• Istituto di Biologia e Patologia Molecolari

Pubblicazioni 2022

Patrizia Lavia, Ilaria Sciamanna and Corrado Spadafora.
An Epigenetic LINE-1-Based Mechanism in Cancer.
International journal of molecular sciences (Online)

Roberto Mattioli (a,1), Gianmarco Pascarella (b,1), Riccardo D'Incà (a), Alessandra Cona (a,d), Riccardo Angelini (a,d), Veronica Morea (c,**), Paraskevi Tavladoraki (a,d,*).
Arabidopsis N-acetyltransferase activity 2 preferentially acetylates 1,3-diaminopropane and thialysine.
Plant physiology and biochemistry (Paris): 123-132

Nogués, Isabel; Sekula, Bartosz; Angelaccio, Sebastiana; Grzechowiak, Marta; Tramonti, Angela; Contestabile, Roberto; Ruszkowski, Milosz.
Arabidopsis thaliana serine hydroxymethyltransferases: functions, structures, and perspectives.
Plant physiology and biochemistry (Paris): 37-49

Tramonti A, Ghatge MS, Babor JT, Musayev FN, di Salvo ML, Barile A, Colotti G, Giorgi A, Paredes SD, Donkor AK, Al Mughram MH, de Crécy-Lagard V, Safo MK, Contestabile R.
Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): role of lysine residues in PLP binding and protein stability.
Protein science (Online)

Manganaro L.; Celli V.; Viggiani V.; Berardelli E.; Granato T.; Tartaglione S.; Farina A.; Catalano C.; Angeloni A.; Anastasi E.
CT imaging phenotypes linked to CA125 and HE4 biomarkers are highly predictive in discriminating between hereditary and sporadic ovarian cancer patients.
Tumor biology (Online): 171-185

Boyko AI, Karlina IS, Zavileyskiy LG, Aleshin VA, Artiukhov AV, Kaehne T, Ksenofontov AL, Ryabov SI, Graf AV, Tramonti A, Bunik VI.
Delayed Impact of 2-Oxoadipate Dehydrogenase Inhibition on the Rat Brain Metabolism Is Linked to Protein Glutarylation.
Frontiers in medicine

Balashova NV, Zavileyskiy LG, Artiukhov AV, Shaposhnikov LA, Sidorova OP, Tishkov VI, Tramonti A, Pometun AA, Bunik VI.
Efficient Assay and Marker Significance of NAD+ in Human Blood.
Frontiers in medicine

Di Risola D.; Ricci D.; Marrocco I.; Giamogante F.; Grieco M.; Francioso A.; Vasco-Vidal A.; Mancini P.; Colotti G.; Mosca L.; Altieri F.
ERp57 chaperon protein protects neuronal cells from A?-induced toxicity.
Journal of neurochemistry: 322-336

Gabanella F.; Barbato C.; Corbi N.; Fiore M.; Petrella C.; de Vincentiis M.; Greco A.; Ferraguti G.; Corsi A.; Ralli M.; Pecorella I.; Di Gioia C.; Pecorini F.; Brunelli R.; Passananti C.; Minni A.; Di Certo M.G.
Exploring Mitochondrial Localization of SARS-CoV-2 RNA by Padlock Assay: A Pilot Study in Human Placenta.
International journal of molecular sciences (Print)

Fiorillo A.; Colotti G.; Exertier C.; Liuzzi A.; Seghetti F.; Salerno A.; Caciolla J.; Ilari A.
Innovative Approach for a Classic Target: Fragment Screening on Trypanothione Reductase Reveals New Opportunities for Drug Design.
Frontiers in Molecular Biosciences

Giansanti M.G.; Piergentili R.
Linking GOLPH3 and Extracellular Vesicles Content-a Potential New Route in Cancer Physiopathology and a Promising Therapeutic Target is in Sight?.
Technology in cancer research and treatment (Online): 1-7

Frappaolo, Anna; Piergentili, Roberto; Giansanti, Maria Grazia.
Microtubule and Actin Cytoskeletal Dynamics in Male Meiotic Cells of Drosophila melanogaster.
Cells

Sechi, Stefano; Piergentili, Roberto; Giansanti, Maria Grazia.
Minor Kinases with Major Roles in Cytokinesis Regulation.
Cells

Morotti, Marta; Garofalo, Stefano; Cocozza, Germana; Antonangeli, Fabrizio; Bianconi, Valeria; Mozzetta, Chiara; De Stefano, Maria Egle; Capitani, Riccardo; Wulff, Heike; Limatola, Cristina; Catalano, Myriam; Grassi, Francesca.
Muscle Damage in Dystrophic mdx Mice Is Influenced by the Activity of Ca<sup>2+</sup>-Activated K<inf>Ca</inf> 3.1 Channels.
Life (Basel)

Damizia M Altieri L Lavia P.
Non-transport roles of nuclear import receptors: In need of the right balance.
Frontiers in Cell and Developmental Biology

