I am an expert in core Bioinformatics and Structural Bioinformatics techniques including: Druggability Predictions, Drug Design, Homology Modelling, Fold Recognition, Molecular Dynamics, Montecarlo Simulations, Antibodies, Proteins and Peptides Design, Next Generation Sequencing (Genome, Exome, Rna-Seq), Microarray, Methylation, Proteomics, Network and Pathway Analysis and machine learning algorithms.

1: di Micco P, Antolin AA, Mitsopoulos C, Villasclaras-Fernandez E, Sanfelice D, Dolciami D, Ramagiri P, Mica IL, Tym JE, Gingrich PW, Hu H, Workman P, Al-Lazikani B. canSAR: update to the cancer translational research and drug discovery knowledgebase. Nucleic Acids Res. 2023 Jan 6;51(D1):D1212-D1219. doi:10.1093/nar/gkac1004. PMID: 36624665; PMCID: PMC9825411.

2: Bruscalupi G, Di Micco P, Failla CM, Pascarella G, Morea V, Saliola M, De Paolis A, Venditti S, Mauro ML. Arabidopsis thaliana sirtuins control proliferation and glutamate dehydrogenase activity. Plant Physiol Biochem. 2023 Jan;194:236-245. doi: 10.1016/j.plaphy.2022.11.007. Epub 2022 Nov 11. PMID: 36436414.

3: Colotti G, Failla CM, Lacal PM, Ungarelli M, Ruffini F, Di Micco P, Orecchia A, Morea V. Neuropilin-1 is required for endothelial cell adhesion to soluble vascular endothelial growth factor receptor 1. FEBS J. 2022 Jan;289(1):183-198. doi: 10.1111/febs.16119. Epub 2021 Aug 27. PMID: 34252269; PMCID: PMC9290910.

4: Spitaleri A, Zia SR, Di Micco P, Al-Lazikani B, Soler MA, Rocchia W. Tuning Local Hydration Enables a Deeper Understanding of Protein-Ligand Binding: The PP1-Src Kinase Case. J Phys Chem Lett. 2021 Jan 14;12(1):49-58. doi:10.1021/acs.jpclett.0c03075. Epub 2020 Dec 10. PMID: 33300337; PMCID:PMC7812613.

5: Mitsopoulos C, Di Micco P, Fernandez EV, Dolciami D, Holt E, Mica IL, Coker EA, Tym JE, Campbell J, Che KH, Ozer B, Kannas C, Antolin AA, Workman P, Al-Lazikani B. canSAR: update to the cancer translational research and drug discovery knowledgebase. Nucleic Acids Res. 2021 Jan 8;49(D1):D1074-D1082. doi:10.1093/nar/gkaa1059. PMID: 33219674; PMCID: PMC7778970.

6: Falvo E, Malagrinò F, Arcovito A, Fazi F, Colotti G, Tremante E, Di Micco P, Braca A, Opri R, Giuffrè A, Fracasso G, Ceci P. The presence of glutamate residues on the PAS sequence of the stimuli-sensitive nano-ferritin improves in vivo biodistribution and mitoxantrone encapsulation homogeneity. J Control Release. 2018 Apr 10;275:177-185. doi: 10.1016/j.jconrel.2018.02.025. Epub 2018 Feb 20. PMID: 29474961.

7: Donini M, Lombardi R, Lonoce C, Di Carli M, Marusic C, Morea V, Di Micco P. Antibody proteolysis: a common picture emerging from plants. Bioengineered. 2015;6(5):299-302. doi: 10.1080/21655979.2015.1067740. Epub 2015 Jul 17.

8: Di Micco P, Fazzi D'Orsi M, Morea V, Frontali L, Francisci S, Montanari A. The yeast model suggests the use of short peptides derived from mt LeuRS for the therapy of diseases due to mutations in several mt tRNAs. Biochim Biophys Acta. 2014 Dec;1843(12):3065-74. doi: 10.1016/j.bbamcr.2014.09.011. Epub 2014 Sep 28.

9: Perli E, Giordano C, Pisano A, Montanari A, Campese AF, Reyes A, Ghezzi D, Nasca A, Tuppen HA, Orlandi M, Di Micco P, Poser E, Taylor RW, Colotti G, Francisci S, Morea V, Frontali L, Zeviani M, d'Amati G. The isolated carboxy-terminal domain of human mitochondrial leucyl-tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells. EMBO Mol Med. 2014 Feb;6(2):169-82. doi:10.1002/emmm.201303198. Epub 2014 Jan 10. PMID:24413190; PMCID: PMC3927953.

10: Saccoccia F, Di Micco P, Boumis G, Brunori M, Koutris I, Miele AE, Morea V, Sriratana P, Williams DL, Bellelli A, Angelucci F. Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin. Structure. 2012 Mar 7;20(3):429-39. doi: 10.1016/j.str.2012.01.004. PMID: 22405002; PMCID: PMC3299984.