Anzellotti, Silvia; Favaro, Jessica; Sineri, Serena; Carucci, Nicoletta; Cundari, Enrico; Fiore, Mario; Guarguaglini, Giulia; Pippa, Simone; Nisi, Paola S.; Vernì, Fiammetta; Biagioni, Stefano; Cacci, Emanuele; Amendola, Roberto; Lupo, Giuseppe; Negri, Rodolfo.
X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics.
Scientific reports (Nature Publishing Group)

Caterina Gulìa 1, Fabrizio Signore 2, Marco Gaffi 3, Silvia Gigli 4, Raffaella Votino 2, Roberto Nucciotti 1, Luca Bertacca 5, Simona Zaami 6, Alberto Baffa 2, Edoardo Santini 1, Alessandro Porrello 7 and Roberto Piergentili 8.
Y RNA: An Overview of Their Role as Potential Biomarkers and Molecular Targets in Human Cancers.
Cancers (Basel)

Julia Mathlin, Loredana Le Pera, Teresa Colombo.
A Census and Categorization Method of Epitranscriptomic Marks.
International journal of molecular sciences (Online)

Sechi S.; Frappaolo A.; Karimpour-Ghahnavieh A.; Piergentili R.; Giansanti M.G.
Oncogenic Roles of GOLPH3 in the Physiopathology of Cancer.
International journal of molecular sciences (Online)

Fabrizio Signore, Caterina Gulìa, Raffaella Votino, Vincenzo De Leo, Simona Zaami, Lorenza Putignani, Silvia Gigli, Edoardo Santini, Luca Bertacca, Alessandro Porrello, Roberto Piergentili.
The Role of Number of Copies, Structure, Behavior and Copy Number Variations (CNV) of the Y Chromosome in Male Infertility.
Genes (Basel)

Roberto Piergentili.
Y RNA in cell cycle progression and cancer.
Atlas of genetics and cytogenetics in oncology and haematology

Carla Sappino, ?a Ludovica Primitivo,?ae Martina De Angelis,ae Francesco Righi,a Federica Di Pietro,a Marika Iannoni,a Luciano Pilloni,b Stefano Vecchio Ciprioti,c Lorenza Suber, d Alessandra Ricelli e and Giuliana Righi e. 
Linear b-amino alcohol catalyst anchored on functionalized magnetite nanoparticles for enantioselective addition of dialkylzinc to aromatic aldehydes+. 
RSC advances: 29688-29695

Sabrina Venditti, Loredana Verdone, Anna Reale, Valerio Vetriani, Micaela Caserta, and Michele Zampieri. 
Molecules of Silence. Effects of meditation on gene expression and epigenetics. 
Frontiers in Psychology Frontiers media

E. Lattuada, M. Leo, D. Caprara, L. Salvatori, A. Stoppacciaro, F. Sciortino, P. Filetici
DNA-GEL, Novel Nanomaterial for Biomedical Applications and Delivery of Bioactive Molecules
Frontiers in Pharmacology 11, 1345 sept.2020

A. De Palma, G. Fanelli, E. Cretella, V. De Luca, RA. Palladino, V. Panzeri, V. Roffia, M. Saliola, PL. Mauri, P. Filetici
Gcn5p and Ubp8p Affect Protein Ubiquitylation and Cell Proliferation by Altering the Fermentative/Respiratory Flux Balance in Saccharomyces cerevisiae
mBio 11 (4) july 2020