A first-in-class non-cytotoxic nanocarrier based on a recombinant human ferritin boosts targeted therapy, chemotherapy and immunotherapy.
Tisci G, Rajsiglova L, Bibbo S, Ziccheddu G, Ricciardi E, Falvo E, De Laurenzi V, Sala G, Capone E, Colotti G, Arcovito A, Giacon N, Makovicky P, Sushytskyi L, Lukac P, Vannucci L, Giacomini P, Ceci P.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2025;309(Pt 1). doi: 10.1016/j.ijbiomac.2025.142843.

A New Perspective on the Arrival of the Eastern Mediterranean Genetic Influx in Central Italy Before the Onset of the Roman Empire.
Ravasini F, Conati Barbaro C, Scheib CL, Tambets K, Metspalu M, Cruciani F, Trombetta B, D'Atanasio E.
GENOME BIOLOGY AND EVOLUTION. 2025;17(8). doi: 10.1093/gbe/evaf149.

Acute chromatin decompaction stiffens the nucleus as revealed by nanopillar-induced nuclear deformation in cells.
Mitra A, Cutiongco MFA, Burla R, Zeng Y, Na Q, Kong M, Vinod B, Nai MH, Hubner B, Ludwig A, Lim CT, Shivashankar GV, Saggio I, Zhao W.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2025;122(19). doi: 10.1073/pnas.2416659122.

Alcohol Consumption and Autoimmune Diseases.
Terracina S, Caronti B, Lucarelli M, Francati S, Piccioni MG, Tarani L, Ceccanti M, Caserta M, Verdone L, Venditti S, Fiore M, Ferraguti G.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2025;26(2). doi: 10.3390/ijms26020845.

An Immunosenescent CD8+ T Cell Subset in Patients with Axial Spondyloarthritis and Psoriatic Arthritis Links Spontaneous Motility to Telomere Shortening and Dysfunction.
Paldino G, Tedeschi V, Proganò V, Salvati E, Licursi V, Vertecchi E, Bivolaru AL, Molteni E, Scrivo R, Congia M, Cauli A, Caccavale R, Paroli M, Kunkl M, Tuosto L, Sorrentino R, Fiorillo MT.
ARTHRITIS & RHEUMATOLOGY. 2025;77(7). doi: 10.1002/art.43109.

Analysis of microRNA-transcript regulatory networks in the hippocampus of the BTBR mouse model of autism.
Gasparini S, Licursi V, Rinaldi A, Ricceri L, Scattoni ML, Presutti C, Mannironi C.
FRONTIERS IN CELLULAR NEUROSCIENCE. 2025;19. doi: 10.3389/fncel.2025.1676316.

Aspergillus in Italian Pistachios: Characterization and Detection of Major Aflatoxigenic Species With a Loop-Mediated Isothermal Amplification Assay.
Mellikeche W, Ricelli A, Abukhmaish M, Caracciolo R, Gallo M, Casini C, Colelli G, D'Onghia AM, Valentini F.
FOOD SCIENCE & NUTRITION. 2025;13(11). doi: 10.1002/fsn3.71146.

Bone Adhered Sediments as a Source of Target and Environmental DNA and Proteins.
de-Dios T, Bonucci B, Barbieri R, Kushniarevich A, D'Atanasio E, Dittmar J, Cessford C, Solnik A, Robb JE, Warinner C, Oras E, Scheib CL.
MOLECULAR BIOLOGY AND EVOLUTION. 2025;42(9). doi: 10.1093/molbev/msaf202.

Building a Hand-Curated ceRNET for Endometrial Cancer, Striving for Clinical as Well as Medicolegal Soundness: A Systematic Review.
Piergentili R, Sechi S, De Paola L, Zaami S, Marinelli E.
NON-CODING RNA. 2025;11(3). doi: 10.3390/ncrna11030034.

canSAR 2024-an update to the public drug discovery knowledgebase.
Gingrich PW, Chitsazi R, Biswas A, Jiang C, Zhao L, Tym JE, Brammer KM, Jun L, Shu Z, Maxwell DS, Tacy JA, Mica IL, Darkoh M, di Micco P, Russell KP, Workman P, Al-Lazikani B.
NUCLEIC ACIDS RESEARCH. 2025;53(D1). doi: 10.1093/nar/gkae1050.

