• Istituto di Biologia e Patologia Molecolari

Pubblicazioni 2006

Denti M.A., Rosa A., D'Antona G., Sthandier O., De Angelis F.G., Nicoletti C., Allocca M., Pansarasa O., Parente V., Musarò A., Auricchio A., Bottinelli R. and Bozzoni I.  
I  Body-wide gene therapy of Duchenne Muscular Dystrophy in the mdx mouse model.
Proceedings of the National Academy of Sciences of the United States of America;103: 3758-3763

Franceschini S, Ceci P, Alaleona F, Chiancone E, Ilari A.  
The antioxidant Dps protein from the thermophilic cyanobacterium Thermosynechococcus elongatus: an intrinsically stable cage-like structure endowed with enhanced stability.
The FEBS journal (Print);273: 4913-4928

Colotti, G.; Zamparelli, C.; Verzili D.; Mella M.; Loughrey C. M.; Smith G. L.; Chiancone. E.
The W105G and W99G sorcin mutants demonstrate the role of the D helix in the Ca2+-dependent interaction with annexin VII and the cardiac ryanodine receptor.
Biochemistry (Easton);45: 12519-12529

Ilari A ., Kjelgaard P., von Wachenfeldt C., Catacchio B., Chiancone E., Boffi A.
Crystal structure and ligand binding properties of the truncated hemoglobin from Geobacillus stearothermophilus .
Archives of biochemistry and biophysics (Print);457: 85-94

Bonamore A .; Macone A.; Colotti G.; Matarese R.M.; Boffi A.
The desaturase from Bacillus subtilis a promising tool for the selective olefination of phospholipids.
Journal of biotechnology;121: 49-53

Vicente J.B., Scandurra F.M., Rodrigues J.V., Brunori M., Sarti P., Teixeira M., Giuffrè A.
Kinetics of electron transfer from NADH to the Escherichia coli nitric oxide reductase flavorubredoxin.

Borisov VB; Forte E; Sarti P; Brunori; Konstantinov AA; Giuffrè A.
Nitric oxide reacts with the ferryl-oxo catalytic intermediate of the CuB-lacking cytochrome bd terminal oxidase.
FEBS letters (Print);580: 4823-4826

Brunori M; Forte E; Arese M; Mastronicola D; Giuffrè A; Sarti P.
Nitric oxide and the respiratory enzyme.
Biochimica et biophysica acta. Bioenergetics;1757: 1144-1154

Gianni S., Geierhaas C.D., Calosci N., Jemth P., Vuister G.W., Travaglini-Allocatelli C., Vendruscolo M, Brunori M.
A PDZ domain recapitulates a unifying mechanism for protein folding.
Proceedings of the National Academy of Sciences of the United States of America

Chi C .N., Engstrom A., Gianni S., Larsson M., Jemth P.
Two conserved residues govern the salt and pH dependencies of the binding reaction of a PDZ domain.
The Journal of biological chemistry (Print);281: 36811-36818

Gianni S., Walma T., Arcovito A., Calosci N., Bellelli A., Engstrom A., Travaglini-Allocatelli C., Brunori M., Jemth P., Vuister G.W.
Demonstration of long-range interactions in a PDZ domain by NMR, kinetics, and protein engineering.
Structure (Lond.);14: 1801-1809

Centola F ., Rinaldo S., Brunori M., Cutruzzolà F.
Critical role of His369 in the reactivity of Pseudomonas aeruginosa cytochrome cd1 nitrite reductase with oxygen.

Rinaldo S., Giardina G.,. Brunori M, Cutruzzolà F.
N-oxide sensing and denitrification: the DNR transcription factors.
Biochemical Society transactions;281: 9331-9336

Borgia A ., Bonivento D., Travaglini-Allocatelli C., Di Matteo A., Brunori M.
Unveiling a hidden folding intermediate in c-type cytochromes by protein engineering.

