• Istituto di Biologia e Patologia Molecolari

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Data Controller and Owner

CNR - Piazzale Aldo Moro, 7 - 00185 Roma, Italy
segreteria.ibpm@cnr.it


 
 
 

 
 

 
 

 
 

 
MISSION    The IBPM develops research in the following areas

  • Structural bases of protein and nucleic acid function, particularly in regulation of the expression of genes and genomes, of structural and regulatory proteins, and of molecules involved in the immune response;
  • Molecular mechanisms of evolution and differentiation in animal and plants and biotechnological and biomedical applications;
  • Design, synthesis, biosynthesis, purification and characterization of biologically active molecules: development of innovative chemical and molecular methods; characterization of their mechanisms of action; implications in human health.
 
 
IBPM HIGHLIGHTS
 

 
RESEARCH AWARDS

Tom Wahlig Foundation for spastic hereditary paraplegy
Francesca Sardina

DSB-CNR awards to starting scientists
Eugenia D'Atanasio
Anna Frappaolo


Fondazione Veronesi research fellowship
Francesca Sardina

Rome city council award “RomaRose - Non solo 8 marzo”
Rossella Lucà

go to awards
 

 
RECENT PUBLICATIONS

Nose-to-brain selective drug delivery to glioma via ferritin-based nanovectors reduces tumor growth and improves survival rate.
Marrocco F, et al. Cell Death Dis. 2024 Apr 13
 
Cul-4 inhibition rescues spastin levels and reduces defects in hereditary spastic paraplegia models.
Sardina F, et al. Brain. 2024 Mar 29
 
Fragment Merging, Growing, and Linking Identify New Trypanothione Reductase Inhibitors for Leishmaniasis.
Exertier C, et al.. J Med Chem. 2024 Jan 11
 
The genomic echoes of the last Green Sahara on the Fulani and Sahelian people
E. D'Atanasio et al. Curr Biology 2023
 
HAX1 is a novel binding partner of Che-1/AATF. Implications in oxidative stress cell response
Pisani C et al. Biochim Biophys Acta Mol Cell Res. 2024 Jan
 
The long noncoding RNA nHOTAIRM1 is necessary for differentiation and activity of iPSC-derived spinal motor neurons
Tollis P et al. Cell Death Dis. 2023
 
PARP1 allows proper telomere replication through TRF1 poly (ADP-ribosyl)ation and helicase recruitment.
Maresca C et al. Commun Biol 2023
 
AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
Asteriti IA et al. Life Sci Alliance 2023
 
The interaction of ß-arrestin1 with talin1 driven by endothelin A receptor as a feature of a5ß1 integrin activation in high-grade serous ovarian cancer.
Masi I et al. Cell Death Dis 2023
 
Blockage of autophagosome-lysosome fusion through SNAP29 O-GlcNAcylation promotes apoptosis via ROS production.
Pellegrini et al. Autophagy. 2023