Caspase-8 is a novel modulator of Homologous Recombination Repair in response to ionizing radiations.
Ferri A, Contadini C, Di Girolamo C, Cirotti C, Fiscon G, Paci P, Marzullo M, Pia Gentileschi M, Yamamoto T, Strauss R, Del Bufalo D, Ciapponi L, Barilà D.
CANCER LETTERS. 2025. doi: 10.1101/2025.05.26.656091.

cGAS-STING are responsible for premature aging of telomerase-deficient zebrafish.
Serifoglu N, Allavena G, Lopes-Bastos B, Marzullo M, Marques A, Colibert P, Bousounis P, Trompouki E, Ferreira MG.
EMBO JOURNAL. 2025;44(17):4666-4680. doi: 10.1038/s44318-025-00482-5.

CHCHD4 Oxidoreductase Activity: A Comprehensive Analysis of the Molecular, Functional, and Structural Properties of Its Redox-Regulated Substrates.
Balasco N, Modjtahedi N, Monti A, Ruvo M, Vitagliano L, Doti N.
MOLECULES. 2025;30(10). doi: 10.3390/molecules30102117.

Core-Extended Naphthalene Diimide Dyads as Light-Up Probes with Targeted Cytotoxicity Toward Tumor Cells.
Pirota V, Salvati E, Risoldi C, Manoli F, Rizzo A, Zizza P, Biroccio A, Freccero M, Manet I, Doria F.
BIOMOLECULES. 2025;15(2). doi: 10.3390/biom15020311.

Core-shell polymeric micelles based on the 2-(hydroxyimino)aldehyde group as self-contained nanoreactors to obtain single and clustered ultra-small silver nanoparticles.
Masci G, D'Acunzo F, Casciardi S, Cirigliano A, Del Giudice A, Mura F, Passarini E, Schifano E, Pastore GM, Petrianni C, Gentili P.
EUROPEAN POLYMER JOURNAL. 2025;236(236):1141-1147. doi: 10.1016/j.eurpolymj.2025.114147.

Cxcr3 promotes protection from colorectal cancer liver metastasis by driving NK cell infiltration and plasticity.
Russo E, D'Aquino C, Di Censo C, Laffranchi M, Tomaipitinca L, Licursi V, Garofalo S, Promeuschel J, Peruzzi G, Sozio F, Kaffke A, Garlanda C, Panzer U, Limatola C, Vosshenrich CAJ, Sozzani S, Sciumè G, Santoni A, Bernardini G.
THE JOURNAL OF CLINICAL INVESTIGATION. 2025;135(11). doi: 10.1172/jci184036.

Determinants of Chain Selection and Staggering in Heterotrimeric Collagens: A Comprehensive Review of the Structural Data.
Vitagliano L, Doti N, Balasco N.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2025;26(20). doi: 10.3390/ijms262010134.

Development of New Chiral Amino Alcohol Ligand for the Asymmetric Transfer Hydrogenation of Ketones and Its Immobilization Onto Nanomaterials for an Ease of Recovery and Reuse.
Primitivo L, Deangelis M, Lucci G, Bonanni L, Suber L, Righi G, Ricelli A.
CHIRALITY. 2025;37(3):1-11. doi: 10.1002/chir.70031.

Discovery of First-in-Class Carbonic Anhydrase/Histone Deacetylase Dual Inhibitors with Antiproliferative Activity in Cancer Cells.
Bozdag M, Mroweh N, Raucci A, Angeli A, Peppicelli S, Biagioni A, Calorini L, Trisciuoglio D, Ragno R, Astolfi R, Giuliani L, Zwergel C, Valente S, Andreucci E, Carta F, Mai A, Supuran CT.
JOURNAL OF MEDICINAL CHEMISTRY. 2025;68(21):22874-22895. doi: 10.1021/acs.jmedchem.5c01788.