Tramonti A .; De Canio M.; Delany I.; Scarlato V.:De Biase D.
Mechanisms of transcription activation exerted by GadX and GadW at the gadA and gadBC gene promoters of the glutamate-based acid resistance system in Escherichia coli .
Journal of bacteriology (Print);188: 8118-8127

Giacometti A ., Cirioni O., Ghiselli R., Mocchegiani F., Orlando F., Silvestri C., Bozzi A., Di Giulio A., Luzi C., Mangoni M.L., Barra D., Saba V., Scalise G., Rinaldi A.C..
Interaction of antimicrobial peptide temporin L with lipopolysaccharide in vitro and in experimental rat models of septic shock caused by gram-negative bacteria.
Antimicrobial agents and chemotherapy (Print);50: 2478-2786

Mohamed  W., Darji  A., Domann E., Chiancone E., Chakraborty T.
The ferritin-like protein Frm is a target for the humoral response of Listeria monocytogenes and is required for efficient bacterial survival.
Molecular genetics and genomics (Print);275: 344-353

Mangoni M .L., Papo N., Saugar J.M., Barra D., Shai Y., Simmaco M., Rivas L..
Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H.
Biochemistry (Easton);45: 4266-4276

Renzi F; Caffarelli E; Laneve P; Bozzoni I; Brunori M; Vallone B.
The structure of the endoribonuclease XendoU: From small nucleolar RNA processing to severe acute respiratory syndrome coronavirus replication.
Proceedings of the National Academy of Sciences of the United States of America;103: 12365-12370

Eleonora Agricola,1+; Loredana Verdone,2+; Ernesto Di Mauro1,2; and Micaela Caserta2*.  
H4 acetylation does not replace H3 acetylation in chromatin remodelling and transcription activation of Adr1-dependent genes.
Molecular microbiology (Print);62: 1433-1446

Verdone L , Agricola E, Caserta M , Di Mauro E .
Histone acetylation in gene regulation.
Proteomics (Weinh., Print);5: 209-221

Xella B, Goding C, Agricola E, Di Mauro E , Caserta M .
The ISWI and CHD1 chromatin remodelling activities influence ADH2 expression and chromatin organization.
Molecular microbiology (Print);59: 1531-1541

Saladino R., Crestini  C., Ciciriello F., Costanzo G., Di Mauro E.
About a formamide-based origin of informational polymers: syntheses of nucleobases and favourable thermodynamic niches for early polymers.
Origins of life and evolution of the biosphere

Saladino R., Crestini C., Neri V., Ciciriello F., Costanzo G., Di Mauro E.
Origin of informational polymers: the concurrent roles of formamide and phosphates.
ChemBioChem (Print);7: 1707-1714

Saladino R., Crestini C., Ciciriello F., Di Mauro E., Costanzo G.
Origin of Informational Polymers: Differential Stability of Phosphoester Bonds in Ribo Monomers and Oligomers.

Galati A, Rossetti L, Pisano S, Chapman L, Rhodes D, Savino M , Cacchione S.
The human telomeric protein TRF1 specifically recognizes nucleosomal binding sites and alters nucleosome structure.
Journal of Molecular Biology;360: 377-385

Pisano S, Pascucci E, Cacchione S, De Santis P, Savino M .
AFM imaging and theoretical modeling studies of sequence-dependent nucleosome positioning.
Biophysical chemistry (Print);124: 81-89

Denti M.A., Rosa A., D'Antona G., Sthandier O., De Angelis F.G., Nicoletti C., Allocca M., Pansarasa O., Parente V., Musarò A., Auricchio A., Bottinelli R. and Bozzoni I .
A chimeric AAV/antisense-U1 snRNA effectively rescues dystrophin syntesis and muscle function by local treatment of mdx mice.
Gene therapy (Basingstoke);17: 565-574

Pomponi M.; Censi V.; Di Girolamo V.; De Paolis A.; di Toppi LS.; Aromolo R.; Costantino P.; Cardarelli M .
Overexpression of Arabidopsis phytochelatin synthase in tobacco plants enhances Cd(2+) tolerance and accumulation but not translocation to the shoot. Planta.
Planta;20: 1-11

Cecchetti V., Altamura M.M., Serino G., Pomponi M., Falasca G., Costantino P . and Cardarelli M .
ROX1 , a gene induced by rolB is involved in procambial cell proliferation and xylem differentiation in tobacco stamen.
Plant journal (Print);49: 27-37

Smith AT, Livingston MR, Mai A , Filetici P , Queener SF, Sullivan WJ Jr.
Quinoline derivative MC1626, a putative GCN5 histone acetyltransferase (HAT) inhibitor, exhibits HAT-independent activity against Toxoplasma gondii.
Antimicrobial agents and chemotherapy (Print);51: 1109-1111

