• Istituto di Biologia e Patologia Molecolari

Pubblicazioni 2017

Vicente, João B.; Colaço, Henrique G.; Malagrinò, Francesca; Malagrinò, Francesca; Santo, Paulo E.; Santo, Paulo E.; Gutierres, André; Bandeiras, Tiago M.; Bandeiras, Tiago M.; Leandro, Paula; Brito, José A.; Giuffrè, Alessandro.  
A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine beta -Synthase: Increased CO Reactivity as a Novel Molecular Mechanism of Pathogenicity?. 
Oxidative medicine and cellular longevity (Online)8940321
 
Durano D.; Lukacs A.; Di Felice F.; Micheli G.; Camilloni G. 
A novel role for Nhp6 proteins in histone gene regulation in Saccharomyces cerevisiae. 
International journal of biochemistry & cell biology: 76-83
 
Merigliano, Chiara; Marzio, Antonio; Renda, Fioranna; Somma, Maria Patrizia; Gatti, Maurizio; Verni, Fiammetta.  
A Role for the Twins Protein Phosphatase (PP2A-B55) in the Maintenance of Drosophila Genome Integrity. 
Genetics (Austin Tex.): 1151-1178
 
Cecchetti V.; Celebrin D.; Napoli N.; Ghelli R.; Brunetti P.; Costantino P.; Cardarelli M. 
An auxin maximum in the middle layer controls stamen development and pollen maturation in Arabidopsis. 
New phytologist (Print): 1194-1207
 
Cini, Alberto; Ceci, Pierpaolo; Falvo, Elisabetta; Gatteschi, Dante; Fittipaldi, Maria.  
An EPR Study of Small Magnetic Nanoparticles. 
Zeitschrift für physikalische Chemie (Münch., 1991): 745-757
 
Genovese, Ilaria; Fiorillo, Annarita; Ilari, Andrea; Masciarelli, Silvia; Fazi, Francesco; Colotti, Gianni.  
Binding of doxorubicin to Sorcin impairs cell death and increases drug resistance in cancer cells. 
Cell death and disease
 
Frappaolo, Anna; Sechi, Stefano; Kumagai, Tadahiro; Robinson, Sarah; Fraschini, Roberta; Ghahnavieh, Angela Karimpour; Belloni, Giorgio; Piergentili, Roberto; Tiemeyer, Katherine H; Tiemeyer, Michael; Giansanti, Maria Grazia.  
COG7 deficiency in generates multifaceted developmental, behavioral, and protein glycosylation phenotypes. 
Journal of cell science (Online)
 
Forte, Elena; Borisov, Vitaliy B.; Vicente, João B.; Giuffrè, Alessandro.  
Cytochrome bd and Gaseous Ligands in Bacterial Physiology. 
Advances in Microbial Physiology: 171-234
 
Sinibaldi, Alberto; Sampaoli, Camilla; Danz, Norbert; Munzert, Peter; Sibilio, Leonardo; Sonntag, Frank; Occhicone, Agostino; Falvo, Elisabetta; Tremante, Elisa; Giacomini, Patrizio; Michelotti, Francesco.  
Detection of soluble ERBB2 in breast cancer cell lysates using a combined label-free/fluorescence platform based on Bloch surface waves. 
Biosensors & bioelectronics: 125-130
 
Laneve, Pietro; Piacentini, Lucia; Casale, Assunta Maria; Capauto, Davide; Gioia, Ubaldo; Cappucci, Ugo; Di Carlo, Valerio; Bozzoni, Irene; Di Micco, Patrizio; Morea, Veronica; Di Franco, Carmela Antonia; Caffarelli, Elisa.  
Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration. 
Scientific reports (Nature Publishing Group)
 
Errichelli, Lorenzo; Modigliani, Stefano Dini; Laneve, Pietro; Colantoni, Alessio; Legnini, Ivano; Capauto, Davide; Rosa, Alessandro; De Santis, Riccardo; Scarfo, Rebecca; Peruzzi, Giovanna; Lu, Lei; Caffarelli, Elisa; Shneider, Neil A.; Morlando, Mariangela; Bozzoni, Irene.  
FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons. 
Nature communications
 
Barroeta Seijas, Amairelys Belen; Simonetti, Sonia; Vitale, Sara; Runci, Daniele; Quinci, Angela Caterina; Soriani, Alessandra; Criscuoli, Mattia; Filippi, Irene; Naldini, Antonella; Sacchetti, Federico Maria; Tarantino, Umberto; Oliva, Francesco; Piccirilli, Eleonora; Santoni, Angela; Di Rosa, Francesca.  
GM-CSF Inhibits c-Kit and SCF Expression by Bone Marrow-Derived Dendritic Cells. 
Frontiers in immunology147
 