DNA damage response defects induced by the formation of TDP-43 and mutant FUS cytoplasmic inclusions and their pharmacological rescue.
Modafferi S, Farina S, Esposito F, Brandi O, Di Salvio M, Della Valle I, D'Uva S, Scarian E, Cicio G, Riccardi A, Pisati F, Garbelli A, Santini T, Pansarasa O, Morlando M, D'Ambrosi N, Cozzolino M, Cestra G, D'Adda Di Fagagna F, Gioia U, Francia S.
CELL DEATH AND DIFFERENTIATION. 2025;32(12):2309-2322. doi: 10.1038/s41418-025-01530-7.

DNPcall: a new pipeline for accurate double nucleotide polymorphism calling.
Pistacchia L, Ravasini F, Bella E, D'Atanasio E, Cruciani F, Trombetta B.
BIOINFORMATICS ADVANCES. 2025;5(1). doi: 10.1093/bioadv/vbaf209.

Droplet-Based Synthesis of Nanogels for Controlled Drug Delivery via Two Photon Polymerization-3D Printed Microfluidic Device.
Matining V, Colli C, Jacchetti E, Nicoletti G, Rosano L, Raimondi MT, Colosimo BM, Mauri E, Moscatelli D.
ADVANCED MATERIALS TECHNOLOGIES. 2025;10(19). doi: 10.1002/admt.202500108.

Editorial: Insights in theoretical modelling, structure prediction and design.
Ilari A, Morea V, Miele AE.
FRONTIERS IN CHEMICAL BIOLOGY. 2025;4. doi: 10.3389/fchbi.2025.1653901.

EGF receptor in organ development, tissue homeostasis and regeneration.
Tito C, Masciarelli S, Colotti G, Fazi F.
JOURNAL OF BIOMEDICAL SCIENCE. 2025;32(1). doi: 10.1186/s12929-025-01119-9.

Epigenetic regulation of TDP-43: potential implications for amyotrophic lateral sclerosis.
Mengistu DY, Terribili M, Pellacani C, Ciapponi L, Marzullo M.
FRONTIERS IN MOLECULAR MEDICINE. 2025;5(13). doi: 10.3389/fmmed.2025.1530719.

Estrogen rescues muscle regeneration impaired by DUX4 in a humanized xenograft mouse model.
Maiullari S, Mele G, Calandra P, Di Blasio G, Valentini S, Torcinaro A, Manni I, Teveroni E, Mancino F, Proietti L, Maiullari F, Pesavento M, Giorgini L, Putti S, Rizzi R, Bortolani S, Scavizzi F, Raspa M, Ricci E, Piaggio G, Gargioli C, Pontecorvi A, Luvisetto S, Mazzone M, Deidda G, Moretti F.
CELL DEATH & DISEASE. 2025;16(1). doi: 10.1038/s41419-025-07827-2.

Evaluating the effects of a multisectoral dialogue-based COVID-19 awareness-raising intervention in a limited-resource setting: A quasi-experimental study in Senegal.
Kislaya I, Caserta M, Faye SLB, Dia OK, Sow GHC, Doumbia CO, De Vito F, Bousso D, Strauss R, Ndiaye SAL, Diene HA, Calizza E, Sarr M, May J, Puradiredja DI, Inglessis M, Fusco D.
VACCINE. 2025;56. doi: 10.1016/j.vaccine.2025.127168.

Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis.
Exertier C, Antonelli L, Brufani V, Colotti G, Ilari A, Fiorillo A.
FRONTIERS IN CHEMICAL BIOLOGY. 2025;4. doi: 10.3389/fchbi.2025.1605579.

Fast, Comprehensive, and User Customizable Macromolecule Interface Analysis with FACE2FACE.
Di Micco P, Incarnato M, Pascarella G, Via A, Morea V.
JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2025;(18). doi: 10.1021/acs.jcim.5c00771.