Mai A , Rotili D, Tarantino D, Ornaghi P, Tosi F, Vicidomini C, Sbardella G, Nebbioso A, Miceli M, Altucci L, Filetici P ,.  
Small-molecule inhibitors of histone acetyltransferase activity: identification and biological properties.
Journal of medicinal chemistry;16: 6897-6907

Grimaldi B, Coiro P, Filetici P , Berge E, Dobosy JR, Freitag M, Selker EU, Ballario P .
The Neurospora crassa White Collar-1 dependent blue light response requires acetylation of histone H3 lysine 14 by NGF-1.
Molecular biology of the cell;17: 4576-4583

Ishida C, Aranda C, Valenzuela L, Riego L, Deluna A, Recillas-Targa F, Filetici P , Lopez-Revilla R, Gonzalez A.
The UGA3-GLT1 intergenic region constitutes a promoter whose bidirectional nature is determined by chromatin organization in Saccharomyces cerevisiae.
Molecular microbiology (Print);59: 1790-1806

Pizzitutti F, Giansanti A, Ballario P , Ornaghi P, Torreri P, Ciccotti G, Filetici P .
The role of loop ZA and Pro371 in the function of yeast Gcn5p bromodomain revealed through molecular dynamics and experiment.
JMR. Journal of molecular recognition;19: 1-9

Mattiuzzo M , Fiore M , Ricordy R , Degrassi F .
Aneuploidy-inducing capacity of two widely used pesticides.
Carcinogenesis (N.Y., Print);27: 2511-2518

Rens W1, Torosantucci L2 , Degrassi F2 , Ferguson-Smith MA1.
Incomplete sister chromatid separation of long chromosome arms.
Chromosoma (Berl., Print);115: 481-490

Cherubini G, Petouchoff T, Grossi M, Piersanti S, Cundari E , Saggio I .
E1B55K-deleted adenovirus (ONYX-015) overrides G1/S and G2/M checkpoints and causes mitotic catastrophe and endoreduplication in p53-proficient normal cells.
Cell cycle (Georget. Tex.);5: 2244-2252

Piersanti S, Sacchetti B, Funari A, Di Cesare S, Bonci D, Cherubini G, Peschle C, Riminucci M, Bianco P, Saggio I .
Lentiviral transduction of human postnatal skeletal (stromal, mesenchymal) stem cells: in vivo transplantation and gene silencing.
Calcified tissue international;78: 372-384

Oricchio E, Saladino C, Iacovelli S, Soddu S, Cundari E .
ATM is Activated by Default in Mitosis, Localizes at Centrosomes and Monitors Mitotic Spindle Integrity.
Cell cycle (Georget. Tex.);5: 88-92

Foglietti C, Filocamo G, Cundari E , De Rinaldis E, Lahm A, Cortese R, Steinkuhler C.
Dissecting the biological functions of Drosophila histone deacetylases by RNA interference and transcriptional profiling.
The Journal of biological chemistry (Print);281: 17968-17976

Oricchio E, Saladino C, Iacovelli S, Soddu S, Cundari E .
Again on the difficulty of seeking ATM localization.
Cell cycle (Georget. Tex.);5: 1010

Giansanti MG , Bonaccorsi S , Kurek R, Farkas RM, Dimitri P, Fuller MT, Gatti M .
The class I PITP Giotto is required for Drosophila cytokinesis.
Current biology;16: 195-201

Ciapponi L, Cenci G, Gatti M .
The Drosophila Nbs protein functions in multiple pathways for the maintenance of genome stability.
Genetics (Austin Tex.);173: 1447-1454

Shaffer CD, Cenci G, Thompson B, Stephens GE, Slawson E, Adu-Wusu K, Gatti M ,.  
Elgin Elgin SC. The Large Isoform of Drosophila melanogaster Heterochromatin Protein 2 Plays a Critical Role in Gene Silencing and Chromosome Structure.
Genetics (Austin Tex.);174: 1189-1204

Bruno T.; De Nicola F.; Iezzi S. Lecis D.; D'Angelo C.; Di Padova M.; Corbi N.; Zannini L.; Jekimovs C.; Scarsella M.; Porrello A.;  Crescenzi M.; Leonetti C.; Khanna K.K.; Soddu S.; Floridi A.; Passananti C .; Delia D.;  Fanciulli, M.
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint.
Cancer cell (Print);473: 486