De Mori R.; Romani M.; D'Arrigo S.; Zaki M.S.; Lorefice E.; Tardivo S.; Biagini T.; Stanley V.; Musaev D.; Fluss J.; Micalizzi A.; Nuovo S.; Illi B.; Chiapparini L.; Di Marcotullio L.; Issa M.Y.; Anello D.; Casella A.; Ginevrino M.; Leggins A.S.; Roosing S.; Alfonsi R.; Rosati J.; Schot R.; Mancini G.M.S.; Bertini E.; Dobyns W.B.; Mazza T.; Gleeson J.G.; Valente E.M. 
Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects. 
American journal of human genetics: 552-563
 
Asteriti, Italia Anna; Daidone, Frederick; Colotti, Gianni; Rinaldo, Serena; Lavia, Patrizia; Guarguaglini, Giulia; Paiardini, Alessandro.  
Identification of small molecule inhibitors of the Aurora-A/TPX2 complex. 
Oncotarget: 32117-32133
 
Gilistro E.; de Turris V.; Damizia M.; Verrico A.; Moroni S.; De Santis R.; Rosa A.; Lavia P. 
Importin-beta and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function. 
Journal of cell science: 2564-2578
 
Di Cesare E.; Verrico A.; Miele A.; Giubettini M.; Rovella P.; Coluccia A.; Famiglini V.; La Regina G.; Cundari E.; Silvestri R.; Lavia P. 
Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules. 
Oncotarget: 19738-19759
 
Di Domenico F.; Tramutola A.; Foppoli C.; Head E.; Perluigi M.; Butterfield D.A. 
MTOR in Down syndrome: Role in Aß and tau neuropathology and transition to Alzheimer disease-like dementia. 
Free radical biology & medicine
 
Parente, Margarida R.; Forte, Elena; Falabella, Micol; Boneca, Ivo G.; Boneca, Ivo G.; Teixeira, Miguel; Giuffrè, Alessandro; Saraiva, Lígia M. 
Nitrosative stress defences of the enterohepatic pathogenic bacterium Helicobacter pullorum. 
Scientific reports (Nature Publishing Group): 1-13
 
Gabellini, Chiara; Trisciuoglio, Daniela; Bufalo, Donatella Del.  
Non-canonical roles of Bcl-2 and Bcl-xL proteins: Relevance of BH4 domain. 
Carcinogenesis (N.Y., Print): 579-587
 
Genovese I.; Ilari A.; Assaraf Y.G.; Fazi F.; Colotti G. 
Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins. 
Drug resistance updates (Print): 23-46
 
Soriani, Alessandra; Borrelli, Cristiana; Ricci, Biancamaria; Molfetta, Rosa; Zingoni, Alessandra; Fionda, Cinzia; Carnevale, Silvia; Abruzzese, Maria Pia; Petrucci, Maria Teresa; Ricciardi, Maria Rosaria; La Regina, Giuseppe; Di Cesare, Erica; Lavia, Patrizia; Silvestri, Romano; Paolini, Rossella; Cippitelli, Marco; Santoni, Angela.  
p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells. 
ONCOIMMUNOLOGY
 
Colicchia V.; Petroni M.; Guarguaglini G.; Sardina F.; Sahun-Roncero M.; Carbonari M.; Ricci B.; Heil C.; Capalbo C.; Belardinilli F.; Coppa A.; Peruzzi G.; Screpanti I.; Lavia P.; Gulino A.; Giannini G. 
PARP inhibitors enhance replication stress and cause mitotic catastrophe in MYCN-dependent neuroblastoma. 
Oncogene (Basingstoke)
 
Gerace R.; Montanini B.; Proietto M.; Levati E.; De Luca C.; Brenna A.; Filetici P.; Kohler A.; Ottonello S.; Ballario P. 
Photoreceptors in the dark: A functional white collar-like complex and other putative light-sensing components encoded by the genome of the subterranean fungus Tuber melanosporum. 
Fungal biology (Print): 253-263
 
Calisti, Lorenzo; Benni, Irene; Trabuco, Matilde Cardoso; Baiocco, Paola; Ruzicka, Barbara; Boffi, Alberto; Falvo, Elisabetta; Malatesta, Francesco; Bonamore, Alessandra.  
Probing bulky ligand entry in engineered archaeal ferritins. 
Biochimica et biophysica acta. G, General subjects (Print): 450-456
 