GABAergic MicroRNA-34a in the Dorsal Raphe Nuclei Contributes to Circulating MicroRNA-34a Levels.
Guzzo SM, Ielpo D, Palazzo C, Nutarelli S, Fiori E, Tittarelli E, Cifani C, Pascucci T, Marchetti C, Viscomi MT, Andolina D, Lo Iacono L.
MOLECULAR NEUROBIOLOGY. 2025;63(1). doi: 10.1007/s12035-025-05575-0.

Gaseous ligand binding to Porphyromonas gingivalis HmuY hemophore-like protein in complex with heme.
Exertier C, Montemiglio LC, Tognaccini L, Zamparelli C, Vallone B, Olczak T, Śmiga M, Smulevich G, Malatesta F.
JOURNAL OF INORGANIC BIOCHEMISTRY. 2025;269. doi: 10.1016/j.jinorgbio.2025.112879.

Genome biology of long non-coding RNAs in humans: A virtual karyotype.
Palma A, Buonaiuto G, Ballarino M, Laneve P.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL. 2025;27:575-584. doi: 10.1016/j.csbj.2025.01.026.

Green synthesis and two-step chromatographic separation of thiocanthal and thiocanthol: Two novel biologically active sulfur derivatives of oleocanthal and oleacein from extra virgin olive oil.
Di Risola D, Mattioli R, Federico R, Pascarella G, Fontana M, Dainese E, Dufrusine B, Ciogli A, Gasparrini F, Morea V, Villani C, Mosca L, Francioso A.
FOOD CHEMISTRY. 2025;463(Pt 2). doi: 10.1016/j.foodchem.2024.141296.

Harmonization trial of FGFR1-3 testing strategies in cholangiocarcinoma patients: an Italian multicenter experience.
Pepe F, Russo G, Scimone C, Palumbo L, Tommasi S, Pinto R, De Biase D, Maloberti T, Busico A, Santoro A, Salemi D, Melucci E, Cozzolino D, Toffolatti L, Bessi S, Sarracino C, Tomaiuolo I, Minucci A, Roscigno G, Esposito F, Pallante P, Lonardi S, Pruneri G, Troncone G, Fassan M, Malapelle U.
PATHOLOGICA. 2025;117(5). doi: 10.32074/1591-951X-1317.

Harmonization trial on ESR1 testing strategies in ER+/HER2- breast cancer patients: an Italian experience.
Pepe F, Russo G, Venetis K, Scimone C, Palumbo L, Nacchio M, Di Giovanni D, Sarracino C, Tomaiuolo I, Zulato E, Fassan M, Righi D, Perrone G, De Biase D, Casati G, Pagni F, Gullotti L, Rizzo A, Perez A, Russo A, Zavaglia K, Gragnano G, Cozzolino D, Alfano S, Scatena C, D'Andrea S, Schiappacassi M, Roscigno G, Paganotti A, Boldorini R, Esposito F, Pallante P, Furlan D, Sbaraglia M, Dei Tos AP, Troncone G, Fusco N, Malapelle U.
THE JOURNAL OF LIQUID BIOPSY. 2025;9. doi: 10.1016/j.jlb.2025.100314.

IL-1β contributes to neurological disability in NMOSD AQP4 + Patients.
Bruno A, Borrelli A, Lauritano G, Di Lemme S, Di Caprio V, Fantozzi R, Dolcetti E, Azzolini F, Gilio L, Galifi G, Furlan R, Finardi A, De Vito F, Musella A, Mandolesi G, Bassi MS, Centonze D, Buttari F.
NEUROLOGICAL SCIENCES. 2025;46(12):6687-6695. doi: 10.1007/s10072-025-08526-8.