Andrea Frustaci; Cristina Chimenti; Maurizio Pieroni; Luisa Salvatori; Emanuela Morgante; Patrizio Sale; Elisabetta Ferretti; Elisa Petrangeli; Alberto Gulino; Matteo Antonio Russo.
Cell death, proliferation and repair in human myocarditis responding to immunosuppressive therapy.
Modern pathology;19: 755-765

Stefania Mariani; Luisa Salvatori; Sabrina Basciani; Mario Arizzi; Giorgio Franco; Elisa Petrangeli; Giovanni Spera; Lucio Gnessi.
Expression and cellular localization of follicle-stimulating hormone receptor in normal human prostate, benign prostatic hyperplasia and prostate cancer.
The Journal of urology;175: 2072-2077

Xin Deng 1,3; Jonathan Phillips 1,2; Anne Brautigam 1; Peter Engstrom 4; Henrik Johannesson 4; Pieter B.F. Ouwerkerk 5; Ida Ruberti 6; Julio Salinas 7; Pablo Vera 8; Rina Iannacone 9; Annemarie H. Meijer 5; Dorothea Bartels 1,2.  
A homeodomain leucine zipper gene from Craterostigma plantagineum regulates abscisic acid responsive gene expression and physiological responses.
Plant molecular biology;61: 469-489

Presutti C., Rosati J ., Vincenti S. and Nasi S .
Non coding RNA and brain.
BMC neuroscience (Online);7: 1s5

Vogel C; Morea V.  
Duplication, divergence and formation of novel protein topologies.
BioEssays;28: 973-978

Corbo RM; Gambina G; Ruggeri M; Scacchi R.  
Association of estrogen receptor alpha (ESR1) PvuII and XbaI polymorphisms with sporadic Alzheimer's disease and their effect on apolipoprotein E concentrations.
Dementia and geriatric cognitive disorders;22: 67-72

Corbo RM; Prevost M; Raussens V; Gambina G; Moretto G; Scacchi R.  
Structural and phylogenetic approaches to assess the significance of human Apolipoprotein E variation.
Molecular genetics and metabolism (Print);89: 261-269

Lucarelli P ., Rizzo R., Gagliano A., Palmarino M., Volzone A., Arpino C., Curatolo P.
Association between D18S474 locus on chromosome 18q12 and idiopathic generalized epilepsy.
Brain & development (Tokyo, 1979)

Spinella F, Rosano L, Di Castro V, Decandia S, Albini A. Nicotra MR, Natali PG, Bagnato A.
Green tea polyphenol epigallocatechin-3-gallate inhibits the endothelin axis and downstream signaling pathways in ovarian carcinoma.
Molecular cancer therapeutics;5: 1483-1492

Uccini S, Colarossi C, Scarpino S, Boldrini R, Natali PG, Nicotra MR, Perla FM, Mannarino O, Altavista P, Boglino C, Cappelli CA, Cozzi D, Donfrancesco A, Kokai G, Losty PD, McDowell HP, Dominici C.
Morphological and molecular assessment of apoptotic mechanisms in peripheral neuroblastic tumours.
British Journal of Cancer;1: 49-55

Rosano L, Spinella F, Di Castro V, Dedhar S, Nicotra MR, Natali PG, Bagnato A.
Integrin-linked kinase functions as a downstream mediator of endothelin-1 to promote invasive behavior in ovarian carcinoma.
Molecular cancer therapeutics;4: 833-842

Mischiati C, Natali PG, Sereni A, Sibilio L, Giorda E, Cappellacci S, Nicotra MR, Mariani G, Di Filippo F, Catricala C, Gambari R, Grammatico P, Giacomini P.
cDNA-array profiling of melanomas and paired melanocyte cultures.
Journal of cellular physiology (Print);3: 697-705

Coral S, Sigalotti L, Colizzi F, Spessotto A, Nardi G, Cortini E, Pezzani L, Fratta E, Fonsatti E, Di Giacomo AM, Nicotra MR, Natali PG, Altomonte M, Maio M.
Phenotypic and functional changes of human melanoma xenografts induced by DNA hypomethylation: immunotherapeutic implications.
Journal of cellular physiology (Print);1: 58-96

Chichiarelli S., Ferraro A., Altieri F., Eufemi M., Coppari S., Grillo C., Arcangeli V., Turano C.
The stress protein ERp57/GRP58 binds specific DNA sequences in HeLa cells.
Journal of cellular physiology (Print);210: 343-351

