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Research groups at  IBPM pursue cross-disciplinary research by integrating different basic disciplines, ranging from chemistry to structural biology, biochemistry, bioinformatics, formal and molecular genetics, molecular biology, immunology and molecular oncology. 

A variety of forefront methodologies and experimental systems have been developed  to approach complex biological processes, with a particular focus on: studies of protein structure, evolution and function; the biological role of non coding RNAs; epigenetic mechanisms and epigenomics; molecular control of the cell cycle and cell division; control of cell proliferation and cell death; plant cell biology and differentiation;  and the development of model systems in studies of human pathology and neurodegenerative diseases.