Interplay between ALK2R206H mutant receptor and autophagy signaling regulates receptor stability and its chondrogenic functions.
Coculo L, Wits M, Mariani I, Fianco G, Cappato S, Bocciardi R, Pedemonte N, Volpe E, Ciolfi S, Sessa RL, Rinaldo S, Cutruzzola F, Trisciuoglio D, Goumans MJ, Sanchez-Duffhues G, Stagni V.
CELL DEATH DISCOVERY. 2025;11(1). doi: 10.1038/s41420-025-02393-0.

Lipid deprivation amplifies type I IFN responses in monocytes through prenylation: insights from familial combined hypolipidemia type 2.
Pinzon Grimaldos A, Pacella I, Giacomelli T, Bini S, Di Costanzo A, Minicocci I, D'Erasmo L, Pietropaolo G, Licursi V, Arca M, Piconese S.
JOURNAL OF TRANSLATIONAL MEDICINE. 2025;24(1). doi: 10.1186/s12967-025-07448-5.

Live-cell imaging of circular and long noncoding RNAs associated with FUS pathological aggregates by Pepper fluorescent RNA.
Vitiello E, Castagnetti F, Mecarelli LS, D'Ambra E, Tollis P, Ruocco G, Laneve P, Caffarelli E, Mariani D, Bozzoni I.
RNA. 2025;31(4):529-548. doi: 10.1261/rna.080119.124.

LncRNA HSCHARME is altered in human cardiomyopathies and promotes stem cell-derived cardiomyogenesis via splicing regulation.
Buonaiuto G, Desideri F, Setti A, Palma A, D'Angelo A, Storari G, Santini T, Laneve P, Trisciuoglio D, Ballarino M.
NATURE COMMUNICATIONS. 2025;16(1). doi: 10.1038/s41467-025-62754-2.

Microglia depletion in a mouse model of prenatal and postnatal immune activation.
Ciano Albanese N, Del Castillo I, Ragaglia G, Castellano G, Ajmone-Cat MA, De Simone R, Griguoli M, Ricceri L.
Brain, Behavior and Immunity. 2025.

Modulating TERRA G-quadruplexes with ligands: impact on telomeric DNA:RNA hybrids and ALT mechanisms.
Dinoi F, Marzano S, Marino MI, Vertecchi E, D'Angelo CM, Maresca C, Petti E, Dinami R, Rizzo A, Biroccio A, Cacchione S, Pagano B, Salvati E, Amato J.
NUCLEIC ACIDS RESEARCH. 2025;53(22). doi: 10.1093/nar/gkaf1300.

Molecular Insights into IAHSP: Influence of the R1611W Mutation on the VPS9 Domain of Alsin.
Miceli M, Exertier C, Gugole E, Vallone B, Agostino Deriu M.
ACS OMEGA. 2025;10(45):54138-54147. doi: 10.1021/acsomega.5c05926.

Mutational analysis of the Drosophila CMG helicase reveals relationships among chromosome integrity and the maintenance of spindle and centrosome structure.
Graziadio L, Scatolini L, Bucciarelli E, Raffa GD, Bonaccorsi S, Gatti M.
GENETICS. 2025;231(1). doi: 10.1093/genetics/iyaf124.

NF-κB-mediated cytokine secretion and glutamate metabolic reprogramming converge in breast cancer brain tropism.
Di Russo S, Borsatti GE, Bouzidi A, Liberati FR, Riva A, Tripodi F, Rolfi LR, Spizzichino S, Tramutola A, Perluigi M, Trisciuoglio D, Giardina G, Paiardini A, Coccetti P, Rinaldo S, Cutruzzolà F, Paone A.
CANCER LETTERS. 2025;630. doi: 10.1016/j.canlet.2025.217907.

Novel Humanized Anti-HER3 Antibodies: Structural Characterization and Therapeutic Activity.
Muzi A, Arriga R, Bulfaro G, Fata F, Costanzo A, Chiarini V, Cappelletti M, Fosca Ferrara F, Bucci F, Montemiglio LC, Savino C, Marra E, Ciliberto G, Aurisicchio L, Vallone B, Roscilli G.
ANTIBODIES. 2025;14(4). doi: 10.3390/antib14040084.