Fontana M., Pecci L . , Schinina’ M.E., Montefoschi G., and Rosei M.A.
Oxidative and nitrative modification of enkephalins by reactive nitrogen species.
Free radical research;40: 697-706

Fontana M., Dupre’ S., and Pecci L .
The reactivity of hypotaurine and 20 cysteinesulfinic acid with peroxynitrite.
Advances in experimental medicine and biology;583: 15-24

Chiani F , Di Felice F, Camilloni G .
SIR2 modifies histone H4-K16 acetylation and affects superhelicity in the ARS region of plasmid chromatin in Saccharomyces cerevisiae .
Nucleic acids research;34: 5426-5437

Cruciani F, La Fratta R , Torroni A, Underhill PA, Scozzari R.
Molecular dissection of the Y chromosome haplogroup E-M78 (E3b1a): a posteriori evaulation of a microsatellite-network-based approach through six new biallelic markers.
Human mutation;27: 831-832

De Luca M, Lavia P , Guarguaglini G .
A functional interplay between Aurora-A, Plk1 and TPX2 at spindle poles: Plk1 controls centrosomal localization of Aurora-A and TPX2 spindle association.
Cell cycle (Georget. Tex.);5: 296-303

Paolozzi L.; Ghelardini P.
The bacteriophage MU.

Grillo C; D'Ambrosio C; Scaloni A; Maceroni M; Merluzzi S; Turano C; Altieri F.
Cooperative activity of ref-1/ape and erp57 in reductive activation of transcription factors.
Free radical biology & medicine;41: 1113-1123

Simona Panelli; Giuseppe Damiani; Luca Espen; Gioacchino Micheli; Vittorio Sgaramella.  
Towards the analysis of the genomes of single cells: further characterisation of the multiple displacement amplification.
Gene (Amst.);372: 1-7

Tessitore A., Parisi F., Denti M.A., Allocca M., Di Vicino U., Domenici L., Bozzoni I ., Auricchio A.
Preferential silencing of a common dominant rhodopsin mutation does not inhibit retinal degeneration in a transgenic model.
Molecular therapy (Print);14: 565-574

Franceschin M, Rossetti L, D'Ambrosio A, Schirripa S, Bianco A, Ortaggi G, Savino M , Schultes C, Neidle S. Franceschin, M.; Rossetti, L.; D’ambrosio, A.; Schirripa, S.; Bianco, A.; Ortaggi, G.; Savino, M.; Schristoph, C.; Neidle S.
Natural and synthetic G-quadruplex interactive berberine derivatives.
Bioorganic & medicinal chemistry letters (Print);16: 1707-1711

I Ruberti (1); G Sessa (1); G Morelli (2).  
Functional analysis of transcription factors by microparticle bombardment.

Perluigi, M (Perluigi, Marzia) 4 ; Joshi, G (Joshi, Gururaj)1-2 ; Sultana, R (Sultana, Rukhsana)1-2; Calabrese, V (Calabrese, Vittorio)3; De Marco, C (De Marco, Carlo)4 ; Coccia, R (Coccia, Raffaella)4; Cini, C (Cini, Chiara)4 ; Butterfield, DA (Butterfield, D. Allan) 1-2.  
In vivo protective effects of ferulic acid ethyl ester against amyloid-beta peptide 1-42-induced oxidative stress.
Journal of neuroscience research;84: 418-426

Mancuso, C (Mancuso, Cesare); Perluigi, M (Perluigi, Marzia); Cini, C (Cini, Chiara); De Marco, C (De Marco, Carlo); Stella, AMG (Stella, Anna Maria Giuffrida); Calabrese, V (Calabrese, Vittorio).  
Heme oxygenase and cyclooxygenase in the central nervous system: A functional interplay.
Journal of neuroscience research;84: 1385-1391

Butterfield, DA (Butterfield, DA); Reed, T (Reed, T); Perluigi, M (Perluigi, M); De Marco, C (De Marco, C); Coccia, R (Coccia, R); Cini, C (Cini, C); Sultana, R (Sultana, R).  
Elevated protein-bound levels of the lipid peroxidation product, 4-hydroxy-2-nonenal, in brain from persons with mild cognitive impairment.
Neuroscience letters (Print);397: 170-173