• Istituto di Biologia e Patologia Molecolari

Tel :0649913401 (studio); 0649913617 (lab.)
Fax :0649913628
Senior Researcher

Istitute of Molecular Biology and Pathology - National Research Council
Department of Chemistry
Sapienza University of Rome - Edificio di Chimica, edificio Cannizzaro (VEC) Piano terzo, stanza 320 (lab: 319) P.le A. Moro 5 - 00185 Roma
 -Isolation and identification of new glycosidic iridoids
- Preparation of 1,3-diols and their use in the synthesis of natural products
-Study of methods for the regio-and stereocontrolled opening of three-membered heterocycles ring 2-functionalized and applications to the synthesis of biologically active compounds
- Synthesis of new calix [4] arenes functionalized at the upper rim with aminoalcoholic sequences
- Synthesis of new peptidomimetics as potential inhibitors of HIV-protease
- Development of a new approach to the synthesis of iminosugars and preparation of new glycosidase inhibitors  
-Synthesis of functional magnetic nanoparticles for catalytic applications
-Synthesis of new inhibitors of Bcl-2 analogs of Obatoclax
-Synthesis of new polyphenols with flavonoid and stilbenoide structure
Barontini, M.; ProiettiSilvestri, I.; Nardi, V.; Crisante, F.; Pepe, G.; Pari, L.; Gallucci, F.; Bovicelli, P.; Righi, G. “Synthesis and biological evaluation of gallic acid analogs” Medicinal Chemistry Research 2013, 22(2), 674-680.
Lombardo, E.; Sabellico, C.; Hajek, J.; Stankova, V.; Filipsky, T.; Balducci, V.; De Vito, P.; Leone, S.; Bavavea, E. I.; ProiettiSilvestri, I.; Righi, G.; Luly, P.; Saso, L.; Bovicelli, P.; Pedersen, J. Z.; Incerpi, S. “Protection of Cells against Oxidative Stress by Nanomolar Levels of Hydroxyflavones Indicates a New Type of Intracellular Antioxidant Mechanism” Plos One 2013, 8(4), e60796
Barontini, M.; Proietti Silvestri, I.; Nardi, V.; Bovicelli, P.; Pari, L.; Gallucci, F.; Spezia, R.; Righi, G. “Easy eco-friendlyphenoniumion production from phenethylalcohols in dimethyl carbonate” Tetrahedron Letters 2013, 54(37), 5004-5006. 
Righi, Giuliana; Bovicelli, Paolo; Ilaria Tirotta”New one-pot procedure for the synthesis of diprotected amino alcohols from unprotected vinyl aziridines” Tetrahedron Lett. 2013, 54, 6439-6442.
Righi, Giuliana; Scotti, Giorgio; Caruso, Francesco; Rossi, Miriam; Mecozzi, Francesco; Antonioletti, Roberto; Pelagalli, Romina “Lewis acid-mediated azidolysis of 2,3-three membered heterocyclic amines” Tetrahedron  2013, 69, 9557-9563.
Righi, Giuliana; Antonioletti, Roberto; Pelagalli, Romina “A highly regioselective azidolysis of 2,3-epoxy amines: an unexpected [Ti(O-i-Pr)2(N3)2] mediated C-2 opening” Tetrahedron Lett. 2012, 53, 5582-5585.  
 Righi, Giuliana; Bovicelli, Paolo; Mandic’, Emanuela; Naponiello, Gaia Clara Mercedes; Ilaria Tirotta”Study on the stereochemical control of dihydroxylation of vinyl epoxides and their derivatives” Tetrahedron 2012, 68, 2984-2986.
Righi, Giuliana; Bovicelli, Paolo; Marucci, Cristina; Ilaria Tirotta “BF3•Et2O/TMSN3 mediated regioselective azidolysis of vinyl aziridines” Synthesis 2012, 44, 3202-3208
Righi, Giuliana;  Mantineo, Agnese;  Suber, Lorenza;  Mari,  Alessandra “Ti(O-iPr)4 promoted regio- and stereoselective aminolysis of 2,3-epoxy amides” Synlett 2012, 23, 1947-1949.
Righi, Giuliana; Bovicelli, Paolo; Barontini, Maurizio; Tirotta, Ilaria”Dimethyl carbonate in the regio- and stereocontrolled opening of three-membered heterocyclic rings” Green Chemistry 2012, 2, 495-502.
Dr. Paolo Bovicelli
Dr.ssa Giuliana Righi
Dr.ssa Alessandra Ricelli
Dr. Roberto Antonioletti
Work experience
CNR Matric. N.  18175
Qual.   Researcher, Level II 

After the degree in Chemistry (1981, Rome, University "La Sapienza") she has been working for the CNR since 1984 at the Institute of Biomolecular Chemistry (ex Center for the Study of the Chemistry of Natural Organic Compounds) first as Researcher and, since 31/12/2001, as First Researcher II level.
In 2001 and 2002 she was responsible of the research “Epoxides and aziridine in the synthesis of biologically active substances" and from 2004 she is responsible of Mod. PM.P01.010.003); she has also worked at various National Projects: COFIN 2002, FIRB 2001, PRIN 2003, PRIN 2005 and PRIN 2008.
She participated at numerous congresses and conferences, at the IASOC III, IV and V (Ischia Advanced School of Organic Chemistry) and at the Summer School "A. Corbella "Organic Synthesis (IX, X and XI). At this school, in June 1999 she was invited to give a lecture.
She is the author of one Italian patent, 76 scientific publications on international journals (among them two chapter respectively on Recent Research Development in Organic Chemistry and Target in Heterocyclic Systems and two reviews respectively on Synthesis and Tetrahedron) and numerous communications at meeting.                
She is Tutor of numerous experimental theses for degrees in Chemistry and for PhDs in Chemical Sciences. 
She was responsible of research programs related to three scholarships for CNR (call n.201.03.17 of 21/05/1988; call No. 201.03.20 of 13/07/1992; call n.201.03.29 of 05/06/2000). 
In 1994 was appointed a member of the Scientific Board of the Center for the Study of the Chemistry of Natural Organic Compounds. 
In September 2001 she was called upon to be part to the board of examiner for the No. 1 position of Technician (call No 310.2.104/M-Cod. CT54 / 1) at the Institute for the Study of Natural Substances of Food and Chemical-Pharmaceutical Interest (Valverde-CT).
She is referee of international journal such as Synlett, Tetrahedron: Asymmetry and Journal of Organic Chemistry.