NSD2 and miRNAs as Key Regulators of Melanoma Response to Romidepsin and Interferon‐α2b Treatment.
De Santis A, De Santis L, Rossi F, Gasparini S, Licursi V, Amico VA, Capone I, Fragale A, D'Atri S, Gabriele L, Presutti C.
CANCER MEDICINE. 2025;14(10). doi: 10.1002/cam4.70917.

Optical signature of retinal Tau fibrillation.
Salajková Z, Barolo L, Baiocco P, Ruzicka B, Mura F, Di Lorenzo F, Boffi A, Ricco V, Ruocco G, Leonetti M.
SCIENTIFIC REPORTS. 2025;15(1). doi: 10.1038/s41598-025-92565-w.

Out of the Niche: A Bird’s-Eye View of the Molecular Networks Controlling Root Stem Cells.
Sessa G, Morelli G, Sassi M.
PLANTS. 2025;14(16). doi: 10.3390/plants14162574.

PACS deficiency disrupts Golgi architecture and causes cytokinesis failures and seizure-like phenotype in Drosophila melanogaster.
Frappaolo A, Zaccagnini G, Riparbelli M, Colotti G, Callaini G, Giansanti M.
OPEN BIOLOGY. 2025;15(2). doi: 10.1098/rsob.240267.

Peptide-mimetics derived from leucyl-tRNA synthetase are potential agents for the therapy of mt-tRNA related diseases.
Pisano A, Belloli S, Pignataro MG, Rainone P, Valtorta S, Coliva A, De Turris V, Mosca L, Di Micco P, Moresco RM, D'Amati G, Morea V.
FRONTIERS IN PHARMACOLOGY. 2025;16. doi: 10.3389/fphar.2025.1607343.

Phytoremediation of perfluoroalkyl and polyfluoroalkyl substances (PFAS): Insights on plant uptake, omics analysis, contaminant detection and biomass disposal.
Marzi D, Valente F, Luche S, Caissutti C, Sabia A, Capitani I, Capobianco G, Serranti S, Masi A, Panozzo A, Ricci A, Bolla PK, Vamerali T, Brunetti P, Visioli G.
SCIENCE OF THE TOTAL ENVIRONMENT. 2025;959. doi: 10.1016/j.scitotenv.2024.178323.

Primary Auxin Response Genes GH3s and DAO1 Modulate Stamen Elongation in Arabidopsis thaliana and Solanum lycopersicum.
Marzi D, Antenozio ML, Ghelli R, Cecchetti V, Iacobini FR, Beccaccioli M, Reverberi M, Picarella ME, Mazzucato A, Brunetti P, Cardarelli M.
PHYSIOLOGIA PLANTARUM. 2025;177(3). doi: 10.1111/ppl.70340.

Quinoline-Based DNA Methyltransferase Inhibitors Featuring Basic Side Chains: Design, Synthesis, and Insight in Biochemical and Anticancer Cell Properties.
Zwergel C, Lambona C, Fioravanti R, Raucci A, Fiorentino F, Nchugoua Tchieh G, Jallet C, Lacroix L, Pierrettori M, Pellegrini FR, Xiong Y, Jin J, Arimondo P, Trisciuoglio D, Mai A, Valente S.
JOURNAL OF MEDICINAL CHEMISTRY. 2025;68(22):23886-23909. doi: 10.1021/acs.jmedchem.5c01029.

Rare uniparental lineages reveal external ancestries in the gene pool of the Italian linguistic enclave of Grecìa Salentina.
Menato F, Pepe G, Mercuri E, Zangaro F, Cangialosi G, Jodice C, Gulì M, Cruciani F, Trombetta B, Helmer-Citterich M, D'Atanasio E, Guardiano C, Longobardi G, Semino O, Novelletto A, Specchia V.
SCIENTIFIC REPORTS. 2025. doi: 10.1038/s41598-025-31756-x.

