• Istituto di Biologia e Patologia Molecolari

IBPM Highlights

12/03/2019


13/02/2019
Alternanza Scuola-Lavoro: novanta ore per studiare antibiotici e SLA

Articolo di rassegna stampa


 


16/01/2019

During mitotic division genomic DNA is equally partitioned between the daughter cells, and several cellular machineries are reorganized to ensure faithful chromosome segregation. For example, cellular processes such as transcription and mRNA processing (“splicing”) are shut down during mitosis. The work by Pellacani et al. shows that two splicing factors, Sf3A2 e Prp31, are not inactive during mitosis but directly mediate proper kinetochore- microtubule interactions. These findings open the way to future research aimed at identifying new “moonlighting proteins” involved in both nuclear processes occurring during interphase and regulation of mitosis. An accurate understanding of mitosis at the molecular level is crucial to elucidate the mechanisms of tumorigenesis and develop new anti-cancer therapies.




DUCHENNE DISTROPHY: ENGINEERING A NEW ARTIFICIAL GENE FOR THERAPEUTIC PURPOSES

BBA


Documents: Press Review



PLANT MOCLECULAR BIOLOGY
"FRESH AS AN EXITRON": A NEW GROWTH REGULATORY MECHANISM DISCOVERED IN PLANTS
see Editorial Highlight in Plant Cell
 


Plant Cell
 
Documents: Plant Cell Editorial Highlight