Camerini, Serena; Bocedi, Alessio; Cecchetti, Serena; Casella, Marialuisa; Carbo, Miriam; Morea, Veronica; Pozio, Edoardo; Ricci, Giorgio; Lalle, Marco.  
Proteomic and functional analyses reveal pleiotropic action of the anti-tumoral compound NBDHEX in Giardia duodenalis. 
International journal for parasitology, drugs and drug resistance: 147-158
 
di Salvo, Martino L; Mastrangelo, Mario; Nogues, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo.  
Pyridoxine-5'-phosphate oxidase (Pnpo) deficiency: Clinical and biochemical alterations associated with the C.347g>A (P.·Arg116gln) mutation. 
Molecular genetics and metabolism (Print): 135-142
 
Sechi S.; Frappaolo A.; Fraschini R.; Capalbo L.; Gottardo M.; Belloni G.; Glover D.M.; Wainman A.; Giansanti M.G. 
Rab1 interacts with GOLPH3 and controls Golgi structure and contractile ring constriction during cytokinesis in Drosophila melanogaster. 
Open biology
 
Caterina Gulìa, Stefano Baldassarra, Fabrizio Signore, Giuliano Rigon, Valerio Pizzuti, Marco Gaffi, Vito Briganti, Alessandro Porrello, Roberto Piergentili.  
Role of Non-Coding RNAs in the Etiology of Bladder Cancer. 
Genes (Basel)
 
Leuzzi, Adriano; Grossi, Milena; Di Martino, Maria Letizia; Pasqua, Martina; Micheli, Gioacchino; Colonna, Bianca; Prosseda, Gianni.  
Role of the SRRz/Rz lambdoid lysis cassette in the pathoadaptive evolution of Shigella. 
International journal of medical microbiology (Print)
 
Tramonti, Angela; Milano, Teresa; Nardella, Caterina; di Salvo, Martino L.; Pascarella, Stefano; Contestabile, Roberto.  
Salmonella typhimurium PtsJ is a novel MocR-like transcriptional repressor involved in regulating the vitamin B-6 salvage pathway. 
The FEBS journal (Print): 466-484
 
Mariani S.; Di Rocco G.; Toietta G.; Russo M.A.; Petrangeli E.; Salvatori L. 
Sirtuins 1-7 expression in human adipose-derived stem cells from subcutaneous and visceral fat depots: influence of obesity and hypoxia. 
Endocrine (Basingstoke): 1-9
 
Ferrara, M; Sessa, G; Fiore, M; Bernard, F; Asteriti, I A; Cundari, E; Colotti, G; Ferla, S; Desideri, M; Buglioni, S; Trisciuoglio, D; Del Bufalo, D; Brancale, A; Degrassi, F.  
Small molecules targeted to the microtubule-Hec1 interaction inhibit cancer cell growth through microtubule stabilization. 
Oncogene (Basingstoke, Online)
 
Scaglione, Antonella; Scaglione, Antonella; Fullone, Maria Rosaria; Montemiglio, Linda Celeste; Montemiglio, Linda Celeste; Parisi, Giacomo; Parisi, Giacomo; Zamparelli, Carlotta; Vallone, Beatrice; Vallone, Beatrice; Savino, Carmelinda; Grgurina, Ingeborg.  
Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity. 
The FEBS journal (Print): 2981-2999
 
Amidani, Davide; Tramonti, Angela; Canosa, Andrea Valeria; Campanini, Barbara; Maggi, Stefano; Milano, Teresa; di Salvo, Martino L.; Pascarella, Stefano; Contestabile, Roberto; Bettati, Stefano; Rivetti, Claudio.  
Study of DNA binding and bending by Bacillus subtilis GabR, a PLP-dependent transcription factor. 
Biochimica et biophysica acta. G, General subjects (Print): 3474-3489
 
Scaglione A.; Montemiglio L.C.; Parisi G.; Asteriti I.A.; Bruni R.; Cerutti G.; Testi C.; Savino C.; Mancia F.; Lavia P.; Vallone B. 
Subcellular localization of the five members of the human steroid 5?-reductase family. 
Biochimie (Online): 99-106
 
Antonioletti R.; Righi G.; Ricelli A.; Rossetti I.; Viglianti A.; Frezza C.; Marino-Merlo F.; Macchi B. 
Synthesis and biological evaluation of styrylheterocycles analogs of resveratrol as apoptosis-inducing agents. 
Current organic chemistry: 939-948
 
G. Righi, R. Pelagalli, V. Isoni, I. Trotta, R. Dallocchio, A. Dessì, B.Macchi, C. Frezza, I. Rossetti, P. Bovicelli.  
Synthesis, molecular modelling and biological evaluation of two new chicoric acid analogs. 
Natural product research (Online): 397-403
 