RNA-mediated inhibition of mitochondrial SHMT2 impairs cancer cell proliferation.
Liberati FR, Spizzichino S, Di Russo S, Borsatti GE, Riva A, Magnifico MC, Bouzidi A, Giardina G, Arese M, Scribani Rossi C, Boi D, Boumis G, Di Fonzo F, Guarguaglini G, Contestabile R, Tramonti A, Macone A, Paiardini A, Rinaldo S, Paone A, Cutruzzolà F.
CELL DEATH DISCOVERY. 2025;11(1). doi: 10.1038/s41420-025-02646-y.

Selection of short Gadd45β-binding peptides through a synergistic computational and biophysical approach.
Di Cristofano S, Iaccarino E, Caporale A, Verzella D, Falcigno L, D'Auria G, Russo R, Rega C, Chambery A, Oliver A, Barisciano G, Cross S, Cruciani G, Capece D, Zazzeroni F, Ruvo M, Sandomenico A, Raimondo D.
PROTEIN SCIENCE. 2025;34(12). doi: 10.1002/pro.70380.

Semaphorin 5A modulates focal adhesion pathway and lamellipodia formation in melanoma.
Brignone M, Cufaro MC, Ercolani C, Masi I, Di Ferdinando F, Palange A, Valentini E, Di Martile M, Del Boccio P, Del Bufalo D, Tamagnone L, Rosanò L, D'Aguanno S.
CELL COMMUNICATION AND SIGNALING. 2025;23(1). doi: 10.1186/s12964-025-02526-z.

SERTM2: a neuroactive player in the world of micropeptides.
Lisi M, Santini T, D'Andrea T, Salvatori B, Setti A, Paiardini A, Nutarelli S, Nicoletti C, Pellegrini F, Fucile S, Bozzoni I, Martone J.
EMBO REPORTS. 2025;26(8):2044-2076. doi: 10.1038/s44319-025-00404-w.

Sex-Related Differences in Physiological and Biochemical Responses of Populus nigra to Bifunctionalized Silver Nanoparticles and Silver Ions Exposure In Vitro.
Iori V, Gentile D, Casentini B, Camoni L, Fiorillo A, Kuzminsky E, Venditti I, Iannelli MA.
PLANTS. 2025;14(23). doi: 10.3390/plants14233560.

Sorcin regulates alveolarization and airway tissue remodeling during lung morphogenesis.
Tito C, De Angelis L, Iaiza A, Abbinantefina AP, Benedetti A, Mazzanti G, Petrozza V, Lauriola M, Tamagnone L, Ilari A, Masciarelli S, Colotti G, Fazi F.
CELLULAR AND MOLECULAR LIFE SCIENCES. 2025;82(1). doi: 10.1007/s00018-025-05870-y.

Specialty grand challenges in theoretical modeling, structure prediction and design.
Exertier C, Ilari A.
FRONTIERS IN CHEMICAL BIOLOGY. 2025;4. doi: 10.3389/fchbi.2025.1635423.

Structural and functional characterization of self-assembling fragments identified from the transthyretin amyloid-like structure.
Pizzella M, Accardo A, Mercurio FA, Sibillano T, Gallo E, Morelli G, Smaldone G, Giannini C, Leone M, Balasco N, Diaferia C, Vitagliano L.
NANOSCALE. 2025;17(38):22436-22455. doi: 10.1039/d5nr02939b.

Structural Biology in the AlphaFold Era: How Far Is Artificial Intelligence from Deciphering the Protein Folding Code?.
Balasco N, Esposito L, Vitagliano L.
BIOMOLECULES. 2025;15(5). doi: 10.3390/biom15050674.

Structure and function of persulfide dioxygenase from Pseudomonas aeruginosa: Implications on H2S homeostasis and interplay with nitric oxide.
Giordano F, Troilo F, Roberta Nastasi M, Caruso L, Mellini M, Travaglini-Allocatelli C, Giardina G, B Vicente J, Rampioni G, Di Matteo A, Forte E, Giuffrè A.
ISCIENCE. 2025.

