My main research interest is the characterization of epigenetic mechanisms of gene expression regulation in the nervous system, with a principal focus on the role of non-coding RNAs in homeostatic neuronal behaviors and developmental diseases. My experimental approach ranges from a biochemical characterization of purified macromolecules to their functional analysis in cell systems and animal models.
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Selected publications (last 10 years)
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Carlo Presutti, Dipartimento di Biologia e Biotecnologie "C.Darwin", Sapienza Università di Roma |
Cecilia Mannironi, Ph.D.
Via degli Apuli, 4
Roma, 00185
Tel: +39-06-4457526/49917912
Indirizzo e-mail: cecilia.mannironi@uniroma1.it
Academic Qualifications
1987 Ph.D. in Pharmacological Research, Istituto di Ricerche Farmacologiche “Mario Negri”, Milano, Italy
1983 Biological Science Degree, Università degli Studi di Pisa, Pisa, Italy.
Positions 1981-1983 Undergraduate student, Istituto di Mutagenesi e Differenziamento, Laboratorio di Enzimologia, Supervisor: Prof. C.Bauer, CNR, Pisa. 1983-1984 Visiting research fellow, Istituto di Genetica, University of Pisa. 1984-1987 Ph.D. student, Mario Negri Institute for Pharmacological Research, Milan. Laboratory of In vitro Cancer Chemotherapy, Tutor: Maurizio D’Incalci. 1987-1988 Postdoctoral research fellow, Mario Negri Institute for Pharmacological Research. Milan, Laboratory of In vitro Cancer Chemotherapy. 1988-1991 Postdoctoral research fellow, National Cancer Institute, National Institute of Health, Bethesda, Laboratory of Dr. William Bonner. 1991-2013 Senior Researcher, Istituto di Biologia Cellulare, CNR, Roma. 2013- Researcher, Istituto di Biologia e Patologia Molecolari, CNR, Roma. 2006-2009 Teaching Assistant, Course “Molecular Neurobiology”, Master Degree in Neurobiology, Sapienza University of Rome, Italy. 2009-2017 Contract Professor, Course “Molecular Neurobiology”, Master Degree in Neurobiology, Sapienza University of Rome, Italy. 2017-2019 Contract Professor, Course “Molecular Neurobiology 1” (advanced course in Molecular Neurobiology), Master Degree in Neurobiology, Sapienza University of Rome, Italy. Supervisor of undergraduate /master/PhD students, University of Rome
Seminars and laboratory teaching for High School students
Scientific Appointments Member of the Eumodic European Consortium for mouse functional genomics and phenotyping (http://www.eumodic.org) built on the work in the EUMORPHIA project funded by the European Commission under the Framework 6 (Programme contract number LSHG-CT-2006-037188). Grants and Fellowships Partecipant to European Grants: LIFE2020-Regione Lazio - REG LAZIO; EUMODIC (The European MOuse DIsease Clinic), 2007; EURASNET (European alternative splicing network of excellence),
2006; EUCOMM (The European Mouse Genome Mutagenesis Program), 2006; MUGEN (Integrated functional genomics in mutant mouse models as tools to
investigate the complexity of human immunological disease), 2005. Fogarty Institution, Individual Postdoctoral Fellowship, 1989-1991 |