Battista T.; Federico S.; Brogi S.; Pozzetti L.; Khan T.; Butini S.; Ramunno A.; Fiorentino E.; Orsini S.; Di Muccio T.; Fiorillo A.; Exertier C.; Di Risola D.; Colotti G.; Gemma S.; Ilari A.; Campiani G.
Optimization of Potent and Specific Trypanothione Reductase Inhibitors: A Structure-Based Drug Discovery Approach.
ACS Infectious Diseases: 1687-1699

Rossana Scrivo 1 , Emanuela Anastasi 2 , Chiara Castellani 3 , Fabrizio Conti 3 , Antonio Angeloni 2 , Teresa Granato 4.
Ovarian reserve in patients with spondyloarthritis: impact of biological disease-modifying anti-rheumatic drugs on fertility status.
Clinical and Experimental Rheumatology (Online)

Montemiglio L.C.; Gugole E.; Freda I.; Exertier C.; D'auria L.; Chen C.G.; Nardi A.N.; Cerutti G.; Parisi G.; D'abramo M.; Savino C.; Vallone B.
Point mutations at a key site alter the cytochrome P450 oleP structural dynamics.
Biomolecules

Veronica De Luca, Manuela Leo, Elisabetta Cretella, Arianna Montanari, Michele Saliola, Gabriele Ciaffi, Andrea Vecchione, Antonella Stoppacciaro* and Patrizia Filetici*.
Role of yUbp8 in Mitochondria and Hypoxia Entangles the 2 Finding of Human Ortholog Usp22 in the Glioblastoma 3 Pseudo-Palisade Microlayer.
Cells

Chen, Lu and Roake, Caitlin M and Maccallini, Paolo and Bavasso, Francesca and Dehghannasiri, Roozbeh and Santonicola, Pamela and Mendoza-Ferreira, Natalia and Scatolini, Livia and Rizzuti, Ludovico and Esposito, Alessandro and Gallotta, Ivan and Francia, Sofia and Cacchione, Stefano and Galati, Alessandra and Palumbo, Valeria and Kobin, Marie A and Tartaglia, Gian Gaetano and Colantoni, Alessio and Proietti, Gabriele and Wu, Yunming and Hammerschmidt, Matthias and De Pittà, Cristiano and Sales, Gabriele and Salzman, Julia and Pellizzoni, Livio and Wirth, Brunhilde and Di Schiavi, Elia and Gatti, Maurizio and Artandi, Steven E and Raffa, Grazia D.
TGS1 impacts snRNA 3'-end processing, ameliorates survival motor neuron-dependent neurological phenotypes in vivo and prevents neurodegeneration.
Nucleic acids research

Trisciuoglio, Daniela; Degrassi, Francesca.
The Tubulin Code and Tubulin-Modifying Enzymes in Autophagy and Cancer.
Cancers (Basel)

Bunik, Victoria; Aleshin, Vasily; Nogues, Isabel; Kähne, Thilo; Parroni, Alessia; Contestabile, Roberto; Salvo, Martino Luigi; Graf, Anastasia; Tramonti, Angela.
Thiamine-dependent regulation of mammalian brain pyridoxal kinase in vitro and in vivo.
Journal of neurochemistry

Leo, Manuela; Lattuada, Enrico; Caprara, Debora; Salvatori, Luisa; Vecchione, Andrea; Sciortino, Francesco; Filetici, Patrizia; Stoppacciaro, Antonella.
Treatment of kidney clear cell carcinoma, lung adenocarcinoma and glioblastoma cell lines with hydrogels made of DNA nanostars.
Biomaterials science (Print): 1304-1316

Mascolo E, Liguori F, Merigliano C, Schiano L, Gnocchini E, Pilesi E, Volonté C, Di Salvo ML, Contestabile R, Tramonti A, Vernì F.
Vitamin B6 rescues insulin resistance and glucose-induced DNA damage caused by reduced activity of Drosophila PI3K.
Journal of cellular physiology (Online)

Tiberti, Silvia; Catozzi, Carlotta; Croci, Ottavio; Ballerini, Mattia; Cagnina, Danilo; Soriani, Chiara; Scirgolea, Caterina; Gong, Zheng; He, Jiatai; Macandog, Angeli D.; Nabinejad, Amir; Lauson, Carina B. Nava; Quinte, Arianna; Bertalot, Giovanni; Petz, Wanda L.; Ravenda, Simona P.; Licursi, Valerio; Paci, Paola; Rasponi, Marco; Rotta, Luca; Fazio, Nicola; Ren, Guangwen; Fumagalli-Romario, Uberto; Schaefer, Martin H.; Campaner, Stefano; Lugli, Enrico; Nezi, Luigi; Manzo, Teresa.
GZMK(high) CD8(+) T effector memory cells are associated with CD15(high) neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome.
Nature communications

Wang, Wei; Di Nisio, Elena; Licursi, Valerio; Cacci, Emanuele; Lupo, Giuseppe; Kokaia, Zaal; Galanti, Sergio; Degan, Paolo; D'Angelo, Sara; Castagnola, Patrizio; Tavella, Sara; Negri, Rodolfo.
Simulated Microgravity Modulates Focal Adhesion Gene Expression in Human Neural Stem Progenitor Cells.
Life (Basel)