Targeting MDM2 affects spastin protein levels and functions: implications for HSP treatment.
Sardina F, Polverino F, Valentini S, Carsetti C, Falvo E, Tisci G, Soddu S, Moretti F, Paiardini A, Rinaldo C.
CELL DEATH DISCOVERY. 2025;(1).

Targeting the MDM2-MDM4 interaction interface reveals an otherwise therapeutically active wild-type p53 in colorectal cancer.
Valentini S, Mele G, Attili M, Assenza MR, Saccoccia F, Sardina F, Rinaldo C, Massari R, Tirelli N, Pontecorvi A, Moretti F.
MOLECULAR ONCOLOGY. 2025;19(8):2412-2430. doi: 10.1002/1878-0261.70006.

The dual-site agonist for human M2 muscarinic receptors Iper-8-naphtalimide induces mitochondrial dysfunction in Saccharomyces cerevisiae.
Cirigliano A, Amelina A, Passarini E, Ricelli A, Balasco N, Mori M, Botta B, De Stefano ME, Papotto C, Guerriero C, Tata AM, Rinaldi T.
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The Dynamics of the ESCRT Machinery in Open Mitosis from Physiology to Pathology.
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CELLS. 2025;14(21). doi: 10.3390/cells14211681.

The extracellular matrix protein type I collagen and fibronectin are regulated by β-arrestin-1/endothelin axis in human ovarian fibroblasts.
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The GLP-1R agonist semaglutide reshapes pancreatic cancer associated fibroblasts reducing collagen proline hydroxylation and favoring T lymphocyte infiltration.
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The HD-ZIP II Transcription Factors HAT3 and ATHB4 Fine-Tune Auxin and Cytokinin Pathways During Flower Development.
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PLANTS. 2025;14(24). doi: 10.3390/plants14243723.

The MYC-dependent lncRNA MB3 inhibits apoptosis in Group 3 Medulloblastoma by regulating the TGF-β pathway via HMGN5.
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The origin of modern North Africans as depicted by a massive survey of mitogenomes.
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The “Bagno dell’Acqua” Lake as a Novel Mars-like Analogue: Prebiotic Syntheses of PNA and RNA Building Blocks and Oligomers.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2025;26(14). doi: 10.3390/ijms26146952.

TNF Production or TNFR2 Expression Characterize Distinct States of Regulatory T Cells that Cooperate in Treg Expansion in Cancer and Chronic Inflammation.
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EUROPEAN JOURNAL OF IMMUNOLOGY. 2025;55(9). doi: 10.1002/eji.70062.

TRF2 interaction with nuclear envelope is required for cell polarization and metastasis in triple negative breast cancer.
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Unraveling the Engagement of Kinases to CRBN Through a Shared Structural Motif to Optimize PROTACs Efficacy.
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BIOMOLECULES. 2025;15(2). doi: 10.3390/biom15020206.

Uptake and Effects of Microplastics in Pteris Vittata Plants Grown on Soil Amended with Sewage Sludge.
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JOURNAL OF ENVIRONMENTAL MANAGEMENT. 2025. doi: 10.2139/ssrn.4950745.

Urban Health Assessment Through a Planetary Health Perspective: Methods and First Results from the Rome NBFC Experiment.
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ATMOSPHERE. 2025;16(10):1144-1144. doi: 10.3390/atmos16101144.

Urbanization and genetic homogenization in the medieval Low Countries revealed through a ten-century paleogenomic study of the city of Sint-Truiden.
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Vitamin B6 deficiency produces metabolic alterations in Drosophila.
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METABOLOMICS. 2025;21(2). doi: 10.1007/s11306-025-02236-0.

Yeast Oral Delivery of DAF16 shRNAs Results in Effective Gene Silencing in C. elegans.
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CURRENT ISSUES IN MOLECULAR BIOLOGY. 2025;47(7). doi: 10.3390/cimb47070570.