Laneve, Pietro; Po, Agnese; Favia, Annarita; Legnini, Ivano; Alfano, Vincenzo; Rea, Jessica; Di Carlo, Valerio; Bevilacqua, Valeria; Miele, Evelina; Mastronuzzi, Angela; Carai, Andrea; Locatelli, Franco; Bozzoni, Irene; Ferretti, Elisabetta; Caffarelli, Elisa.  
The long noncoding RNA linc-NeD125 controls the expression of medulloblastoma driver genes by microRNA sponge activity. 
Oncotarget
 
Traversi, Gianandrea; Fiore, Mario; Percario, Zulema; Degrassi, Francesca; Cozzi, Renata.  
The resveratrol analogue trimethoxystilbene inhibits cancer cell growth by inducing multipolar cell mitosis. 
Molecular carcinogenesis (Print): 1117-1126
 
Damiani, Verena; Falvo, Elisabetta; Fracasso, Giulio; Federici, Luca; Pitea, Martina; De laurenzi, Vincenzo; Sala, Gianluca; Ceci, Pierpaolo.  
Therapeutic Efficacy of the Novel Stimuli-Sensitive Nano-Ferritins Containing Doxorubicin in a Head and Neck Cancer Model. 
International journal of molecular sciences (Online)
 
Gonzalez, Laetitia; Cundari, Enrico; Leyns, Luc; Kirsch-Volders, Micheline.  
Towards a New Paradigm in Nano-Genotoxicology: Facing Complexity of Nanomaterials' Cellular Interactions and Effects. 
Basic & clinical pharmacology & toxicology (Print): 23-29
 
Mosca, Luciana; Falvo, Elisabetta; Ceci, Pierpaolo; Poser, Elena; Genovese, Ilaria; Guarguaglini, Giulia; Colotti, Gianni.  
Use of ferritin-based metal-encapsulated nanocarriers as anticancer agents. 
Research. 3, Applied sciences
 
N. CAPOZZA, C. GULIA, Z. HEIDARI BATENI, A. ZANGARI, S. GIGLI, V. BRIGANTI, S. TURSINI, C.J. KOH, M. GAFFI, S. BALDASSARRA, F. SIGNORE, A. PORRELLO, R. PIERGENTILI.  
Vesicoureteral reflux in infants: what do we know about the gender prevalence by age?. 
European review for medical and pharmacological sciences: 5321-5329
 
Frappaolo A.; Sechi S.; Belloni G.; Piergentili R.; Giansanti M.G. 
Visualization of cleavage furrow proteins in fixed dividing spermatocytes. 
Methods in cell biology: 85-103
 
Bolondi A.; Caldarelli F.; Di Felice F.; Durano D.; Germani G.; Michetti L.; Tramutolo A.; Micheli G.; Camilloni G. 
What is a Gene? A Two Sided View. 
Evolutionary biology: 1-4
 
Ilari A.; Fiorillo A.; Genovese I.; Colotti G. 
An update on structural insights into the enzymes of the polyamine-trypanothione pathway: Targets for new drugs against leishmaniasis. 
Future medicinal chemistry (Print): 61-77
 
Trisciuoglio, Daniela; Tupone, Maria Grazia; Desideri, Marianna; Di Martile, Marta; Gabellini, Chiara; Buglioni, Simonetta; Pallocca, Matteo; Alessandrini, Gabriele; D'Aguanno, Simona; Del Bufalo, Donatella.  
BCL-X overexpression promotes tumor progression-associated properties. 
Cell death and disease3216
 
di Salvo, Martino L.; Mastrangelo, Mario; Nogués, Isabel; Tolve, Manuela; Paiardini, Alessandro; Carducci, Carla; Mei, Davide; Montomoli, Martino; Tramonti, Angela; Guerrini, Renzo; Contestabile, Roberto; Leuzzi, Vincenzo.  
Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5?-phosphate oxidase (PNPO). 
data in brief Elsevier: 868-875
 
Morea V.; Bidollari E.; Colotti G.; Fiorillo A.; Rosati J.; de Filippis L.; Squitieri F.; Ilari A. 
Glucose transportation in the brain and its impairment in Huntington disease: one more shade of the energetic metabolism failure?. 
Amino acids (Wien, Print): 1-11
 
Saccoliti, F ; Angiulli, G ; Pupo, G; Pescatori, L ; Madia, VN ; Messore, A ; Colotti, G ; Fiorillo, A ; Scipione, L ; Gramiccia, M ; Di Muccio, T ; Di Santo, R ]; Costi, R ; Ilari, A.  
Inhibition of Leishmania infantum trypanothione reductase by diaryl sulfide derivatives. 
Journal of enzyme inhibition and medicinal chemistry (Print): 304-310