• Istituto di Biologia e Patologia Molecolari

ANNA FRAPPAOLO

EDUCATION
• February 6, 2017 PhD Degree in Life Science (XXIX cycle), Classification: Excellent; “Sapienza” Università di Roma,
• October 3, 2013 Second Level degree cum laude in Genetics and Molecular Biology, “Sapienza” Università di Roma, under the supervision of Dr. Maria Grazia Giansanti.
• December 13, 2011 First Level degree cum laude in Biological Sciences, “Sapienza” Università di Roma. 

POST-LAUREAM EXPERIENCE
• April 2020 Postdoctoral fellow at IBPM-CNR; Project title: “Golgi phosphoprotein 3 and membrane trafficking in cytokinesis and cell proliferation”; project funded by AIRC (PI, Dr. Giansanti).
• March 2017- February 2020 CNR-IBPM Researcher, III level (Dr. Giansanti Lab); TD supported by FIRC/AIRC fellowship; research project “The oncoprotein GOLPH3 and membrane trafficking during cytokinesis”
• November 2013- February 2017 PhD student in Dr. Maria Grazia Giansanti lab; research activity focused on the oncoprotein GOLPH3 and membrane trafficking during Drosophila cytokinesis.
• January 2012-October 2013 Internship (laurea magistralis/Second level degree in Genetics and Molecular Biology) under the supervision of Dr. Maria Grazia Giansanti. Cytological and molecular characterization of sauron and doublefault, two mutants affecting male meiosis in Drosophila.
• June 2011-December 2011 Internship (First level degree in Biological Science) under the supervision of Dr. Maria Grazia Giansanti. Cytological characterization of doublefault, a mutant affecting male meiosis in Drosophila. 1. Sechi S., Frappaolo A. *, Karimpour-Ghahnavieh A., Piergentili R., Giansanti M.G. Oncogenic Roles of GOLPH3 in the Physiopathology of Cancer. Int J Mol Sci. 2020. 21. pii: E933.
* primo autore in condivisione
2. Sechi S., Frappaolo A. *, Karimpour-Ghahnavieh A., Gottardo M., Burla R., Di Francesco L., Szafer-Glusman E., Schininà E., Fuller M.T., Saggio I., Riparbelli M.G., Callaini G., Giansanti M.G. Drosophila Doublefault protein coordinates multiple events during male meiosis by controlling mRNA translation. Development. 2019.146. pii: dev183053.
* primo autore in condivisione
3. Frappaolo A., Sechi S., Kumagai T., Karimpour-Ghahnavieh A., Tiemeyer M., Giansanti M.G. Modeling Congenital Disorders of N-Linked Glycoprotein Glycosylation in Drosophila melanogaster. Frontiers in Genetics. 2018. 9:436.
4. Frappaolo A., Sechi S., Kumagai T., Robinson S., Fraschini R., Karimpour-Ghahnavieh A., Belloni G., Piergentili R., Tiemeyer K.H., Tiemeyer M., Giansanti M.G. COG7 deficiency in Drosophila generates multifaceted developmental, behavioral and protein glycosylation phenotypes. Journal of Cell Science. 2017. 130: 3637-3649.
5. Sechi S., Frappaolo A.*, Fraschini R., Capalbo L., Gottardo M., Belloni G, Glover D.M., Wainman A., Giansanti M.G. Rab1 interacts with GOLPH3 and controls Golgi structure and contractile ring constriction during cytokinesis in Drosophila melanogaster. Open Biology. 2017. 7. pii: 160257.
* primo autore in condivisione
6. Frappaolo A., Sechi S., Belloni G., Piergentili R., Giansanti M.G. Visualization of cleavage furrow proteins in fixed dividing spermatocytes. Methods in Cell Biology. 2017; 137:85-103.
7. Giansanti M.G., Vanderleest T.E., Jewett C.E., Sechi S., Frappaolo A., Fabian L., Robinett C.C., Brill J.A., Loerke D., Fuller M.T., Blankenship J.T. Exocyst-Dependent Membrane Addition Is Required for Anaphase Cell Elongation and Cytokinesis in Drosophila. PLoS Genetics. 2015. 11: e1005632.
8. Sechi S., Frappaolo A.*, Belloni G., Colotti G., Giansanti M.G. The multiple cellular functions of the oncoprotein Golgi phosphoprotein 3. Oncotarget. 2015. 6:3493-3506.
* primo autore in condivisione
9. Sechi S., Frappaolo A., Belloni G., Giansanti M.G. The roles of the oncoprotein GOLPH3 in contractile ring assembly and membrane trafficking during cytokinesis. Biochemical Society Transactions. 2015. 43:117-121.
10. Sechi S., Colotti G., Belloni G., Mattei V., Frappaolo A., Raffa G.D., Fuller M.T., Giansanti M.G. GOLPH3 is essential for contractile ring formation and Rab11 localization to the cleavage site during cytokinesis in Drosophila melanogaster. PLoS Genetics. 2014.10: e1004305.
11. Giansanti M.G., Sechi S., Frappaolo A., Belloni G. and Piergentili R. Cytokinesis in Drosophila male meiosis. Spermatogenesis. 2012. 2:185–196.